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Current Oral Health Reports
Published in: Current Oral Health Reports 1/2019

Open Access 01-03-2019 | Leukoplakia | Systemic Diseases (N Buduneli, Section Editor)

Oral Leukoplakia: Present Views on Diagnosis, Management, Communication with Patients, and Research

Author: Isaäc van der Waal

Published in: Current Oral Health Reports | Issue 1/2019

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Abstract

Leukoplakia is a predominantly white lesion of the oral mucosa that carries an increased risk of malignant transformation.

Purpose of Review

(1) To provide insight into the difficulties in arriving at a proper diagnosis, (2) to evaluate the latest research on (bio) markers that may have predictive value with regard to the risk of malignant transformation, and (3) to evaluate the latest research on how patients with oral leukoplakia should be managed.

Recent Findings

Research on oral leukoplakia is still very much hampered, mainly because of the rather poor definition. No new (bio)markers have become available that reliably would predict malignant transformation. Surgical and nonsurgical treatments have still not yet been proven to be effective in preventing such transformation.

Summary

Only after having solved the shortcomings in the definition and the lack of uniform reporting problem proper, randomized controlled studies on the various aspects of oral leukoplakia can be performed.
Literature
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Brouns ER, Baart JA, Bloemena E, Karagozoglu H, van der Waal I. The relevance of uniform reporting in oral leukoplakia: definition, certainty factor and staging based on experience with 275 patients. Med Oral PatoRl Oral Cir Bucal. 2013;18(1):e19–26.CrossRef
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Metadata
Title
Oral Leukoplakia: Present Views on Diagnosis, Management, Communication with Patients, and Research
Author
Isaäc van der Waal
Publication date
01-03-2019
Publisher
Springer International Publishing
Published in
Current Oral Health Reports / Issue 1/2019
Electronic ISSN: 2196-3002
DOI
https://doi.org/10.1007/s40496-019-0204-8

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Correction

Correction to: Association Between Periodontal Diseases and Adverse Gestation Outcomes: a Review of the Current Literature