Skip to main content
Top
Published in: BMC Pediatrics 1/2014

Open Access 01-12-2014 | Research article

Mortality in severely injured children: experiences of a German level 1 trauma center (2002 – 2011)

Authors: Carsten Schoeneberg, Marc Schilling, Judith Keitel, Manuel Burggraf, Bjoern Hussmann, Sven Lendemans

Published in: BMC Pediatrics | Issue 1/2014

Login to get access

Abstract

Background

Trauma in pediatric patients is a major cause of death. This study investigated differences between decedents and survivors. Furthermore, an analysis of preventable and potential preventable trauma deaths was conducted and errors in the acute trauma care were investigated.

Methods

All patients aged less than 16 years with an Injury Severity Score (ISS) ≥ 16 upon primary admission to the hospital between July 2002 and December 2011 were included in this study. Decedents were compared with survivors and an analysis of deceased children for preventable and potential preventable deaths was conducted. The acute trauma care was investigated regarding errors in treatment.

Results

Significant differences were found in Glasgow Coma Scale, Injury Severity Score, Revised Trauma Score, New ISS, Revised Injury Severity Classification, and Trauma and Injury Severity Score. Decedents had a worse head trauma with associated coagulopathy. The overall mortality rate was 13.4%. The majority of death occurred soon after arrival. No long term intensive care unit stay was found.
No preventable but one potential preventable death was analyzed. Most errors occurred in fluid volume management and in a delay of starting the therapy for hemorrhage and coagulopathy.
Prolonged preclinical rescue time and surgery time within the first 24 hours was found.

Conclusions

Head trauma is the determinant factor for mortality in severely injured pediatric patients. Death occurred shortly after arrival and long term intensive care stays might be an exception. In treatment of severely injured children volume management, hemorrhage and coagulopathy management, rescue time, and total surgery time should receive more attention.
Appendix
Available only for authorised users
Literature
1.
go back to reference Statter M, Schuble T, Harris-Rosado M, Liu D, Quinlan K: Targeting pediatric pedestrian injury prevention efforts: teasing the information through spatial analysis. J Trauma. 2011, 71: S511-S516.CrossRefPubMed Statter M, Schuble T, Harris-Rosado M, Liu D, Quinlan K: Targeting pediatric pedestrian injury prevention efforts: teasing the information through spatial analysis. J Trauma. 2011, 71: S511-S516.CrossRefPubMed
2.
go back to reference Potoka DA, Schall LC, Gardner MJ, Stafford PW, Peitzman AB, Ford HR: Impact of pediatric trauma centers on mortality in a statewide system. J Trauma. 2000, 49: 237-245.CrossRefPubMed Potoka DA, Schall LC, Gardner MJ, Stafford PW, Peitzman AB, Ford HR: Impact of pediatric trauma centers on mortality in a statewide system. J Trauma. 2000, 49: 237-245.CrossRefPubMed
3.
go back to reference Potoka DA, Schall LC, Ford HR: Improved functional outcome for severely injured children treated at pediatric trauma centers. J Trauma. 2001, 51: 824-832. discussion 832–4CrossRefPubMed Potoka DA, Schall LC, Ford HR: Improved functional outcome for severely injured children treated at pediatric trauma centers. J Trauma. 2001, 51: 824-832. discussion 832–4CrossRefPubMed
4.
go back to reference Hussmann B, Lefering R, Kauther MD, Ruchholtz S, Moldzio P, Lendemans S: Influence of prehospital volume replacement on outcome in polytraumatized children. Crit Care. 2012, 16: R201-CrossRefPubMedPubMedCentral Hussmann B, Lefering R, Kauther MD, Ruchholtz S, Moldzio P, Lendemans S: Influence of prehospital volume replacement on outcome in polytraumatized children. Crit Care. 2012, 16: R201-CrossRefPubMedPubMedCentral
5.
go back to reference Gruen RL, Jurkovich GJ, McIntyre LK, Foy HM, Maier RV: Patterns of errors contributing to trauma mortality: lessons learned from 2,594 deaths. Ann Surg. 2006, 244: 371-380.PubMedPubMedCentral Gruen RL, Jurkovich GJ, McIntyre LK, Foy HM, Maier RV: Patterns of errors contributing to trauma mortality: lessons learned from 2,594 deaths. Ann Surg. 2006, 244: 371-380.PubMedPubMedCentral
7.
go back to reference Settervall CH, Domingues Cde A, Sousa RM, Nogueira Lde S: Preventable trauma deaths. Rev Saude Publica. 2012, 46: 367-375.CrossRefPubMed Settervall CH, Domingues Cde A, Sousa RM, Nogueira Lde S: Preventable trauma deaths. Rev Saude Publica. 2012, 46: 367-375.CrossRefPubMed
8.
go back to reference Teixeira PG, Inaba K, Hadjizacharia P, Brown C, Salim A, Rhee P, Browder T, Noguchi TT, Demetriades D: Preventable or potentially preventable mortality at a mature trauma center. J Trauma. 2007, 63: 1338-1346. discussion 1346–7CrossRefPubMed Teixeira PG, Inaba K, Hadjizacharia P, Brown C, Salim A, Rhee P, Browder T, Noguchi TT, Demetriades D: Preventable or potentially preventable mortality at a mature trauma center. J Trauma. 2007, 63: 1338-1346. discussion 1346–7CrossRefPubMed
9.
go back to reference Do HQ, Steinmetz J, Rasmussen LS: In-hospital mortality pattern of severely injured children. Injury. 2012, 43: 2060-2064.CrossRefPubMed Do HQ, Steinmetz J, Rasmussen LS: In-hospital mortality pattern of severely injured children. Injury. 2012, 43: 2060-2064.CrossRefPubMed
10.
go back to reference Dykes EH, Spence LJ, Young JG, Bohn DJ, Filler RM, Wesson DE: Preventable pediatric trauma deaths in a metropolitan region. J Pediatr Surg. 1989, 24: 107-110. discussion 110–1CrossRefPubMed Dykes EH, Spence LJ, Young JG, Bohn DJ, Filler RM, Wesson DE: Preventable pediatric trauma deaths in a metropolitan region. J Pediatr Surg. 1989, 24: 107-110. discussion 110–1CrossRefPubMed
11.
go back to reference Diamond IR, Parkin PC, Wales PW, Bohn D, Kreller MA, Dykes EH, McLellan BA, Wesson DE: Preventable pediatric trauma deaths in Ontario: a comparative population-based study. J Trauma. 2009, 66: 1189-1194. discussion 1194–5CrossRefPubMed Diamond IR, Parkin PC, Wales PW, Bohn D, Kreller MA, Dykes EH, McLellan BA, Wesson DE: Preventable pediatric trauma deaths in Ontario: a comparative population-based study. J Trauma. 2009, 66: 1189-1194. discussion 1194–5CrossRefPubMed
12.
go back to reference Esposito TJ, Sanddal ND, Dean JM, Hansen JD, Reynolds SA, Battan K: Analysis of preventable pediatric trauma deaths and inappropriate trauma care in Montana. J Trauma. 1999, 47: 243-251. discussion 251–3CrossRefPubMed Esposito TJ, Sanddal ND, Dean JM, Hansen JD, Reynolds SA, Battan K: Analysis of preventable pediatric trauma deaths and inappropriate trauma care in Montana. J Trauma. 1999, 47: 243-251. discussion 251–3CrossRefPubMed
14.
go back to reference Reason JT: Human Error. 1990, Cambridge [England], New York: Cambridge University PressCrossRef Reason JT: Human Error. 1990, Cambridge [England], New York: Cambridge University PressCrossRef
16.
go back to reference Spahn DR, Bouillon B, Cerny V, Coats TJ, Duranteau J, Fernández-Mondéjar E, Filipescu D, Hunt BJ, Komadina R, Nardi G, Neugebauer E, Ozier Y, Riddez L, Schultz A, Vincent J, Rossaint R: Management of bleeding and coagulopathy following major trauma: an updated European guideline. Crit Care. 2013, 17: R76-CrossRefPubMedPubMedCentral Spahn DR, Bouillon B, Cerny V, Coats TJ, Duranteau J, Fernández-Mondéjar E, Filipescu D, Hunt BJ, Komadina R, Nardi G, Neugebauer E, Ozier Y, Riddez L, Schultz A, Vincent J, Rossaint R: Management of bleeding and coagulopathy following major trauma: an updated European guideline. Crit Care. 2013, 17: R76-CrossRefPubMedPubMedCentral
17.
go back to reference Schoeneberg C, Schilling M, Keitel J, Kauther MD, Burggraf M, Hussmann B, Lendemans S: TraumaNetwork, trauma registry of the DGU (R), whitebook, S3 guideline on treatment of polytrauma/severe injuries - an approach for validation by a retrospective analysis of 2304 patients (2002–2011) of a level 1 trauma centre. Zentralbl Chir. 2014, epub ahead of print Schoeneberg C, Schilling M, Keitel J, Kauther MD, Burggraf M, Hussmann B, Lendemans S: TraumaNetwork, trauma registry of the DGU (R), whitebook, S3 guideline on treatment of polytrauma/severe injuries - an approach for validation by a retrospective analysis of 2304 patients (2002–2011) of a level 1 trauma centre. Zentralbl Chir. 2014, epub ahead of print
18.
go back to reference MacKenzie EJ: Review of evidence regarding trauma system effectiveness resulting from panel studies. J Trauma. 1999, 47: S34-S41.CrossRefPubMed MacKenzie EJ: Review of evidence regarding trauma system effectiveness resulting from panel studies. J Trauma. 1999, 47: S34-S41.CrossRefPubMed
19.
go back to reference Shackford SR, Hollingsworth-Fridlund P, McArdle M, Eastman AB: Assuring quality in a trauma system–the Medical Audit Committee: composition, cost, and results. J Trauma. 1987, 27: 866-875.CrossRefPubMed Shackford SR, Hollingsworth-Fridlund P, McArdle M, Eastman AB: Assuring quality in a trauma system–the Medical Audit Committee: composition, cost, and results. J Trauma. 1987, 27: 866-875.CrossRefPubMed
21.
go back to reference Courville XF, Koval KJ, Carney BT, Spratt KF: Early prediction of posttraumatic in-hospital mortality in pediatric patients. J Pediatr Orthop. 2009, 29: 439-444.CrossRefPubMed Courville XF, Koval KJ, Carney BT, Spratt KF: Early prediction of posttraumatic in-hospital mortality in pediatric patients. J Pediatr Orthop. 2009, 29: 439-444.CrossRefPubMed
22.
go back to reference Diamond IR, Parkin PC, Wales PW, Bohn D, Kreller MA, Dykes EH, McLellan BA, Wesson DE: Pediatric blunt and penetrating trauma deaths in Ontario: a population-based study. J Pediatr Surg. 2009, 44: 981-986.CrossRefPubMed Diamond IR, Parkin PC, Wales PW, Bohn D, Kreller MA, Dykes EH, McLellan BA, Wesson DE: Pediatric blunt and penetrating trauma deaths in Ontario: a population-based study. J Pediatr Surg. 2009, 44: 981-986.CrossRefPubMed
23.
go back to reference Kipfmueller F, Wyen H, Borgman MA, Spinella PC, Wirth S, Maegele M: Epidemiology, risk stratification and outcome of severe pediatric trauma. Klin Padiatr. 2013, 225: 34-40.PubMed Kipfmueller F, Wyen H, Borgman MA, Spinella PC, Wirth S, Maegele M: Epidemiology, risk stratification and outcome of severe pediatric trauma. Klin Padiatr. 2013, 225: 34-40.PubMed
24.
go back to reference Narotam PK, Burjonrappa SC, Raynor SC, Rao M, Taylon C: Cerebral oxygenation in major pediatric trauma: its relevance to trauma severity and outcome. J Pediatr Surg. 2006, 41: 505-513.CrossRefPubMed Narotam PK, Burjonrappa SC, Raynor SC, Rao M, Taylon C: Cerebral oxygenation in major pediatric trauma: its relevance to trauma severity and outcome. J Pediatr Surg. 2006, 41: 505-513.CrossRefPubMed
25.
go back to reference Chiaretti A, Pezzotti P, Mestrovic J, Piastra M, Polidori G, Storti S, Velardi F, Di Rocco C: The influence of hemocoagulative disorders on the outcome of children with head injury. Pediatr Neurosurg. 2001, 34: 131-137.CrossRefPubMed Chiaretti A, Pezzotti P, Mestrovic J, Piastra M, Polidori G, Storti S, Velardi F, Di Rocco C: The influence of hemocoagulative disorders on the outcome of children with head injury. Pediatr Neurosurg. 2001, 34: 131-137.CrossRefPubMed
26.
go back to reference Affonseca CA, Carvalho , Luis Fernando A, Guerra SD, Ferreira AR, Goulart , Eugenio MA: Coagulation disorder in children and adolescents with moderate to severe traumatic brain injury. J Pediatr (Rio J). 2007, 83: 274-282. Affonseca CA, Carvalho , Luis Fernando A, Guerra SD, Ferreira AR, Goulart , Eugenio MA: Coagulation disorder in children and adolescents with moderate to severe traumatic brain injury. J Pediatr (Rio J). 2007, 83: 274-282.
27.
go back to reference Pathak A, Dutta S, Marwaha N, Singh D, Varma N, Mathuriya SN: Change in tissue thromboplastin content of brain following trauma. Neurol India. 2005, 53: 178-182.CrossRefPubMed Pathak A, Dutta S, Marwaha N, Singh D, Varma N, Mathuriya SN: Change in tissue thromboplastin content of brain following trauma. Neurol India. 2005, 53: 178-182.CrossRefPubMed
28.
go back to reference Joseph B, Aziz H, Zangbar B, Kulvatunyou N, Pandit V, O'Keeffe T, Tang A, Wynne J, Friese RS, Rhee P: Acquired coagulopathy of traumatic brain injury defined by routine laboratory tests: which laboratory values matter?. J Trauma Acute Care Surg. 2014, 76: 121-125.CrossRefPubMed Joseph B, Aziz H, Zangbar B, Kulvatunyou N, Pandit V, O'Keeffe T, Tang A, Wynne J, Friese RS, Rhee P: Acquired coagulopathy of traumatic brain injury defined by routine laboratory tests: which laboratory values matter?. J Trauma Acute Care Surg. 2014, 76: 121-125.CrossRefPubMed
29.
go back to reference Carrick MM, Tyroch AH, Youens CA, Handley T: Subsequent development of thrombocytopenia and coagulopathy in moderate and severe head injury: support for serial laboratory examination. J Trauma. 2005, 58: 725-729. discussion 729–30CrossRefPubMed Carrick MM, Tyroch AH, Youens CA, Handley T: Subsequent development of thrombocytopenia and coagulopathy in moderate and severe head injury: support for serial laboratory examination. J Trauma. 2005, 58: 725-729. discussion 729–30CrossRefPubMed
30.
go back to reference Jung J, Eo E, Ahn K, Noh H, Cheon Y: Initial base deficit as predictors for mortality and transfusion requirement in the severe pediatric trauma except brain injury. Pediatr Emerg Care. 2009, 25: 579-581.CrossRefPubMed Jung J, Eo E, Ahn K, Noh H, Cheon Y: Initial base deficit as predictors for mortality and transfusion requirement in the severe pediatric trauma except brain injury. Pediatr Emerg Care. 2009, 25: 579-581.CrossRefPubMed
31.
go back to reference Hindy-Francois C, Meyer P, Blanot S, Marque S, Sabourdin N, Carli P, Orliaguet G: Admission base deficit as a long-term prognostic factor in severe pediatric trauma patients. J Trauma. 2009, 67: 1272-1277.CrossRefPubMed Hindy-Francois C, Meyer P, Blanot S, Marque S, Sabourdin N, Carli P, Orliaguet G: Admission base deficit as a long-term prognostic factor in severe pediatric trauma patients. J Trauma. 2009, 67: 1272-1277.CrossRefPubMed
32.
go back to reference Cooke WH, Salinas J, Convertino VA, Ludwig DA, Hinds D, Duke JH, Moore FA, Holcomb JB: Heart rate variability and its association with mortality in prehospital trauma patients. J Trauma. 2006, 60: 363-370. discussion 370CrossRefPubMed Cooke WH, Salinas J, Convertino VA, Ludwig DA, Hinds D, Duke JH, Moore FA, Holcomb JB: Heart rate variability and its association with mortality in prehospital trauma patients. J Trauma. 2006, 60: 363-370. discussion 370CrossRefPubMed
33.
go back to reference Walia S, Sutcliffe AJ: The relationship between blood glucose, mean arterial pressure and outcome after severe head injury: an observational study. Injury. 2002, 33: 339-344.CrossRefPubMed Walia S, Sutcliffe AJ: The relationship between blood glucose, mean arterial pressure and outcome after severe head injury: an observational study. Injury. 2002, 33: 339-344.CrossRefPubMed
34.
go back to reference Baker CC, Oppenheimer L, Stephens B, Lewis FR, Trunkey DD: Epidemiology of trauma deaths. Am J Surg. 1980, 140: 144-150.CrossRefPubMed Baker CC, Oppenheimer L, Stephens B, Lewis FR, Trunkey DD: Epidemiology of trauma deaths. Am J Surg. 1980, 140: 144-150.CrossRefPubMed
35.
go back to reference Pape H, Grimme K, van Griensven M, Sott AH, Giannoudis P, Morley J, Roise O, Ellingsen E, Hildebrand F, Wiese B, Krettek C: Impact of intramedullary instrumentation versus damage control for femoral fractures on immunoinflammatory parameters: prospective randomized analysis by the EPOFF Study Group. J Trauma. 2003, 55: 7-13.CrossRefPubMed Pape H, Grimme K, van Griensven M, Sott AH, Giannoudis P, Morley J, Roise O, Ellingsen E, Hildebrand F, Wiese B, Krettek C: Impact of intramedullary instrumentation versus damage control for femoral fractures on immunoinflammatory parameters: prospective randomized analysis by the EPOFF Study Group. J Trauma. 2003, 55: 7-13.CrossRefPubMed
36.
go back to reference Schoeneberg C, Schilling M, Burggraf M, Fochtmann U, Lendemans S: Reduction in mortality in severely injured patients following the introduction of the “Treatment of patients with severe and multiple injuries” guideline of the German society of trauma surgery–a retrospective analysis of a level 1 trauma center (2010–2012). Injury. 2014, 45: 635-638.CrossRefPubMed Schoeneberg C, Schilling M, Burggraf M, Fochtmann U, Lendemans S: Reduction in mortality in severely injured patients following the introduction of the “Treatment of patients with severe and multiple injuries” guideline of the German society of trauma surgery–a retrospective analysis of a level 1 trauma center (2010–2012). Injury. 2014, 45: 635-638.CrossRefPubMed
Metadata
Title
Mortality in severely injured children: experiences of a German level 1 trauma center (2002 – 2011)
Authors
Carsten Schoeneberg
Marc Schilling
Judith Keitel
Manuel Burggraf
Bjoern Hussmann
Sven Lendemans
Publication date
01-12-2014
Publisher
BioMed Central
Published in
BMC Pediatrics / Issue 1/2014
Electronic ISSN: 1471-2431
DOI
https://doi.org/10.1186/1471-2431-14-194

Other articles of this Issue 1/2014

BMC Pediatrics 1/2014 Go to the issue