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Published in: Current Anesthesiology Reports 1/2015

01-03-2015 | Perioperative Delirium (JM Leung, Section Editor)

Postoperative Delirium: A Review of Risk Factors and Tools of Prediction

Authors: Katie J. Schenning, Stacie G. Deiner

Published in: Current Anesthesiology Reports | Issue 1/2015

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Abstract

Over one-third of the surgeries in the United States are performed on patients aged 65 and older, and delirium is one of the most common postoperative complications in this population. Postoperative delirium is a heterogeneous disorder, and as such it is not surprising that the reported predisposing and precipitating factors are widely variable. Knowledge of the risk factors that predict postoperative delirium will aid in early identification of patients at highest risk in order to allow targeted use of resources including geriatric consults, specialized units, and nonpharmacologic interventions.
Literature
1.
go back to reference Parikh SS, Chung F. Postoperative delirium in the elderly. Anesth Analg. 1995;80:1223–32.PubMed Parikh SS, Chung F. Postoperative delirium in the elderly. Anesth Analg. 1995;80:1223–32.PubMed
2.
go back to reference van der Mast RC, Roest FH. Delirium after cardiac surgery: a critical review. J Psychosom Res. 1996;41:13–30.CrossRefPubMed van der Mast RC, Roest FH. Delirium after cardiac surgery: a critical review. J Psychosom Res. 1996;41:13–30.CrossRefPubMed
3.
go back to reference Demeure MJ, Fain MJ. The elderly surgical patient and postoperative delirium. J Am Coll Surg. 2006;203:752–7.CrossRefPubMed Demeure MJ, Fain MJ. The elderly surgical patient and postoperative delirium. J Am Coll Surg. 2006;203:752–7.CrossRefPubMed
4.
go back to reference Kazmierski J, Kowman M, Banach M, et al. The use of DSM-IV and ICD-10 criteria and diagnostic scales for delirium among cardiac surgery patients: results from the IPDACS study. J Neuropsychiatr Clin Neurosci. 2010;22:426–32.CrossRef Kazmierski J, Kowman M, Banach M, et al. The use of DSM-IV and ICD-10 criteria and diagnostic scales for delirium among cardiac surgery patients: results from the IPDACS study. J Neuropsychiatr Clin Neurosci. 2010;22:426–32.CrossRef
5.
go back to reference Dubljanin-Raspopovic E, Markovic Denic L, Marinkovic J, et al. Use of early indicators in rehabilitation process to predict one-year mortality in elderly hip fracture patients. Hip Int. 2012;22:661–7.CrossRefPubMed Dubljanin-Raspopovic E, Markovic Denic L, Marinkovic J, et al. Use of early indicators in rehabilitation process to predict one-year mortality in elderly hip fracture patients. Hip Int. 2012;22:661–7.CrossRefPubMed
6.
go back to reference Bickel H, Gradinger R, Kochs E, et al. High risk of cognitive and functional decline after postoperative delirium. A three-year prospective study. Dement Geriatr Cogn Disord. 2008;26:26–31.CrossRefPubMed Bickel H, Gradinger R, Kochs E, et al. High risk of cognitive and functional decline after postoperative delirium. A three-year prospective study. Dement Geriatr Cogn Disord. 2008;26:26–31.CrossRefPubMed
7.
go back to reference Kat MG, Vreeswijk R, de Jonghe JF, et al. Long-term cognitive outcome of delirium in elderly hip surgery patients. A prospective matched controlled study over two and a half years. Dement Geriatr Cogn Disord. 2008;26:1–8.CrossRefPubMed Kat MG, Vreeswijk R, de Jonghe JF, et al. Long-term cognitive outcome of delirium in elderly hip surgery patients. A prospective matched controlled study over two and a half years. Dement Geriatr Cogn Disord. 2008;26:1–8.CrossRefPubMed
8.
go back to reference Zakriya K, Sieber FE, Christmas C, et al. Brief postoperative delirium in hip fracture patients affects functional outcome at three months. Anesth Analg. 2004;98:1798–802.CrossRefPubMed Zakriya K, Sieber FE, Christmas C, et al. Brief postoperative delirium in hip fracture patients affects functional outcome at three months. Anesth Analg. 2004;98:1798–802.CrossRefPubMed
9.
go back to reference ∙ Saczynski JS, Marcantonio ER, Quach L, et al. Cognitive trajectories after postoperative delirium. N Engl J Med. 2012;367:30–9. The participants who developed postoperative delirium had lower mean baseline MMSE scores than those who did not develop delirium. Those with delirium had a larger drop in MMSE score measured at three time points: 2 days, 1 month, and 1 year after surgery. ∙ Saczynski JS, Marcantonio ER, Quach L, et al. Cognitive trajectories after postoperative delirium. N Engl J Med. 2012;367:30–9. The participants who developed postoperative delirium had lower mean baseline MMSE scores than those who did not develop delirium. Those with delirium had a larger drop in MMSE score measured at three time points: 2 days, 1 month, and 1 year after surgery.
10.
go back to reference American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders. 5th ed. Arlington: American Psychiatric Association; 2013.CrossRef American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders. 5th ed. Arlington: American Psychiatric Association; 2013.CrossRef
11.
go back to reference Inouye SK, Charpentier PA. Precipitating factors for delirium in hospitalized elderly persons. Predictive model and interrelationship with baseline vulnerability. JAMA. 1996;275:852–7.CrossRefPubMed Inouye SK, Charpentier PA. Precipitating factors for delirium in hospitalized elderly persons. Predictive model and interrelationship with baseline vulnerability. JAMA. 1996;275:852–7.CrossRefPubMed
12.
go back to reference Fox HM, Rizzo ND, Gifford S. Psychological observations of patients undergoing mitral surgery; a study of stress. Am Heart J. 1954;5:645–70.CrossRef Fox HM, Rizzo ND, Gifford S. Psychological observations of patients undergoing mitral surgery; a study of stress. Am Heart J. 1954;5:645–70.CrossRef
13.
go back to reference Katznelson R, Djaiani GN, Borger MA, et al. Preoperative use of statins is associated with reduced early delirium rates after cardiac surgery. Anesthesiology. 2009;110:67–73.CrossRefPubMed Katznelson R, Djaiani GN, Borger MA, et al. Preoperative use of statins is associated with reduced early delirium rates after cardiac surgery. Anesthesiology. 2009;110:67–73.CrossRefPubMed
14.
go back to reference Krzych LJ, Wybraniec MT, Krupka-Matuszczyk I, et al. Complex assessment of the incidence and risk factors of delirium in a large cohort of cardiac surgery patients: a single-center 6-year experience. Biomed Res Int. 2013;2013:835850.CrossRefPubMedPubMedCentral Krzych LJ, Wybraniec MT, Krupka-Matuszczyk I, et al. Complex assessment of the incidence and risk factors of delirium in a large cohort of cardiac surgery patients: a single-center 6-year experience. Biomed Res Int. 2013;2013:835850.CrossRefPubMedPubMedCentral
15.
go back to reference Bucerius J, Gummert JF, Borger MA, et al. Predictors of delirium after cardiac surgery delirium: effect of beating-heart (off-pump) surgery. J Thorac Cardiovasc Surg. 2004;127:57–64.CrossRefPubMed Bucerius J, Gummert JF, Borger MA, et al. Predictors of delirium after cardiac surgery delirium: effect of beating-heart (off-pump) surgery. J Thorac Cardiovasc Surg. 2004;127:57–64.CrossRefPubMed
16.
go back to reference Kazmierski J, Kowman M, Banach M, et al. Incidence and predictors of delirium after cardiac surgery: results from The IPDACS Study. J Psychosom Res. 2010;69:179–85.CrossRefPubMed Kazmierski J, Kowman M, Banach M, et al. Incidence and predictors of delirium after cardiac surgery: results from The IPDACS Study. J Psychosom Res. 2010;69:179–85.CrossRefPubMed
17.
go back to reference Smulter N, Lingehall HC, Gustafson Y, et al. Delirium after cardiac surgery: incidence and risk factors. Interact CardioVasc Thorac Surg. 2013;17:790–6.CrossRefPubMedPubMedCentral Smulter N, Lingehall HC, Gustafson Y, et al. Delirium after cardiac surgery: incidence and risk factors. Interact CardioVasc Thorac Surg. 2013;17:790–6.CrossRefPubMedPubMedCentral
18.
go back to reference Loponen P, Luther M, Wistbacka JO, et al. Postoperative delirium and health related quality of life after coronary artery bypass grafting. Scand Cardiovasc J. 2008;42:337–44.CrossRefPubMed Loponen P, Luther M, Wistbacka JO, et al. Postoperative delirium and health related quality of life after coronary artery bypass grafting. Scand Cardiovasc J. 2008;42:337–44.CrossRefPubMed
19.
go back to reference Rudolph JL, Jones RN, Levkoff SE, et al. Derivation and validation of a preoperative prediction rule for delirium after cardiac surgery. Circulation. 2009;119:229–36.CrossRefPubMed Rudolph JL, Jones RN, Levkoff SE, et al. Derivation and validation of a preoperative prediction rule for delirium after cardiac surgery. Circulation. 2009;119:229–36.CrossRefPubMed
20.
go back to reference Rudolph JL, Babikian VL, Birjiniuk V, et al. Atherosclerosis is associated with delirium after coronary artery bypass graft surgery. J Am Geriatr Soc. 2005;53:462–6.CrossRefPubMed Rudolph JL, Babikian VL, Birjiniuk V, et al. Atherosclerosis is associated with delirium after coronary artery bypass graft surgery. J Am Geriatr Soc. 2005;53:462–6.CrossRefPubMed
21.
go back to reference Otomo S, Maekawa K, Goto T, et al. Pre-existing cerebral infarcts as a risk factor for delirium after coronary artery bypass graft surgery. Interact CardioVasc Thorac Surg. 2013;17:799–804.CrossRefPubMedPubMedCentral Otomo S, Maekawa K, Goto T, et al. Pre-existing cerebral infarcts as a risk factor for delirium after coronary artery bypass graft surgery. Interact CardioVasc Thorac Surg. 2013;17:799–804.CrossRefPubMedPubMedCentral
22.
go back to reference Miyazaki S, Yoshitani K, Miura N, et al. Risk factors of stroke and delirium after off-pump coronary artery bypass surgery. Interact CardioVasc Thorac Surg. 2011;12:379–83.CrossRefPubMed Miyazaki S, Yoshitani K, Miura N, et al. Risk factors of stroke and delirium after off-pump coronary artery bypass surgery. Interact CardioVasc Thorac Surg. 2011;12:379–83.CrossRefPubMed
23.
go back to reference Stransky M, Schmidt C, Ganslmeier P, et al. Hypoactive delirium after cardiac surgery as an independent risk factor for prolonged mechanical ventilation. J Cardiothorac Vasc Anesth. 2011;25:968–74.CrossRefPubMed Stransky M, Schmidt C, Ganslmeier P, et al. Hypoactive delirium after cardiac surgery as an independent risk factor for prolonged mechanical ventilation. J Cardiothorac Vasc Anesth. 2011;25:968–74.CrossRefPubMed
24.
go back to reference Shioiri A, Kurumaji A, Takeuchi T, et al. White matter abnormalities as a risk factor for postoperative delirium revealed by diffusion tensor imaging. Am J Geriatr Psychiatry. 2010;18:743–53.CrossRefPubMed Shioiri A, Kurumaji A, Takeuchi T, et al. White matter abnormalities as a risk factor for postoperative delirium revealed by diffusion tensor imaging. Am J Geriatr Psychiatry. 2010;18:743–53.CrossRefPubMed
25.
go back to reference Rudolph JL, Jones RN, Grande LJ, et al. Impaired executive function is associated with delirium after coronary artery bypass graft surgery. J Am Geriatr Soc. 2006;54:937–41.CrossRefPubMedPubMedCentral Rudolph JL, Jones RN, Grande LJ, et al. Impaired executive function is associated with delirium after coronary artery bypass graft surgery. J Am Geriatr Soc. 2006;54:937–41.CrossRefPubMedPubMedCentral
26.
go back to reference Guenther U, Theuerkauf N, Frommann I, et al. Predisposing and precipitating factors of delirium after cardiac surgery: a prospective observational cohort study. Ann Surg. 2013;257:1160–7.CrossRefPubMed Guenther U, Theuerkauf N, Frommann I, et al. Predisposing and precipitating factors of delirium after cardiac surgery: a prospective observational cohort study. Ann Surg. 2013;257:1160–7.CrossRefPubMed
27.
go back to reference Veliz-Reissmuller G, Aguero Torres H, van der Linden J, et al. Pre-operative mild cognitive dysfunction predicts risk for post-operative delirium after elective cardiac surgery. Aging Clin Exp Res. 2007;19:172–7.CrossRefPubMed Veliz-Reissmuller G, Aguero Torres H, van der Linden J, et al. Pre-operative mild cognitive dysfunction predicts risk for post-operative delirium after elective cardiac surgery. Aging Clin Exp Res. 2007;19:172–7.CrossRefPubMed
28.
go back to reference Tan MC, Felde A, Kuskowski M, et al. Incidence and predictors of post-cardiotomy delirium. Am J Geriatr Psychiatry. 2008;16:575–83.CrossRefPubMed Tan MC, Felde A, Kuskowski M, et al. Incidence and predictors of post-cardiotomy delirium. Am J Geriatr Psychiatry. 2008;16:575–83.CrossRefPubMed
29.
go back to reference Hudetz JA, Hoffmann RG, Patterson KM, et al. Preoperative dispositional optimism correlates with a reduced incidence of postoperative delirium and recovery of postoperative cognitive function in cardiac surgical patients. J Cardiothorac Vasc Anesth. 2010;24:560–7.CrossRefPubMed Hudetz JA, Hoffmann RG, Patterson KM, et al. Preoperative dispositional optimism correlates with a reduced incidence of postoperative delirium and recovery of postoperative cognitive function in cardiac surgical patients. J Cardiothorac Vasc Anesth. 2010;24:560–7.CrossRefPubMed
30.
go back to reference Schoen J, Meyerrose J, Paarmann H, et al. Preoperative regional cerebral oxygen saturation is a predictor of postoperative delirium in on-pump cardiac surgery patients: a prospective observational trial. Crit Care. 2011;15:R218.CrossRefPubMedPubMedCentral Schoen J, Meyerrose J, Paarmann H, et al. Preoperative regional cerebral oxygen saturation is a predictor of postoperative delirium in on-pump cardiac surgery patients: a prospective observational trial. Crit Care. 2011;15:R218.CrossRefPubMedPubMedCentral
31.
go back to reference Radtke FM, Franck M, MacGuill M, et al. Duration of fluid fasting and choice of analgesic are modifiable factors for early postoperative delirium. Eur J Anaesthesiol. 2010;27:411–6.CrossRefPubMed Radtke FM, Franck M, MacGuill M, et al. Duration of fluid fasting and choice of analgesic are modifiable factors for early postoperative delirium. Eur J Anaesthesiol. 2010;27:411–6.CrossRefPubMed
32.
go back to reference Katznelson R, Djaiani G, Mitsakakis N, et al. Delirium following vascular surgery: increased incidence with preoperative beta-blocker administration. Can J Anaesth. 2009;56:793–801.CrossRefPubMed Katznelson R, Djaiani G, Mitsakakis N, et al. Delirium following vascular surgery: increased incidence with preoperative beta-blocker administration. Can J Anaesth. 2009;56:793–801.CrossRefPubMed
33.
go back to reference Ushida T, Yokoyama T, Kishida Y, et al. Incidence and risk factors of postoperative delirium in cervical spine surgery. Spine (Phila Pa 1976). 2009;34:2500–4.CrossRef Ushida T, Yokoyama T, Kishida Y, et al. Incidence and risk factors of postoperative delirium in cervical spine surgery. Spine (Phila Pa 1976). 2009;34:2500–4.CrossRef
34.
go back to reference Lowery DP, Wesnes K, Ballard CG. Subtle attentional deficits in the absence of dementia are associated with an increased risk of post-operative delirium. Dement Geriatr Cogn Disord. 2007;23:390–4.CrossRefPubMed Lowery DP, Wesnes K, Ballard CG. Subtle attentional deficits in the absence of dementia are associated with an increased risk of post-operative delirium. Dement Geriatr Cogn Disord. 2007;23:390–4.CrossRefPubMed
35.
go back to reference ∙ Jankowski CJ, Trenerry MR, Cook DJ, et al. Cognitive and functional predictors and sequelae of postoperative delirium in elderly patients undergoing elective joint arthroplasty. Anesth Analg. 2011;112:1186–93. Variables that independently predicted postoperative delirium included age, history of psychiatric illness, decreased functional status, and decreased verbal memory. In those who developed postoperative delirium, there was no evidence of adverse cognitive or functional outcomes 3 months postoperatively. ∙ Jankowski CJ, Trenerry MR, Cook DJ, et al. Cognitive and functional predictors and sequelae of postoperative delirium in elderly patients undergoing elective joint arthroplasty. Anesth Analg. 2011;112:1186–93. Variables that independently predicted postoperative delirium included age, history of psychiatric illness, decreased functional status, and decreased verbal memory. In those who developed postoperative delirium, there was no evidence of adverse cognitive or functional outcomes 3 months postoperatively.
36.
go back to reference Greene NH, Attix DK, Weldon BC, et al. Measures of executive function and depression identify patients at risk for postoperative delirium. Anesthesiology. 2009;110:788–95.CrossRefPubMed Greene NH, Attix DK, Weldon BC, et al. Measures of executive function and depression identify patients at risk for postoperative delirium. Anesthesiology. 2009;110:788–95.CrossRefPubMed
37.
go back to reference Leung JM, Sands LP, Mullen EA, et al. Are preoperative depressive symptoms associated with postoperative delirium in geriatric surgical patients? J Gerontol A Biol Sci Med Sci. 2005;60:1563–8.CrossRefPubMed Leung JM, Sands LP, Mullen EA, et al. Are preoperative depressive symptoms associated with postoperative delirium in geriatric surgical patients? J Gerontol A Biol Sci Med Sci. 2005;60:1563–8.CrossRefPubMed
38.
go back to reference Smith PJ, Attix DK, Weldon BC, et al. Executive function and depression as independent risk factors for postoperative delirium. Anesthesiology. 2009;110:781–7.CrossRefPubMed Smith PJ, Attix DK, Weldon BC, et al. Executive function and depression as independent risk factors for postoperative delirium. Anesthesiology. 2009;110:781–7.CrossRefPubMed
39.
go back to reference Benoit AG, Campbell BI, Tanner JR, et al. Risk factors and prevalence of perioperative cognitive dysfunction in abdominal aneurysm patients. J Vasc Surg. 2005;42:884–90.CrossRefPubMed Benoit AG, Campbell BI, Tanner JR, et al. Risk factors and prevalence of perioperative cognitive dysfunction in abdominal aneurysm patients. J Vasc Surg. 2005;42:884–90.CrossRefPubMed
40.
go back to reference Hattori H, Kamiya J, Shimada H, et al. Assessment of the risk of postoperative delirium in elderly patients using E-PASS and the NEECHAM confusion scale. Int J Geriatr Psychiatry. 2009;24:1304–10.CrossRefPubMed Hattori H, Kamiya J, Shimada H, et al. Assessment of the risk of postoperative delirium in elderly patients using E-PASS and the NEECHAM confusion scale. Int J Geriatr Psychiatry. 2009;24:1304–10.CrossRefPubMed
41.
go back to reference Do TD, Lemogne C, Journois D, et al. Low social support is associated with an increased risk of postoperative delirium. J Clin Anesth. 2012;24:126–32.CrossRefPubMed Do TD, Lemogne C, Journois D, et al. Low social support is associated with an increased risk of postoperative delirium. J Clin Anesth. 2012;24:126–32.CrossRefPubMed
42.
go back to reference Shah S, Weed HG, He X, et al. Alcohol-related predictors of delirium after major head and neck cancer surgery. Arch Otolaryngol Head Neck Surg. 2012;138:266–71.CrossRefPubMed Shah S, Weed HG, He X, et al. Alcohol-related predictors of delirium after major head and neck cancer surgery. Arch Otolaryngol Head Neck Surg. 2012;138:266–71.CrossRefPubMed
43.
go back to reference Patti R, Saitta M, Cusumano G, et al. Risk factors for postoperative delirium after colorectal surgery for carcinoma. Eur J Oncol Nurs. 2011;15:519–23.CrossRefPubMed Patti R, Saitta M, Cusumano G, et al. Risk factors for postoperative delirium after colorectal surgery for carcinoma. Eur J Oncol Nurs. 2011;15:519–23.CrossRefPubMed
44.
go back to reference Ganai S, Lee KF, Merrill A, et al. Adverse outcomes of geriatric patients undergoing abdominal surgery who are at high risk for delirium. Arch Surg. 2007;142:1072–8.CrossRefPubMed Ganai S, Lee KF, Merrill A, et al. Adverse outcomes of geriatric patients undergoing abdominal surgery who are at high risk for delirium. Arch Surg. 2007;142:1072–8.CrossRefPubMed
45.
go back to reference Tei M, Ikeda M, Haraguchi N, et al. Risk factors for postoperative delirium in elderly patients with colorectal cancer. Surg Endosc. 2010;24:2135–9.CrossRefPubMed Tei M, Ikeda M, Haraguchi N, et al. Risk factors for postoperative delirium in elderly patients with colorectal cancer. Surg Endosc. 2010;24:2135–9.CrossRefPubMed
46.
go back to reference Juliebo V, Bjoro K, Krogseth M, et al. Risk factors for preoperative and postoperative delirium in elderly patients with hip fracture. J Am Geriatr Soc. 2009;57:1354–61.CrossRefPubMed Juliebo V, Bjoro K, Krogseth M, et al. Risk factors for preoperative and postoperative delirium in elderly patients with hip fracture. J Am Geriatr Soc. 2009;57:1354–61.CrossRefPubMed
47.
go back to reference Tognoni P, Simonato A, Robutti N, et al. Preoperative risk factors for postoperative delirium (POD) after urological surgery in the elderly. Arch Gerontol Geriatr. 2011;52:e166–9.CrossRefPubMed Tognoni P, Simonato A, Robutti N, et al. Preoperative risk factors for postoperative delirium (POD) after urological surgery in the elderly. Arch Gerontol Geriatr. 2011;52:e166–9.CrossRefPubMed
48.
go back to reference Brouquet A, Cudennec T, Benoist S, et al. Impaired mobility, ASA status and administration of tramadol are risk factors for postoperative delirium in patients aged 75 years or more after major abdominal surgery. Ann Surg. 2010;251:759–65.CrossRefPubMed Brouquet A, Cudennec T, Benoist S, et al. Impaired mobility, ASA status and administration of tramadol are risk factors for postoperative delirium in patients aged 75 years or more after major abdominal surgery. Ann Surg. 2010;251:759–65.CrossRefPubMed
49.
go back to reference Leung JM, Sands LP, Wang Y, et al. Apolipoprotein E e4 allele increases the risk of early postoperative delirium in older patients undergoing noncardiac surgery. Anesthesiology. 2007;107:406–11.CrossRefPubMed Leung JM, Sands LP, Wang Y, et al. Apolipoprotein E e4 allele increases the risk of early postoperative delirium in older patients undergoing noncardiac surgery. Anesthesiology. 2007;107:406–11.CrossRefPubMed
50.
go back to reference van Munster BC, Korevaar JC, Zwinderman AH, et al. The association between delirium and the apolipoprotein E epsilon 4 allele: new study results and a meta-analysis. Am J Geriatr Psychiatry. 2009;17:856–62.CrossRefPubMed van Munster BC, Korevaar JC, Zwinderman AH, et al. The association between delirium and the apolipoprotein E epsilon 4 allele: new study results and a meta-analysis. Am J Geriatr Psychiatry. 2009;17:856–62.CrossRefPubMed
51.
go back to reference Bryson GL, Wyand A, Wozny D, et al. A prospective cohort study evaluating associations among delirium, postoperative cognitive dysfunction, and apolipoprotein E genotype following open aortic repair. Can J Anaesth. 2011;58:246–55.CrossRefPubMed Bryson GL, Wyand A, Wozny D, et al. A prospective cohort study evaluating associations among delirium, postoperative cognitive dysfunction, and apolipoprotein E genotype following open aortic repair. Can J Anaesth. 2011;58:246–55.CrossRefPubMed
52.
go back to reference Andrejaitiene J, Sirvinskas E. Early post-cardiac surgery delirium risk factors. Perfusion. 2012;27:105–12.CrossRefPubMed Andrejaitiene J, Sirvinskas E. Early post-cardiac surgery delirium risk factors. Perfusion. 2012;27:105–12.CrossRefPubMed
53.
go back to reference Bakker RC, Osse RJ, Tulen JH, et al. Preoperative and operative predictors of delirium after cardiac surgery in elderly patients. Eur J Cardiothorac Surg. 2012;41:544–9.CrossRefPubMed Bakker RC, Osse RJ, Tulen JH, et al. Preoperative and operative predictors of delirium after cardiac surgery in elderly patients. Eur J Cardiothorac Surg. 2012;41:544–9.CrossRefPubMed
54.
go back to reference Norkiene I, Ringaitiene D, Misiuriene I, et al. Incidence and precipitating factors of delirium after coronary artery bypass grafting. Scand Cardiovasc J. 2007;41:180–5.CrossRefPubMed Norkiene I, Ringaitiene D, Misiuriene I, et al. Incidence and precipitating factors of delirium after coronary artery bypass grafting. Scand Cardiovasc J. 2007;41:180–5.CrossRefPubMed
55.
go back to reference Osse RJ, Fekkes D, Tulen JH, et al. High preoperative plasma neopterin predicts delirium after cardiac surgery in older adults. J Am Geriatr Soc. 2012;60:661–8.CrossRefPubMed Osse RJ, Fekkes D, Tulen JH, et al. High preoperative plasma neopterin predicts delirium after cardiac surgery in older adults. J Am Geriatr Soc. 2012;60:661–8.CrossRefPubMed
56.
go back to reference Hudetz JA, Iqbal Z, Gandhi SD, et al. Postoperative delirium and short-term cognitive dysfunction occur more frequently in patients undergoing valve surgery with or without coronary artery bypass graft surgery compared with coronary artery bypass graft surgery alone: results of a pilot study. J Cardiothorac Vasc Anesth. 2011;25:811–6.CrossRefPubMed Hudetz JA, Iqbal Z, Gandhi SD, et al. Postoperative delirium and short-term cognitive dysfunction occur more frequently in patients undergoing valve surgery with or without coronary artery bypass graft surgery compared with coronary artery bypass graft surgery alone: results of a pilot study. J Cardiothorac Vasc Anesth. 2011;25:811–6.CrossRefPubMed
57.
go back to reference Detroyer E, Dobbels F, Verfaillie E, et al. Is preoperative anxiety and depression associated with onset of delirium after cardiac surgery in older patients? A prospective cohort study. J Am Geriatr Soc. 2008;56:2278–84.CrossRefPubMed Detroyer E, Dobbels F, Verfaillie E, et al. Is preoperative anxiety and depression associated with onset of delirium after cardiac surgery in older patients? A prospective cohort study. J Am Geriatr Soc. 2008;56:2278–84.CrossRefPubMed
58.
go back to reference Siepe M, Pfeiffer T, Gieringer A, et al. Increased systemic perfusion pressure during cardiopulmonary bypass is associated with less early postoperative cognitive dysfunction and delirium. Eur J Cardiothorac Surg. 2011;40:200–7.CrossRefPubMed Siepe M, Pfeiffer T, Gieringer A, et al. Increased systemic perfusion pressure during cardiopulmonary bypass is associated with less early postoperative cognitive dysfunction and delirium. Eur J Cardiothorac Surg. 2011;40:200–7.CrossRefPubMed
59.
go back to reference Murzi M, Cerillo AG, Miceli A, et al. Antegrade and retrograde arterial perfusion strategy in minimally invasive mitral-valve surgery: a propensity score analysis on 1280 patients. Eur J Cardiothorac Surg. 2013;43:e167–72.CrossRefPubMed Murzi M, Cerillo AG, Miceli A, et al. Antegrade and retrograde arterial perfusion strategy in minimally invasive mitral-valve surgery: a propensity score analysis on 1280 patients. Eur J Cardiothorac Surg. 2013;43:e167–72.CrossRefPubMed
60.
go back to reference Norkiene I, Ringaitiene D, Kuzminskaite V, et al. Incidence and risk factors of early delirium after cardiac surgery. Biomed Res Int. 2013;2013:323491.CrossRefPubMedPubMedCentral Norkiene I, Ringaitiene D, Kuzminskaite V, et al. Incidence and risk factors of early delirium after cardiac surgery. Biomed Res Int. 2013;2013:323491.CrossRefPubMedPubMedCentral
61.
62.
go back to reference ∙∙ Whitlock EL, Torres BA, Lin N, et al. Postoperative delirium in a substudy of cardiothoracic surgical patients in the BAG-RECALL clinical trial. Anesth Analg. 2014;118:809–17. There was a nonsignificant trend toward less delirium in the BIS-guided anesthetic group compared to the end-tidal anesthetic concentration-guided group. Low average volatile anesthetic dose, intraoperative transfusion, ASA physical status, and European System for Cardiac Operative Risk Evaluation were independent predictors of delirium. ∙∙ Whitlock EL, Torres BA, Lin N, et al. Postoperative delirium in a substudy of cardiothoracic surgical patients in the BAG-RECALL clinical trial. Anesth Analg. 2014;118:809–17. There was a nonsignificant trend toward less delirium in the BIS-guided anesthetic group compared to the end-tidal anesthetic concentration-guided group. Low average volatile anesthetic dose, intraoperative transfusion, ASA physical status, and European System for Cardiac Operative Risk Evaluation were independent predictors of delirium.
63.
go back to reference Burkhart CS, Dell-Kuster S, Gamberini M, et al. Modifiable and nonmodifiable risk factors for postoperative delirium after cardiac surgery with cardiopulmonary bypass. J Cardiothorac Vasc Anesth. 2010;24:555–9.CrossRefPubMed Burkhart CS, Dell-Kuster S, Gamberini M, et al. Modifiable and nonmodifiable risk factors for postoperative delirium after cardiac surgery with cardiopulmonary bypass. J Cardiothorac Vasc Anesth. 2010;24:555–9.CrossRefPubMed
64.
go back to reference Marcantonio ER, Goldman L, Orav EJ, et al. The association of intraoperative factors with the development of postoperative delirium. Am J Med. 1998;105:380–4.CrossRefPubMed Marcantonio ER, Goldman L, Orav EJ, et al. The association of intraoperative factors with the development of postoperative delirium. Am J Med. 1998;105:380–4.CrossRefPubMed
65.
go back to reference Olin K, Eriksdotter-Jonhagen M, Jansson A, et al. Postoperative delirium in elderly patients after major abdominal surgery. Br J Surg. 2005;92:1559–64.CrossRefPubMed Olin K, Eriksdotter-Jonhagen M, Jansson A, et al. Postoperative delirium in elderly patients after major abdominal surgery. Br J Surg. 2005;92:1559–64.CrossRefPubMed
66.
67.
go back to reference Bohner H, Hummel TC, Habel U, et al. Predicting delirium after vascular surgery: a model based on pre- and intraoperative data. Ann Surg. 2003;238:149–56.PubMedPubMedCentral Bohner H, Hummel TC, Habel U, et al. Predicting delirium after vascular surgery: a model based on pre- and intraoperative data. Ann Surg. 2003;238:149–56.PubMedPubMedCentral
68.
go back to reference Lescot T, Karvellas CJ, Chaudhury P, et al. Postoperative delirium in the intensive care unit predicts worse outcomes in liver transplant recipients. Can J Gastroenterol. 2013;27:207–12.CrossRefPubMedPubMedCentral Lescot T, Karvellas CJ, Chaudhury P, et al. Postoperative delirium in the intensive care unit predicts worse outcomes in liver transplant recipients. Can J Gastroenterol. 2013;27:207–12.CrossRefPubMedPubMedCentral
69.
go back to reference Behrends M, DePalma G, Sands L, et al. Association between intraoperative blood transfusions and early postoperative delirium in older adults. J Am Geriatr Soc. 2013;61:365–70.CrossRefPubMedPubMedCentral Behrends M, DePalma G, Sands L, et al. Association between intraoperative blood transfusions and early postoperative delirium in older adults. J Am Geriatr Soc. 2013;61:365–70.CrossRefPubMedPubMedCentral
70.
go back to reference Kalisvaart KJ, Vreeswijk R, de Jonghe JF, et al. Risk factors and prediction of postoperative delirium in elderly hip-surgery patients: implementation and validation of a medical risk factor model. J Am Geriatr Soc. 2006;54:817–22.CrossRefPubMed Kalisvaart KJ, Vreeswijk R, de Jonghe JF, et al. Risk factors and prediction of postoperative delirium in elderly hip-surgery patients: implementation and validation of a medical risk factor model. J Am Geriatr Soc. 2006;54:817–22.CrossRefPubMed
71.
go back to reference Koebrugge B, van Wensen RJ, Bosscha K, et al. Delirium after emergency/elective open and endovascular aortoiliac surgery at a surgical ward with a high-standard delirium care protocol. Vascular. 2010;18:279–87.CrossRefPubMed Koebrugge B, van Wensen RJ, Bosscha K, et al. Delirium after emergency/elective open and endovascular aortoiliac surgery at a surgical ward with a high-standard delirium care protocol. Vascular. 2010;18:279–87.CrossRefPubMed
72.
go back to reference Salata K, Katznelson R, Beattie WS, et al. Endovascular versus open approach to aortic aneurysm repair surgery: rates of postoperative delirium. Can J Anaesth. 2012;59:556–61.CrossRefPubMed Salata K, Katznelson R, Beattie WS, et al. Endovascular versus open approach to aortic aneurysm repair surgery: rates of postoperative delirium. Can J Anaesth. 2012;59:556–61.CrossRefPubMed
73.
go back to reference Mason SE, Noel-Storr A, Ritchie CW. The impact of general and regional anesthesia on the incidence of post-operative cognitive dysfunction and post-operative delirium: a systematic review with meta-analysis. J Alzheimers Dis. 2010;22(Suppl 3):67–79.CrossRefPubMed Mason SE, Noel-Storr A, Ritchie CW. The impact of general and regional anesthesia on the incidence of post-operative cognitive dysfunction and post-operative delirium: a systematic review with meta-analysis. J Alzheimers Dis. 2010;22(Suppl 3):67–79.CrossRefPubMed
74.
go back to reference Ellard L, Katznelson R, Wasowicz M, et al. Type of anesthesia and postoperative delirium after vascular surgery. J Cardiothorac Vasc Anesth. 2014;28:458–61.CrossRefPubMed Ellard L, Katznelson R, Wasowicz M, et al. Type of anesthesia and postoperative delirium after vascular surgery. J Cardiothorac Vasc Anesth. 2014;28:458–61.CrossRefPubMed
75.
go back to reference Slor CJ, de Jonghe JF, Vreeswijk R, et al. Anesthesia and postoperative delirium in older adults undergoing hip surgery. J Am Geriatr Soc. 2011;59:1313–9.CrossRefPubMed Slor CJ, de Jonghe JF, Vreeswijk R, et al. Anesthesia and postoperative delirium in older adults undergoing hip surgery. J Am Geriatr Soc. 2011;59:1313–9.CrossRefPubMed
76.
go back to reference ∙∙ Sieber FE, Zakriya KJ, Gottschalk A, et al. Sedation depth during spinal anesthesia and the development of postoperative delirium in elderly patients undergoing hip fracture repair. Mayo Clin Proc. 2010;85:18–26. During spinal anesthesia, light propofol sedation decreased the prevalence of delirium by 50% compared with deep sedation. ∙∙ Sieber FE, Zakriya KJ, Gottschalk A, et al. Sedation depth during spinal anesthesia and the development of postoperative delirium in elderly patients undergoing hip fracture repair. Mayo Clin Proc. 2010;85:18–26. During spinal anesthesia, light propofol sedation decreased the prevalence of delirium by 50% compared with deep sedation.
77.
go back to reference ∙ Chan MT, Cheng BC, Lee TM, et al. BIS-guided anesthesia decreases postoperative delirium and cognitive decline. J Neurosurg Anesthesiol. 2013;25:33–42. When compared to routine care, BIS-guided anesthesia decreased the incidence of postoperative delirium and the incidence of postoperative cognitive dysfunction 3 months postoperatively. ∙ Chan MT, Cheng BC, Lee TM, et al. BIS-guided anesthesia decreases postoperative delirium and cognitive decline. J Neurosurg Anesthesiol. 2013;25:33–42. When compared to routine care, BIS-guided anesthesia decreased the incidence of postoperative delirium and the incidence of postoperative cognitive dysfunction 3 months postoperatively.
78.
go back to reference ∙ Radtke FM, Franck M, Lendner J, et al. Monitoring depth of anaesthesia in a randomized trial decreases the rate of postoperative delirium but not postoperative cognitive dysfunction. Br J Anaesth. 2013;110 Suppl 1:i98–105. The use of BIS-guided anesthesia decreased the incidence of postoperative delirium but did not change the incidence of postoperative cognitive dysfunction in a cohort of elderly patients undergoing elective surgery. ∙ Radtke FM, Franck M, Lendner J, et al. Monitoring depth of anaesthesia in a randomized trial decreases the rate of postoperative delirium but not postoperative cognitive dysfunction. Br J Anaesth. 2013;110 Suppl 1:i98–105. The use of BIS-guided anesthesia decreased the incidence of postoperative delirium but did not change the incidence of postoperative cognitive dysfunction in a cohort of elderly patients undergoing elective surgery.
79.
go back to reference LuratiBuse GA, Schumacher P, Seeberger E, et al. Randomized comparison of sevoflurane versus propofol to reduce perioperative myocardial ischemia in patients undergoing noncardiac surgery. Circulation. 2012;126:2696–704.CrossRef LuratiBuse GA, Schumacher P, Seeberger E, et al. Randomized comparison of sevoflurane versus propofol to reduce perioperative myocardial ischemia in patients undergoing noncardiac surgery. Circulation. 2012;126:2696–704.CrossRef
80.
go back to reference Vaurio LE, Sands LP, Wang Y, et al. Postoperative delirium: the importance of pain and pain management. Anesth Analg. 2006;102:1267–73.CrossRefPubMed Vaurio LE, Sands LP, Wang Y, et al. Postoperative delirium: the importance of pain and pain management. Anesth Analg. 2006;102:1267–73.CrossRefPubMed
81.
go back to reference Nie H, Zhao B, Zhang YQ, et al. Pain and cognitive dysfunction are the risk factors of delirium in elderly hip fracture Chinese patients. Arch Gerontol Geriatr. 2012;54:e172–4.CrossRefPubMed Nie H, Zhao B, Zhang YQ, et al. Pain and cognitive dysfunction are the risk factors of delirium in elderly hip fracture Chinese patients. Arch Gerontol Geriatr. 2012;54:e172–4.CrossRefPubMed
82.
go back to reference Liu P, Li YW, Wang XS, et al. High serum interleukin-6 level is associated with increased risk of delirium in elderly patients after noncardiac surgery: a prospective cohort study. Chin Med J (Engl). 2013;126:3621–7. Liu P, Li YW, Wang XS, et al. High serum interleukin-6 level is associated with increased risk of delirium in elderly patients after noncardiac surgery: a prospective cohort study. Chin Med J (Engl). 2013;126:3621–7.
83.
go back to reference Contin AM, Perez-Jara J, Alonso-Contin A, et al. Postoperative delirium after elective orthopedic surgery. Int J Geriatr Psychiatry. 2005;20:595–7.CrossRefPubMed Contin AM, Perez-Jara J, Alonso-Contin A, et al. Postoperative delirium after elective orthopedic surgery. Int J Geriatr Psychiatry. 2005;20:595–7.CrossRefPubMed
84.
go back to reference Marino J, Russo J, Kenny M, et al. Continuous lumbar plexus block for postoperative pain control after total hip arthroplasty. A randomized controlled trial. J Bone Joint Surg Am. 2009;91:29–37.CrossRefPubMed Marino J, Russo J, Kenny M, et al. Continuous lumbar plexus block for postoperative pain control after total hip arthroplasty. A randomized controlled trial. J Bone Joint Surg Am. 2009;91:29–37.CrossRefPubMed
85.
go back to reference Kinjo S, Lim E, Sands LP, et al. Does using a femoral nerve block for total knee replacement decrease postoperative delirium? BMC Anesthesiol. 2012;12:4.CrossRefPubMedPubMedCentral Kinjo S, Lim E, Sands LP, et al. Does using a femoral nerve block for total knee replacement decrease postoperative delirium? BMC Anesthesiol. 2012;12:4.CrossRefPubMedPubMedCentral
86.
go back to reference Mouzopoulos G, Vasiliadis G, Lasanianos N, et al. Fascia iliaca block prophylaxis for hip fracture patients at risk for delirium: a randomized placebo-controlled study. J Orthop Traumatol. 2009;10:127–33.CrossRefPubMedPubMedCentral Mouzopoulos G, Vasiliadis G, Lasanianos N, et al. Fascia iliaca block prophylaxis for hip fracture patients at risk for delirium: a randomized placebo-controlled study. J Orthop Traumatol. 2009;10:127–33.CrossRefPubMedPubMedCentral
87.
go back to reference Leung JM, Sands LP, Vaurio LE, et al. Nitrous oxide does not change the incidence of postoperative delirium or cognitive decline in elderly surgical patients. Br J Anaesth. 2006;96:754–60.CrossRefPubMed Leung JM, Sands LP, Vaurio LE, et al. Nitrous oxide does not change the incidence of postoperative delirium or cognitive decline in elderly surgical patients. Br J Anaesth. 2006;96:754–60.CrossRefPubMed
88.
go back to reference Shiiba M, Takei M, Nakatsuru M, et al. Clinical observations of postoperative delirium after surgery for oral carcinoma. Int J Oral Maxillofac Surg. 2009;38:661–5.CrossRefPubMed Shiiba M, Takei M, Nakatsuru M, et al. Clinical observations of postoperative delirium after surgery for oral carcinoma. Int J Oral Maxillofac Surg. 2009;38:661–5.CrossRefPubMed
89.
go back to reference McAlpine JN, Hodgson EJ, Abramowitz S, et al. The incidence and risk factors associated with postoperative delirium in geriatric patients undergoing surgery for suspected gynecologic malignancies. Gynecol Oncol. 2008;109:296–302.CrossRefPubMed McAlpine JN, Hodgson EJ, Abramowitz S, et al. The incidence and risk factors associated with postoperative delirium in geriatric patients undergoing surgery for suspected gynecologic malignancies. Gynecol Oncol. 2008;109:296–302.CrossRefPubMed
90.
go back to reference Marcantonio ER, Juarez G, Goldman L, et al. The relationship of postoperative delirium with psychoactive medications. JAMA. 1994;272:1518–22.CrossRefPubMed Marcantonio ER, Juarez G, Goldman L, et al. The relationship of postoperative delirium with psychoactive medications. JAMA. 1994;272:1518–22.CrossRefPubMed
91.
go back to reference Morrison RS, Magaziner J, Gilbert M, et al. Relationship between pain and opioid analgesics on the development of delirium following hip fracture. J Gerontol A Biol Sci Med Sci. 2003;58:76–81.CrossRefPubMed Morrison RS, Magaziner J, Gilbert M, et al. Relationship between pain and opioid analgesics on the development of delirium following hip fracture. J Gerontol A Biol Sci Med Sci. 2003;58:76–81.CrossRefPubMed
92.
go back to reference Adunsky A, Levy R, Heim M, et al. Meperidine analgesia and delirium in aged hip fracture patients. Arch Gerontol Geriatr. 2002;35:253–9.CrossRefPubMed Adunsky A, Levy R, Heim M, et al. Meperidine analgesia and delirium in aged hip fracture patients. Arch Gerontol Geriatr. 2002;35:253–9.CrossRefPubMed
93.
go back to reference Yildizeli B, Ozyurtkan MO, Batirel HF, et al. Factors associated with postoperative delirium after thoracic surgery. Ann Thorac Surg. 2005;79:1004–9.CrossRefPubMed Yildizeli B, Ozyurtkan MO, Batirel HF, et al. Factors associated with postoperative delirium after thoracic surgery. Ann Thorac Surg. 2005;79:1004–9.CrossRefPubMed
94.
go back to reference Takeuchi M, Takeuchi H, Fujisawa D, et al. Incidence and risk factors of postoperative delirium in patients with esophageal cancer. Ann Surg Oncol. 2012;19:3963–70.CrossRefPubMed Takeuchi M, Takeuchi H, Fujisawa D, et al. Incidence and risk factors of postoperative delirium in patients with esophageal cancer. Ann Surg Oncol. 2012;19:3963–70.CrossRefPubMed
95.
go back to reference Lin YY, He B, Chen J, et al. Can dexmedetomidine be a safe and efficacious sedative agent in post-cardiac surgery patients? A meta-analysis. Crit Care. 2012;16:R169.CrossRefPubMedPubMedCentral Lin YY, He B, Chen J, et al. Can dexmedetomidine be a safe and efficacious sedative agent in post-cardiac surgery patients? A meta-analysis. Crit Care. 2012;16:R169.CrossRefPubMedPubMedCentral
96.
go back to reference Maldonado JR, Wysong A, van der Starre PJ, et al. Dexmedetomidine and the reduction of postoperative delirium after cardiac surgery. Psychosomatics. 2009;50:206–17.CrossRefPubMed Maldonado JR, Wysong A, van der Starre PJ, et al. Dexmedetomidine and the reduction of postoperative delirium after cardiac surgery. Psychosomatics. 2009;50:206–17.CrossRefPubMed
97.
go back to reference Deiner S, Lin H, Bodansky D, et al. Do stress markers and anesthetic technique predict delirium in the elderly. Dement Geriatr Cogn Disord. 2014;38:366–74.CrossRefPubMed Deiner S, Lin H, Bodansky D, et al. Do stress markers and anesthetic technique predict delirium in the elderly. Dement Geriatr Cogn Disord. 2014;38:366–74.CrossRefPubMed
98.
go back to reference Wang SG, Lee UJ, Goh EK, et al. Factors associated with postoperative delirium after major head and neck surgery. Ann Otol Rhinol Laryngol. 2004;113:48–51.CrossRefPubMed Wang SG, Lee UJ, Goh EK, et al. Factors associated with postoperative delirium after major head and neck surgery. Ann Otol Rhinol Laryngol. 2004;113:48–51.CrossRefPubMed
99.
go back to reference Morimoto Y, Yoshimura M, Utada K, et al. Prediction of postoperative delirium after abdominal surgery in the elderly. J Anesth. 2009;23:51–6.CrossRefPubMed Morimoto Y, Yoshimura M, Utada K, et al. Prediction of postoperative delirium after abdominal surgery in the elderly. J Anesth. 2009;23:51–6.CrossRefPubMed
100.
go back to reference Mangnall LT, Gallagher R, Stein-Parbury J. Postoperative delirium after colorectal surgery in older patients. Am J Crit Care. 2011;20:45–55.CrossRefPubMed Mangnall LT, Gallagher R, Stein-Parbury J. Postoperative delirium after colorectal surgery in older patients. Am J Crit Care. 2011;20:45–55.CrossRefPubMed
101.
102.
go back to reference Pol RA, van Leeuwen BL, Visser L, et al. Standardised frailty indicator as predictor for postoperative delirium after vascular surgery: a prospective cohort study. Eur J Vasc Endovasc Surg. 2011;42:824–30.CrossRefPubMed Pol RA, van Leeuwen BL, Visser L, et al. Standardised frailty indicator as predictor for postoperative delirium after vascular surgery: a prospective cohort study. Eur J Vasc Endovasc Surg. 2011;42:824–30.CrossRefPubMed
103.
go back to reference Sasajima Y, Sasajima T, Azuma N, et al. Factors related to postoperative delirium in patients with lower limb ischaemia: a prospective cohort study. Eur J Vasc Endovasc Surg. 2012;44:411–5.CrossRefPubMed Sasajima Y, Sasajima T, Azuma N, et al. Factors related to postoperative delirium in patients with lower limb ischaemia: a prospective cohort study. Eur J Vasc Endovasc Surg. 2012;44:411–5.CrossRefPubMed
104.
go back to reference Flink BJ, Rivelli SK, Cox EA, et al. Obstructive sleep apnea and incidence of postoperative delirium after elective knee replacement in the nondemented elderly. Anesthesiology. 2012;116:788–96.CrossRefPubMed Flink BJ, Rivelli SK, Cox EA, et al. Obstructive sleep apnea and incidence of postoperative delirium after elective knee replacement in the nondemented elderly. Anesthesiology. 2012;116:788–96.CrossRefPubMed
105.
go back to reference Lee HB, Mears SC, Rosenberg PB, et al. Predisposing factors for postoperative delirium after hip fracture repair in individuals with and without dementia. J Am Geriatr Soc. 2011;59:2306–13.CrossRefPubMedPubMedCentral Lee HB, Mears SC, Rosenberg PB, et al. Predisposing factors for postoperative delirium after hip fracture repair in individuals with and without dementia. J Am Geriatr Soc. 2011;59:2306–13.CrossRefPubMedPubMedCentral
106.
go back to reference Meziere A, Paillaud E, Belmin J, et al. Delirium in older people after proximal femoral fracture repair: role of a preoperative screening cognitive test. Ann Fr Anesth Reanim. 2013;32:e91–6.CrossRefPubMed Meziere A, Paillaud E, Belmin J, et al. Delirium in older people after proximal femoral fracture repair: role of a preoperative screening cognitive test. Ann Fr Anesth Reanim. 2013;32:e91–6.CrossRefPubMed
107.
go back to reference Fineberg SJ, Nandyala SV, Marquez-Lara A, et al. Incidence and risk factors for postoperative delirium after lumbar spine surgery. Spine. 2013;38:1790–6.CrossRefPubMed Fineberg SJ, Nandyala SV, Marquez-Lara A, et al. Incidence and risk factors for postoperative delirium after lumbar spine surgery. Spine. 2013;38:1790–6.CrossRefPubMed
108.
go back to reference Harasawa N, Mizuno T. A novel scale predicting postoperative delirium (POD) in patients undergoing cerebrovascular surgery. Arch Gerontol Geriatr. 2014;59:264–71.CrossRefPubMed Harasawa N, Mizuno T. A novel scale predicting postoperative delirium (POD) in patients undergoing cerebrovascular surgery. Arch Gerontol Geriatr. 2014;59:264–71.CrossRefPubMed
109.
go back to reference Marcantonio ER, Goldman L, Mangione CM, et al. A clinical prediction rule for delirium after elective noncardiac surgery. JAMA. 1994;271:134–9.CrossRefPubMed Marcantonio ER, Goldman L, Mangione CM, et al. A clinical prediction rule for delirium after elective noncardiac surgery. JAMA. 1994;271:134–9.CrossRefPubMed
110.
go back to reference Priner M, Jourdain M, Bouche G, et al. Usefulness of the short IQCODE for predicting postoperative delirium in elderly patients undergoing hip and knee replacement surgery. Gerontology. 2008;54:116–9.CrossRefPubMed Priner M, Jourdain M, Bouche G, et al. Usefulness of the short IQCODE for predicting postoperative delirium in elderly patients undergoing hip and knee replacement surgery. Gerontology. 2008;54:116–9.CrossRefPubMed
111.
go back to reference Krzych LJ, Wybraniec MT, Krupka-Matuszczyk I, et al. Delirium screening in cardiac surgery (DESCARD): a useful tool for nonpsychiatrists. Can J Cardiol. 2014;30:932–9.CrossRefPubMed Krzych LJ, Wybraniec MT, Krupka-Matuszczyk I, et al. Delirium screening in cardiac surgery (DESCARD): a useful tool for nonpsychiatrists. Can J Cardiol. 2014;30:932–9.CrossRefPubMed
112.
go back to reference Freter SH, Dunbar MJ, MacLeod H, et al. Predicting post-operative delirium in elective orthopaedic patients: the delirium elderly at-risk (DEAR) instrument. Age Ageing. 2005;34:169–71.CrossRefPubMed Freter SH, Dunbar MJ, MacLeod H, et al. Predicting post-operative delirium in elective orthopaedic patients: the delirium elderly at-risk (DEAR) instrument. Age Ageing. 2005;34:169–71.CrossRefPubMed
113.
go back to reference Koster S, Hensens AG, Schuurmans MJ, et al. Prediction of delirium after cardiac surgery and the use of a risk checklist. Eur J Cardiovasc Nurs. 2013;12:284–92.CrossRefPubMed Koster S, Hensens AG, Schuurmans MJ, et al. Prediction of delirium after cardiac surgery and the use of a risk checklist. Eur J Cardiovasc Nurs. 2013;12:284–92.CrossRefPubMed
114.
go back to reference Fisher BW, Flowerdew G. A simple model for predicting postoperative delirium in older patients undergoing elective orthopedic surgery. J Am Geriatr Soc. 1995;43:175–8.CrossRefPubMed Fisher BW, Flowerdew G. A simple model for predicting postoperative delirium in older patients undergoing elective orthopedic surgery. J Am Geriatr Soc. 1995;43:175–8.CrossRefPubMed
115.
go back to reference Goldenberg G, Kiselev P, Bharathan T, et al. Predicting post-operative delirium in elderly patients undergoing surgery for hip fracture. Psychogeriatrics. 2006;6:43–8.CrossRef Goldenberg G, Kiselev P, Bharathan T, et al. Predicting post-operative delirium in elderly patients undergoing surgery for hip fracture. Psychogeriatrics. 2006;6:43–8.CrossRef
Metadata
Title
Postoperative Delirium: A Review of Risk Factors and Tools of Prediction
Authors
Katie J. Schenning
Stacie G. Deiner
Publication date
01-03-2015
Publisher
Springer US
Published in
Current Anesthesiology Reports / Issue 1/2015
Electronic ISSN: 2167-6275
DOI
https://doi.org/10.1007/s40140-014-0086-1

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