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Current Oral Health Reports
Published in: Current Oral Health Reports 1/2020

01-03-2020 | Lung Cancer | Host Parasite Interactions in Periodontal Disease (C Genco and D Kinane, Section Editors)

The Oral Microbiome and Lung Diseases

Authors: Chan Y. Pu, Mukund Seshadri, Sunita Manuballa, Sai Yendamuri

Published in: Current Oral Health Reports | Issue 1/2020

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Abstract

Purpose of Review

The understanding of the human microbiome, especially of the oral cavity, has expanded exponentially since the advent of 16 rRNA PCR gene sequencing. Since the respiratory tract starts from the oral cavity and ends in the lung, study of the relationship between the oral microbiota and the lungs will allow us to understand the changes in lung disease compared with healthy state.

Recent Findings

The oral and lung microbiota were found to be similar, but the oral microbiota had greater diversity. The oral cavity especially the dorsal tongue was found to be a reservoir for bacteria causing pneumonia and chronic lung infection in cystic fibrosis. Oral and lung infections seem to all share the similar pathogenesis of oral microbiota dysbiosis. Certain oral bacteria were found to be potential biomarkers for lung cancer.

Summary

Improvement in oral health is important especially in the management of lung diseases with infectious etiology. Oral microbiota can serve as biomarkers for diseases especially in lung cancer.
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Metadata
Title
The Oral Microbiome and Lung Diseases
Authors
Chan Y. Pu
Mukund Seshadri
Sunita Manuballa
Sai Yendamuri
Publication date
01-03-2020

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