Skip to main content
Top
Published in: BMC Public Health 1/2013

Open Access 01-12-2013 | Study protocol

Anticipated regret to increase uptake of colorectal cancer screening in Scotland (ARTICS): study protocol for a randomised controlled trial

Authors: Ronan E O’Carroll, Robert JC Steele, Gillian Libby, Linda Brownlee, Julie A Chambers

Published in: BMC Public Health | Issue 1/2013

Login to get access

Abstract

Background

Colorectal cancer is the second leading cause of cancer deaths in the UK. Screening is key to early detection. The Scottish programme of colorectal cancer screening is running successfully, and involves all adults aged between 50 and 74 years being invited to post back a faecal sample for testing every 2 years. However, screening uptake is sub-optimal: for example rates for the period November 2009 to October 2011 ranged from just 39% for males living in the most deprived areas to 67% for least deprived females. Recent research has shown that asking people to consider the emotional consequences of not participating in screening (anticipated regret) can lead to a significant increase in screening uptake.

Methods/Design

We will test a simple anticipated regret manipulation, in a large randomised controlled trial with 60,000 members of the general public. They will be randomly allocated to one of 3 arms, no questionnaire, control questionnaire or anticipated regret questionnaire. The primary outcome will be screening test kit return. Results will also be examined by demographic variables (age, gender, deprivation) as these are currently related to screening kit return.

Discussion

If this anticipated regret intervention leads to a significant increase in colorectal cancer screening kit returns, this would represent a rare example of a theoretically-driven, simple intervention that could result in earlier detection of colorectal cancer and many more lives saved.

Trial registration

Current Controlled trials: ISRCTN74986452
Appendix
Available only for authorised users
Literature
1.
go back to reference Scottish Intercollegiate Guidelines Network (SIGN): Guideline No. 126: Diagnosis and management of Colorectal cancer. 2011, Edinburgh: SIGN Scottish Intercollegiate Guidelines Network (SIGN): Guideline No. 126: Diagnosis and management of Colorectal cancer. 2011, Edinburgh: SIGN
2.
go back to reference von Euler-Chelpin M, Brasso K, Lynge E: Determinants of participation in colorectal cancer screening with faecal occult blood testing. J Public Health (Oxf). 2010, 32: 395-405. 10.1093/pubmed/fdp115.CrossRef von Euler-Chelpin M, Brasso K, Lynge E: Determinants of participation in colorectal cancer screening with faecal occult blood testing. J Public Health (Oxf). 2010, 32: 395-405. 10.1093/pubmed/fdp115.CrossRef
3.
go back to reference Steele RJ, McClements PL, Libby G, Black R, Morton C, Birrell J, Mowat NA, Wilson JA, Kenicer M, Carey FA, Fraser CG: Results from the first three rounds of the Scottish demonstration pilot of FOBT screening for colorectal cancer. Gut. 2009, 58: 530-535. 10.1136/gut.2008.162883.CrossRefPubMed Steele RJ, McClements PL, Libby G, Black R, Morton C, Birrell J, Mowat NA, Wilson JA, Kenicer M, Carey FA, Fraser CG: Results from the first three rounds of the Scottish demonstration pilot of FOBT screening for colorectal cancer. Gut. 2009, 58: 530-535. 10.1136/gut.2008.162883.CrossRefPubMed
4.
go back to reference Towler B, Irwig L, Glasziou P, Kewenter J, Weller D, Silgay C: A systematic review of the effects of screening for colorectal cancer using the faecal occult blood test, hemoccult. BMJ. 1998, 317 (7158): 559-565. 10.1136/bmj.317.7158.559.CrossRefPubMedPubMedCentral Towler B, Irwig L, Glasziou P, Kewenter J, Weller D, Silgay C: A systematic review of the effects of screening for colorectal cancer using the faecal occult blood test, hemoccult. BMJ. 1998, 317 (7158): 559-565. 10.1136/bmj.317.7158.559.CrossRefPubMedPubMedCentral
5.
go back to reference Libby G, Brewster D, McClements PL, Carey FA, Black RJ, Birrell J, Fraser CG, Steele RJ: The impact of population-based faecal occult blood test screening on colorectal cancer mortality: a matched cohort study. Brit J Cancer. 2012, 107: 255-259. 10.1038/bjc.2012.277.CrossRefPubMedPubMedCentral Libby G, Brewster D, McClements PL, Carey FA, Black RJ, Birrell J, Fraser CG, Steele RJ: The impact of population-based faecal occult blood test screening on colorectal cancer mortality: a matched cohort study. Brit J Cancer. 2012, 107: 255-259. 10.1038/bjc.2012.277.CrossRefPubMedPubMedCentral
6.
go back to reference Strack F, Deutsch R: Reflective and impulsive determinants of social behavior. Pers Soc Psychol Rev. 2004, 8: 220-247. 10.1207/s15327957pspr0803_1.CrossRefPubMed Strack F, Deutsch R: Reflective and impulsive determinants of social behavior. Pers Soc Psychol Rev. 2004, 8: 220-247. 10.1207/s15327957pspr0803_1.CrossRefPubMed
7.
go back to reference Abraham C, Sheeran P: Acting on intentions: the role of anticipated regret. Brit J Soc Psychol. 2003, 42: 495-511. 10.1348/014466603322595248.CrossRef Abraham C, Sheeran P: Acting on intentions: the role of anticipated regret. Brit J Soc Psychol. 2003, 42: 495-511. 10.1348/014466603322595248.CrossRef
8.
go back to reference Sandberg T, Conner M: A mere measurement effect for anticipated regret: impacts on cervical screening attendance. Brit J Soc Psychol. 2009, 48: 221-236. 10.1348/014466608X347001.CrossRef Sandberg T, Conner M: A mere measurement effect for anticipated regret: impacts on cervical screening attendance. Brit J Soc Psychol. 2009, 48: 221-236. 10.1348/014466608X347001.CrossRef
9.
go back to reference Sandberg T, Conner M: Anticipated regret as an additional predictor in the theory of planned behaviour: a meta-analysis. Brit J Soc Psychol. 2008, 47: 589-606. 10.1348/014466607X258704.CrossRef Sandberg T, Conner M: Anticipated regret as an additional predictor in the theory of planned behaviour: a meta-analysis. Brit J Soc Psychol. 2008, 47: 589-606. 10.1348/014466607X258704.CrossRef
10.
go back to reference French DP, Sutton S: Reactivity of measurement in health psychology: How much of a problem is it? What can be done about it?. Brit J Health Psychol. 2010, 15: 453-468. 10.1348/135910710X492341.CrossRef French DP, Sutton S: Reactivity of measurement in health psychology: How much of a problem is it? What can be done about it?. Brit J Health Psychol. 2010, 15: 453-468. 10.1348/135910710X492341.CrossRef
11.
go back to reference Godin G, Sheeran P, Conner M, Germain M: Asking questions changes behavior: mere measurement effects on frequency of blood donation. Health Psychol. 2008, 27: 179-184.CrossRefPubMed Godin G, Sheeran P, Conner M, Germain M: Asking questions changes behavior: mere measurement effects on frequency of blood donation. Health Psychol. 2008, 27: 179-184.CrossRefPubMed
12.
go back to reference Godin G, Sheeran P, Conner M, Delage G, Germain M, Belanger-Gravel A, Naccache H: Which survey questions change behavior? Randomized controlled trial of mere measurement interventions. Health Psychol. 2010, 29: 636-644.CrossRefPubMed Godin G, Sheeran P, Conner M, Delage G, Germain M, Belanger-Gravel A, Naccache H: Which survey questions change behavior? Randomized controlled trial of mere measurement interventions. Health Psychol. 2010, 29: 636-644.CrossRefPubMed
13.
go back to reference Wallston KA, Wallston BS, DeVellis R: Development of the Multidimensional Health Locus of Control (MHLC) scales. Health Educ Monographs. 1978, 6: 160-170. 10.1177/109019817800600107.CrossRef Wallston KA, Wallston BS, DeVellis R: Development of the Multidimensional Health Locus of Control (MHLC) scales. Health Educ Monographs. 1978, 6: 160-170. 10.1177/109019817800600107.CrossRef
14.
go back to reference Miles A, Rainbow S, von Wagner C: Cancer fatalism and poor self-rated health mediate the association between socioeconomic status and uptake of colorectal cancer screening in England. Cancer Epidemiol Biomarkers Prev. 2011, 20: 2132-2140. 10.1158/1055-9965.EPI-11-0453.CrossRefPubMedPubMedCentral Miles A, Rainbow S, von Wagner C: Cancer fatalism and poor self-rated health mediate the association between socioeconomic status and uptake of colorectal cancer screening in England. Cancer Epidemiol Biomarkers Prev. 2011, 20: 2132-2140. 10.1158/1055-9965.EPI-11-0453.CrossRefPubMedPubMedCentral
15.
go back to reference Jones RM, Woolf SH, Cunningham TD, Johnson RE, Krist AH, Rothemich SF, Vernon SW: The relative importance of patient-reported barriers to colorectal cancer screening. Am J Prev Med. 2010, 38: 499-507. 10.1016/j.amepre.2010.01.020.CrossRefPubMedPubMedCentral Jones RM, Woolf SH, Cunningham TD, Johnson RE, Krist AH, Rothemich SF, Vernon SW: The relative importance of patient-reported barriers to colorectal cancer screening. Am J Prev Med. 2010, 38: 499-507. 10.1016/j.amepre.2010.01.020.CrossRefPubMedPubMedCentral
16.
go back to reference Chapple A, Ziebland S, Hewitson P, McPherson A: What affects the uptake of screening for bowel cancer using a faecal occult blood test (FOBT): a qualitative study. Soc Sci Med. 2008, 66: 2425-2435. 10.1016/j.socscimed.2008.02.009.CrossRefPubMed Chapple A, Ziebland S, Hewitson P, McPherson A: What affects the uptake of screening for bowel cancer using a faecal occult blood test (FOBT): a qualitative study. Soc Sci Med. 2008, 66: 2425-2435. 10.1016/j.socscimed.2008.02.009.CrossRefPubMed
17.
go back to reference O’Carroll RE, Foster C, McGeechan G, Sandford K, Ferguson E: The “ick” factor, anticipated regret and willingness to become an organ donor. Health Psychol. 2011, 3: 236-245.CrossRef O’Carroll RE, Foster C, McGeechan G, Sandford K, Ferguson E: The “ick” factor, anticipated regret and willingness to become an organ donor. Health Psychol. 2011, 3: 236-245.CrossRef
18.
go back to reference Gregory TA, Wilson C, Duncan A, Turnbull D, Cole SR, Young G: Demographic, social cognitive and social ecological predictors of intention and participation in screening for colorectal cancer. BMC Public Health. 2011, 11: 38-10.1186/1471-2458-11-38. 10.1186/1471-2458-11-38CrossRefPubMedPubMedCentral Gregory TA, Wilson C, Duncan A, Turnbull D, Cole SR, Young G: Demographic, social cognitive and social ecological predictors of intention and participation in screening for colorectal cancer. BMC Public Health. 2011, 11: 38-10.1186/1471-2458-11-38. 10.1186/1471-2458-11-38CrossRefPubMedPubMedCentral
19.
go back to reference Wardle J, Williamson S, McCaffery K, Sutton S, Taylor T, Edwards R, Atkin W: Increasing attendance at colorectal cancer screening: testing the efficacy of a mailed, psychoeducational intervention in a community sample of older adults. Health Psychol. 2003, 22: 99-105.CrossRefPubMed Wardle J, Williamson S, McCaffery K, Sutton S, Taylor T, Edwards R, Atkin W: Increasing attendance at colorectal cancer screening: testing the efficacy of a mailed, psychoeducational intervention in a community sample of older adults. Health Psychol. 2003, 22: 99-105.CrossRefPubMed
20.
go back to reference Power E, Van Jaarsveld CH, McCaffery K, Miles A, Atkin W, Wardle J: Understanding intentions and action in colorectal cancer screening. Ann Behav Med. 2008, 35: 285-294. 10.1007/s12160-008-9034-y.CrossRefPubMed Power E, Van Jaarsveld CH, McCaffery K, Miles A, Atkin W, Wardle J: Understanding intentions and action in colorectal cancer screening. Ann Behav Med. 2008, 35: 285-294. 10.1007/s12160-008-9034-y.CrossRefPubMed
21.
go back to reference Whitaker KL, Good A, Miles A, Robb K, Wardle J, von Wagner C: Socioeconomic inequalities in colorectal cancer screening uptake: does time perspective play a role?. Health Psychol. 2011, 30: 702-709.CrossRefPubMed Whitaker KL, Good A, Miles A, Robb K, Wardle J, von Wagner C: Socioeconomic inequalities in colorectal cancer screening uptake: does time perspective play a role?. Health Psychol. 2011, 30: 702-709.CrossRefPubMed
22.
go back to reference Hall PA, Fong GT: Temporal self-regulation theory: looking forward. Health Psychol Review. 2010, 4: 83-92. 10.1080/17437199.2010.487180.CrossRef Hall PA, Fong GT: Temporal self-regulation theory: looking forward. Health Psychol Review. 2010, 4: 83-92. 10.1080/17437199.2010.487180.CrossRef
23.
go back to reference Baron RC, Rimer BK, Breslow RA, Coates RJ, Kerner J, Melillo S, Habarta N, Kalra GP, Chattopadhyay S, Wilson KM, Lee NC, Mullen PD, Coughlin SS, Briss PA: Client-directed interventions to increase community demand for breast, cervical, and colorectal cancer screening a systematic review. Am J Prev Med. 2008, 35: S34-S55. 10.1016/j.amepre.2008.04.002.CrossRefPubMed Baron RC, Rimer BK, Breslow RA, Coates RJ, Kerner J, Melillo S, Habarta N, Kalra GP, Chattopadhyay S, Wilson KM, Lee NC, Mullen PD, Coughlin SS, Briss PA: Client-directed interventions to increase community demand for breast, cervical, and colorectal cancer screening a systematic review. Am J Prev Med. 2008, 35: S34-S55. 10.1016/j.amepre.2008.04.002.CrossRefPubMed
24.
go back to reference Smith SK, Trevena L, Simpson JM, Barratt A, Nutbeam D, McCaffery KJ: A decision aid to support informed choices about bowel cancer screening among adults with low education: randomised controlled trial. BMJ. 2010, 341: c5370-10.1136/bmj.c5370.CrossRefPubMedPubMedCentral Smith SK, Trevena L, Simpson JM, Barratt A, Nutbeam D, McCaffery KJ: A decision aid to support informed choices about bowel cancer screening among adults with low education: randomised controlled trial. BMJ. 2010, 341: c5370-10.1136/bmj.c5370.CrossRefPubMedPubMedCentral
25.
go back to reference Libby G, Bray J, Champion J, Brownlee LA, Birrell J, Gorman DR, Crighton EM, Fraser CG, Steele RJ: Pre-notification increases uptake of colorectal cancer screening in all demographic groups: a randomized controlled trial. J Med Screen. 2011, 8: 24-29.CrossRef Libby G, Bray J, Champion J, Brownlee LA, Birrell J, Gorman DR, Crighton EM, Fraser CG, Steele RJ: Pre-notification increases uptake of colorectal cancer screening in all demographic groups: a randomized controlled trial. J Med Screen. 2011, 8: 24-29.CrossRef
26.
go back to reference O’Carroll RE, Dryden J, Hamilton-Barclay T: Increasing organ donor registration using Anticipated Regret – a pilot randomised controlled trial. Health Psychol. 2011, 30: 661-664.CrossRefPubMed O’Carroll RE, Dryden J, Hamilton-Barclay T: Increasing organ donor registration using Anticipated Regret – a pilot randomised controlled trial. Health Psychol. 2011, 30: 661-664.CrossRefPubMed
27.
go back to reference O’Carroll RE, Ferguson E, Hayes PC, Shepherd L: Organ Donation via Anticipated Regret (INORDAR): protocol for a randomised controlled trial. BMC Public Health. 2012, 12: 169-10.1186/1471-2458-12-169. 10.1186/1471-2458-12-169CrossRefPubMedPubMedCentral O’Carroll RE, Ferguson E, Hayes PC, Shepherd L: Organ Donation via Anticipated Regret (INORDAR): protocol for a randomised controlled trial. BMC Public Health. 2012, 12: 169-10.1186/1471-2458-12-169. 10.1186/1471-2458-12-169CrossRefPubMedPubMedCentral
28.
go back to reference Edwards PJ, Roberts IG, Clarke MJ, DiGuiseppi C, Wentz R, Kwan I, Cooper R, Felix L, Pratap S: Methods to increase response rates to postal questionnaires. Cochrane Database Syst Rev. 2007, Issue 2. Art.No.:MR000008 10.1002/14651858.MR000008.pub3 Edwards PJ, Roberts IG, Clarke MJ, DiGuiseppi C, Wentz R, Kwan I, Cooper R, Felix L, Pratap S: Methods to increase response rates to postal questionnaires. Cochrane Database Syst Rev. 2007, Issue 2. Art.No.:MR000008 10.1002/14651858.MR000008.pub3
Metadata
Title
Anticipated regret to increase uptake of colorectal cancer screening in Scotland (ARTICS): study protocol for a randomised controlled trial
Authors
Ronan E O’Carroll
Robert JC Steele
Gillian Libby
Linda Brownlee
Julie A Chambers
Publication date
01-12-2013
Publisher
BioMed Central
Published in
BMC Public Health / Issue 1/2013
Electronic ISSN: 1471-2458
DOI
https://doi.org/10.1186/1471-2458-13-849

Other articles of this Issue 1/2013

BMC Public Health 1/2013 Go to the issue