Skip to main content
Top
Published in: Applied Health Economics and Health Policy 3/2017

Open Access 01-06-2017 | Practical Application

Geographic Resource Allocation Based on Cost Effectiveness: An Application to Malaria Policy

Authors: Tom L. Drake, Yoel Lubell, Shwe Sin Kyaw, Angela Devine, Myat Phone Kyaw, Nicholas P. J. Day, Frank M. Smithuis, Lisa J. White

Published in: Applied Health Economics and Health Policy | Issue 3/2017

Login to get access

Abstract

Healthcare services are often provided to a country as a whole, though in many cases the available resources can be more effectively targeted to specific geographically defined populations. In the case of malaria, risk is highly geographically heterogeneous, and many interventions, such as insecticide-treated bed nets and malaria community health workers, can be targeted to populations in a way that maximises impact for the resources available. This paper describes a framework for geographically targeted budget allocation based on the principles of cost-effectiveness analysis and applied to priority setting in malaria control and elimination. The approach can be used with any underlying model able to estimate intervention costs and effects given relevant local data. Efficient geographic targeting of core malaria interventions could significantly increase the impact of the resources available, accelerating progress towards elimination. These methods may also be applicable to priority setting in other disease areas.
Footnotes
1
A standard combinatorial optimisation of placing objects of different weights into a knapsack.
 
Literature
1.
go back to reference Alonso PL, Tanner M. Public health challenges and prospects for malaria control and elimination. Nat Med. 2013;19:150–5.CrossRefPubMed Alonso PL, Tanner M. Public health challenges and prospects for malaria control and elimination. Nat Med. 2013;19:150–5.CrossRefPubMed
2.
3.
go back to reference Goodman C, Coleman P, Mills A. Cost-effectiveness of malaria control in sub-Saharan Africa. Lancet. 1999;354:378–85.CrossRefPubMed Goodman C, Coleman P, Mills A. Cost-effectiveness of malaria control in sub-Saharan Africa. Lancet. 1999;354:378–85.CrossRefPubMed
4.
go back to reference Goodman CA, Mills AJ. The evidence base on the cost-effectiveness of malaria control measures in Africa. Health Policy Plan. 1999;14:301–12.CrossRefPubMed Goodman CA, Mills AJ. The evidence base on the cost-effectiveness of malaria control measures in Africa. Health Policy Plan. 1999;14:301–12.CrossRefPubMed
5.
go back to reference Lubell Y, Riewpaiboon A, Dondorp AM, et al. Cost-effectiveness of parenteral artesunate for treating children with severe malaria in sub-Saharan Africa. Bull World Health Organ. 2011;89:504–12.CrossRefPubMedPubMedCentral Lubell Y, Riewpaiboon A, Dondorp AM, et al. Cost-effectiveness of parenteral artesunate for treating children with severe malaria in sub-Saharan Africa. Bull World Health Organ. 2011;89:504–12.CrossRefPubMedPubMedCentral
6.
go back to reference Shillcutt S, Morel C, Goodman C, Coleman P, Bell D, Whitty CJ, Mills A. Cost-effectiveness of malaria diagnostic methods in sub-Saharan Africa in an era of combination therapy. Bull World Health Organ. 2008;86:101–10.CrossRefPubMed Shillcutt S, Morel C, Goodman C, Coleman P, Bell D, Whitty CJ, Mills A. Cost-effectiveness of malaria diagnostic methods in sub-Saharan Africa in an era of combination therapy. Bull World Health Organ. 2008;86:101–10.CrossRefPubMed
7.
go back to reference Mangham-Jefferies L, Wiseman V, Achonduh OA, Drake TL, Cundill B, Onwujekwe O, Mbacham W. Economic evaluation of a cluster randomized trial of interventions to improve health workers’ practice in diagnosing and treating uncomplicated malaria in Cameroon. Value Health. 2014;17:783–91.CrossRefPubMed Mangham-Jefferies L, Wiseman V, Achonduh OA, Drake TL, Cundill B, Onwujekwe O, Mbacham W. Economic evaluation of a cluster randomized trial of interventions to improve health workers’ practice in diagnosing and treating uncomplicated malaria in Cameroon. Value Health. 2014;17:783–91.CrossRefPubMed
8.
go back to reference Lubell Y, Reyburn H, Mbakilwa H, Mwangi R, Chonya K, Whitty CJM, Mills A. The cost-effectiveness of parasitologic diagnosis for malaria-suspected patients in an era of combination therapy. Am J Trop Med Hyg. 2007;77:128–32.PubMed Lubell Y, Reyburn H, Mbakilwa H, Mwangi R, Chonya K, Whitty CJM, Mills A. The cost-effectiveness of parasitologic diagnosis for malaria-suspected patients in an era of combination therapy. Am J Trop Med Hyg. 2007;77:128–32.PubMed
9.
go back to reference Gething PW, Patil AP, Smith DL, Guerra CA, Elyazar IR, Johnston GL, Tatem AJ, Hay SI. A new world malaria map: Plasmodium falciparum endemicity in 2010. Malar J. 2011;10:378.CrossRefPubMedPubMedCentral Gething PW, Patil AP, Smith DL, Guerra CA, Elyazar IR, Johnston GL, Tatem AJ, Hay SI. A new world malaria map: Plasmodium falciparum endemicity in 2010. Malar J. 2011;10:378.CrossRefPubMedPubMedCentral
10.
11.
12.
go back to reference Bejon P, Williams TN, Nyundo C, et al. A micro-epidemiological analysis of febrile malaria in Coastal Kenya showing hotspots within hotspots. eLife. 2014;3:e02130.CrossRefPubMedPubMedCentral Bejon P, Williams TN, Nyundo C, et al. A micro-epidemiological analysis of febrile malaria in Coastal Kenya showing hotspots within hotspots. eLife. 2014;3:e02130.CrossRefPubMedPubMedCentral
13.
go back to reference Wesolowski A, Eagle N, Tatem AJ, Smith DL, Noor AM, Snow RW, Buckee CO. Quantifying the impact of human mobility on malaria. Science. 2012;338:267–70.CrossRefPubMedPubMedCentral Wesolowski A, Eagle N, Tatem AJ, Smith DL, Noor AM, Snow RW, Buckee CO. Quantifying the impact of human mobility on malaria. Science. 2012;338:267–70.CrossRefPubMedPubMedCentral
14.
go back to reference Pindolia DK, Garcia AJ, Huang Z, Smith DL, Alegana VA, Noor AM, Snow RW, Tatem AJ. The demographics of human and malaria movement and migration patterns in East Africa. Malar J. 2013;12:397.CrossRefPubMedPubMedCentral Pindolia DK, Garcia AJ, Huang Z, Smith DL, Alegana VA, Noor AM, Snow RW, Tatem AJ. The demographics of human and malaria movement and migration patterns in East Africa. Malar J. 2013;12:397.CrossRefPubMedPubMedCentral
15.
go back to reference Bousema T, Stevenson J, Baidjoe A, et al. The impact of hotspot-targeted interventions on malaria transmission: study protocol for a cluster-randomized controlled trial. Trials. 2013;14:36.CrossRefPubMedPubMedCentral Bousema T, Stevenson J, Baidjoe A, et al. The impact of hotspot-targeted interventions on malaria transmission: study protocol for a cluster-randomized controlled trial. Trials. 2013;14:36.CrossRefPubMedPubMedCentral
16.
go back to reference Wangdi K, Banwell C, Gatton ML, Kelly GC, Namgay R, Clements ACA. Development and evaluation of a spatial decision support system for malaria elimination in Bhutan. Malar J. 2016;15:180.CrossRefPubMedPubMedCentral Wangdi K, Banwell C, Gatton ML, Kelly GC, Namgay R, Clements ACA. Development and evaluation of a spatial decision support system for malaria elimination in Bhutan. Malar J. 2016;15:180.CrossRefPubMedPubMedCentral
17.
go back to reference Marston L, Kelly GC, Hale E, Clements ACA, Hodge A, Jimenez-Soto E. Cost analysis of the development and implementation of a spatial decision support system for malaria elimination in Solomon Islands. Malar J. 2014;13:325.CrossRefPubMedPubMedCentral Marston L, Kelly GC, Hale E, Clements ACA, Hodge A, Jimenez-Soto E. Cost analysis of the development and implementation of a spatial decision support system for malaria elimination in Solomon Islands. Malar J. 2014;13:325.CrossRefPubMedPubMedCentral
18.
go back to reference Anderson S-J, Cherutich P, Kilonzo N, et al. Maximising the effect of combination HIV prevention through prioritisation of the people and places in greatest need: a modelling study. Lancet. 2014;384:249–56.CrossRefPubMed Anderson S-J, Cherutich P, Kilonzo N, et al. Maximising the effect of combination HIV prevention through prioritisation of the people and places in greatest need: a modelling study. Lancet. 2014;384:249–56.CrossRefPubMed
19.
go back to reference Drake TL, Kyaw SS, Kyaw MP, Smithuis FM, Day NP, White LJ, Lubell Y. Cost effectiveness and resource allocation of Plasmodium falciparum malaria control in Myanmar: a modelling analysis of bed nets and community health workers. Malar J. 2015;14:376.CrossRefPubMedPubMedCentral Drake TL, Kyaw SS, Kyaw MP, Smithuis FM, Day NP, White LJ, Lubell Y. Cost effectiveness and resource allocation of Plasmodium falciparum malaria control in Myanmar: a modelling analysis of bed nets and community health workers. Malar J. 2015;14:376.CrossRefPubMedPubMedCentral
20.
go back to reference Walker PGT, Griffin JT, Ferguson NM, Ghani AC. Estimating the most efficient allocation of interventions to achieve reductions in Plasmodium falciparum malaria burden and transmission in Africa: a modelling study. Lancet Glob Health. 2016;4:e474–84.CrossRefPubMed Walker PGT, Griffin JT, Ferguson NM, Ghani AC. Estimating the most efficient allocation of interventions to achieve reductions in Plasmodium falciparum malaria burden and transmission in Africa: a modelling study. Lancet Glob Health. 2016;4:e474–84.CrossRefPubMed
21.
go back to reference Drummond MF, Sculpher MJ, Torrance GW. Methods for the economic evaluation of health care programs. Oxford: Oxford University Press; 2005. Drummond MF, Sculpher MJ, Torrance GW. Methods for the economic evaluation of health care programs. Oxford: Oxford University Press; 2005.
22.
go back to reference Briggs A. Probabilistic analysis of cost-effectiveness models: statistical representation of parameter uncertainty. Value Health. 2005;8:1–2.CrossRefPubMed Briggs A. Probabilistic analysis of cost-effectiveness models: statistical representation of parameter uncertainty. Value Health. 2005;8:1–2.CrossRefPubMed
23.
go back to reference Gray AM, Clarke PM, Wolstenholme JL, Wordsworth S. Applied methods of cost-effectiveness analysis in healthcare. Oxford: Oxford University Press; 2011. Gray AM, Clarke PM, Wolstenholme JL, Wordsworth S. Applied methods of cost-effectiveness analysis in healthcare. Oxford: Oxford University Press; 2011.
24.
go back to reference Weinstein M, Zeckhauser R. Critical ratios and efficient allocation. J Public Econ. 1973;2:147–57.CrossRef Weinstein M, Zeckhauser R. Critical ratios and efficient allocation. J Public Econ. 1973;2:147–57.CrossRef
26.
go back to reference Meyer-Rath G, Over M. HIV treatment as prevention: modelling the cost of antiretroviral treatment—state of the art and future directions. PLOS Med. 2012;9:e1001247.CrossRefPubMedPubMedCentral Meyer-Rath G, Over M. HIV treatment as prevention: modelling the cost of antiretroviral treatment—state of the art and future directions. PLOS Med. 2012;9:e1001247.CrossRefPubMedPubMedCentral
27.
go back to reference Lépine A, Chandrashekar S, Shetty G, Vickerman P, Bradley J, Alary M, Moses S, CHARME India Group, Vassall A. What determines HIV prevention costs at scale? Evidence from the Avahan programme in India. Health Econ. 2016;25(Suppl 1):67–82.CrossRefPubMedPubMedCentral Lépine A, Chandrashekar S, Shetty G, Vickerman P, Bradley J, Alary M, Moses S, CHARME India Group, Vassall A. What determines HIV prevention costs at scale? Evidence from the Avahan programme in India. Health Econ. 2016;25(Suppl 1):67–82.CrossRefPubMedPubMedCentral
28.
go back to reference Bennett JP, Saaty TL. Knapsack allocation of multiple resources in benefit-cost analysis by way of the analytic hierarchy process. Math Comput Model. 1993;17:55–72.CrossRef Bennett JP, Saaty TL. Knapsack allocation of multiple resources in benefit-cost analysis by way of the analytic hierarchy process. Math Comput Model. 1993;17:55–72.CrossRef
29.
go back to reference Birch S, Gafni A. Changing the problem to fit the solution: Johannesson and Weinstein’s (mis) application of economics to real world problems. J Health Econ. 1993;12:469–76.CrossRefPubMed Birch S, Gafni A. Changing the problem to fit the solution: Johannesson and Weinstein’s (mis) application of economics to real world problems. J Health Econ. 1993;12:469–76.CrossRefPubMed
30.
go back to reference Johannesson M, Weinstein MC. On the decision rules of cost-effectiveness analysis. J Health Econ. 1993;12:459–67.CrossRefPubMed Johannesson M, Weinstein MC. On the decision rules of cost-effectiveness analysis. J Health Econ. 1993;12:459–67.CrossRefPubMed
31.
go back to reference Gafni A, Birch S. Incremental cost-effectiveness ratios (ICERs): the silence of the lambda. Soc Sci Med. 2006;62:2091–100.CrossRefPubMed Gafni A, Birch S. Incremental cost-effectiveness ratios (ICERs): the silence of the lambda. Soc Sci Med. 2006;62:2091–100.CrossRefPubMed
32.
go back to reference Chalabi Z, Epstein D, McKenna C, Claxton K. Uncertainty and value of information when allocating resources within and between healthcare programmes. Eur J Oper Res. 2008;191:530–9.CrossRef Chalabi Z, Epstein D, McKenna C, Claxton K. Uncertainty and value of information when allocating resources within and between healthcare programmes. Eur J Oper Res. 2008;191:530–9.CrossRef
33.
go back to reference McKenna C, Chalabi Z, Epstein D, Claxton K. Budgetary policies and available actions: a generalisation of decision rules for allocation and research decisions. J Health Econ. 2010;29:170–81.CrossRefPubMed McKenna C, Chalabi Z, Epstein D, Claxton K. Budgetary policies and available actions: a generalisation of decision rules for allocation and research decisions. J Health Econ. 2010;29:170–81.CrossRefPubMed
34.
go back to reference Lo NC, Lai Y-S, Karagiannis-Voules D-A, Bogoch II, Coulibaly JT, Bendavid E, Utzinger J, Vounatsou P, Andrews JR. Assessment of global guidelines for preventive chemotherapy against schistosomiasis and soil-transmitted helminthiasis: a cost-effectiveness modelling study. Lancet Infect Dis. 2016;16:1065–75.CrossRefPubMed Lo NC, Lai Y-S, Karagiannis-Voules D-A, Bogoch II, Coulibaly JT, Bendavid E, Utzinger J, Vounatsou P, Andrews JR. Assessment of global guidelines for preventive chemotherapy against schistosomiasis and soil-transmitted helminthiasis: a cost-effectiveness modelling study. Lancet Infect Dis. 2016;16:1065–75.CrossRefPubMed
35.
go back to reference Verguet S, Laxminarayan R, Jamison DT. Universal public finance of tuberculosis treatment in India: an extended cost-effectiveness analysis. Health Econ. 2015;24:318–32.CrossRefPubMed Verguet S, Laxminarayan R, Jamison DT. Universal public finance of tuberculosis treatment in India: an extended cost-effectiveness analysis. Health Econ. 2015;24:318–32.CrossRefPubMed
36.
go back to reference Cookson R, Drummond M, Weatherly H. Explicit incorporation of equity considerations into economic evaluation of public health interventions. Health Econ Policy Law. 2009;4:231–45.CrossRefPubMed Cookson R, Drummond M, Weatherly H. Explicit incorporation of equity considerations into economic evaluation of public health interventions. Health Econ Policy Law. 2009;4:231–45.CrossRefPubMed
Metadata
Title
Geographic Resource Allocation Based on Cost Effectiveness: An Application to Malaria Policy
Authors
Tom L. Drake
Yoel Lubell
Shwe Sin Kyaw
Angela Devine
Myat Phone Kyaw
Nicholas P. J. Day
Frank M. Smithuis
Lisa J. White
Publication date
01-06-2017
Publisher
Springer International Publishing
Published in
Applied Health Economics and Health Policy / Issue 3/2017
Print ISSN: 1175-5652
Electronic ISSN: 1179-1896
DOI
https://doi.org/10.1007/s40258-017-0305-2

Other articles of this Issue 3/2017

Applied Health Economics and Health Policy 3/2017 Go to the issue