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Journal of Diabetes & Metabolic Disorders

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01-06-2021 | Diabetes | Research article

The effect of physical activity on total homocysteine concentrations and cardiovascular risk in older Brazilian adults with type 2 diabetes

Authors: José Jonas de Oliveira, Alexandre de Souza e Silva, Anna Gabriela Silva Vilela Ribeiro, Carolina Gabriela Reis Barbosa, Jasiele Aparecida de Oliveira Silva, Annie Guimarães Pontes, João Paulo Estevam Batista, Adriana Pertille

Published in: Journal of Diabetes & Metabolic Disorders | Issue 1/2021

Abstract

A low level of physical activity has a potential association with high levels of homocysteine, which implies an increased chance of older adults with type 2 diabetes mellitus developing cardiovascular disease (CVD). However, the effects of physical activity on homocysteine levels have been poorly explored in the literature. Therefore, this study compared homocysteine levels and cardiovascular risk among physically active and inactive older women with type 2 diabetes mellitus. Fifty-nine women with type 2 diabetes mellitus, between 60 and 91 years old, were evaluated. The level of physical activity was assessed using the International Physical Activity Questionnaire (IPAQ) long version to identify active and inactive older women. Blood samples were collected and anthropometric, body composition, and blood pressure measurements were performed to determine homocysteine levels and cardiovascular risk. The results demonstrated that active older women with type 2 diabetes mellitus have lower homocysteine values (F = 17.79, p < 0.001, ηp² = 0.238), cardiovascular risk scores (F = 15.84, p = p < 0.001, ηp² = 0.217), and waist circumferences (F = 2.95, p = 0.013, ηp² = 0.049) when compared with inactive older women. It was concluded that there was a difference in the levels of homocysteine, cardiovascular risk, and waist circumference between active and inactive older women with type 2 diabetes. Active older women are less likely to have cardiovascular risk than inactive older women.

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Title: The effect of physical activity on total homocysteine concentrations and cardiovascular risk in older Brazilian adults with type 2 diabetes
Authors: José Jonas de Oliveira
Alexandre de Souza e Silva
Anna Gabriela Silva Vilela Ribeiro
Carolina Gabriela Reis Barbosa
Jasiele Aparecida de Oliveira Silva
Annie Guimarães Pontes
João Paulo Estevam Batista
Adriana Pertille
Publication date: 01-06-2021
Publisher: Springer International Publishing
Keywords: Diabetes
Type 2 Diabetes
Published in: Journal of Diabetes & Metabolic Disorders / Issue 1/2021
Electronic ISSN: 2251-6581
DOI: https://doi.org/10.1007/s40200-021-00759-6

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