Skip to main content
Top
Published in: Pain and Therapy 1/2016

Open Access 01-06-2016 | Commentary

Should the General Practitioner Consider Mesotherapy (Intradermal Therapy) to Manage Localized Pain?

Published in: Pain and Therapy | Issue 1/2016

Login to get access

Abstract

Wide variations in the types of pain and response to analgesic pharmacotherapy mean that a variety of treatment strategies are needed. One approach is mesotherapy (intradermal therapy). This consists of microinjections into the skin and is ideally suited to the management of localized pain. Advantages include increasing the duration of drug activity, reduced risk of adverse events and interactions, and possible synergy with other therapies. Mesotherapy provides general practitioners with another tool for the treatment of local pain. However, it is important to provide patients with full details of the pros and cons of this approach and obtain informed patient consent.
Literature
1.
2.
3.
go back to reference Mammucari M, Gatti A, Maggiori S, Bartoletti CA, Sabato AF. Mesotherapy, definition, rationale and clinical role: a consensus report from the Italian Society of Mesotherapy. Eur Rev Med Pharmacol Sci. 2011;15:682–94.PubMed Mammucari M, Gatti A, Maggiori S, Bartoletti CA, Sabato AF. Mesotherapy, definition, rationale and clinical role: a consensus report from the Italian Society of Mesotherapy. Eur Rev Med Pharmacol Sci. 2011;15:682–94.PubMed
4.
go back to reference Mammucari M, Gatti A, Maggiori S, Sabato AF. Role of mesotherapy in musculoskeletal pain: opinions from the Italian Society of Mesotherapy. Evid Based Complement Altern Med. 2012;2012:436959.CrossRef Mammucari M, Gatti A, Maggiori S, Sabato AF. Role of mesotherapy in musculoskeletal pain: opinions from the Italian Society of Mesotherapy. Evid Based Complement Altern Med. 2012;2012:436959.CrossRef
5.
go back to reference Kenney RT, Frech SA, Muenz LR, et al. Dose sparing with intradermal injection of influenza vaccine. N Engl J Med. 2004;351:2295–301.CrossRefPubMed Kenney RT, Frech SA, Muenz LR, et al. Dose sparing with intradermal injection of influenza vaccine. N Engl J Med. 2004;351:2295–301.CrossRefPubMed
6.
go back to reference Mammucari M, Lazzari M, Maggiori E, et al. Role of the informed consent, from mesotherapy to opioid therapy. Eur Rev Med Pharmacol Sci. 2014;18:566–74.PubMed Mammucari M, Lazzari M, Maggiori E, et al. Role of the informed consent, from mesotherapy to opioid therapy. Eur Rev Med Pharmacol Sci. 2014;18:566–74.PubMed
7.
go back to reference Carbonne A, Brossier F, Arnaud I, et al. Outbreak of non-tuberculous mycobacterial subcutaneous infections related to multiple mesotherapy injections. J Clin Microbiol. 2009;47:1961–4.CrossRefPubMedPubMedCentral Carbonne A, Brossier F, Arnaud I, et al. Outbreak of non-tuberculous mycobacterial subcutaneous infections related to multiple mesotherapy injections. J Clin Microbiol. 2009;47:1961–4.CrossRefPubMedPubMedCentral
8.
go back to reference Atiyeh BS, Ibrahim AE, Dibo SA. Cosmetic mesotherapy: between scientific evidence, science fiction, and lucrative business. Aesthet Plast Surg. 2008;32:842–9.CrossRef Atiyeh BS, Ibrahim AE, Dibo SA. Cosmetic mesotherapy: between scientific evidence, science fiction, and lucrative business. Aesthet Plast Surg. 2008;32:842–9.CrossRef
9.
go back to reference Mammucari M, Vellucci R, Mediati RD, et al. What is mesotherapy? Recommendations from an international consensus. Trends Med. 2014;14:1–10. Mammucari M, Vellucci R, Mediati RD, et al. What is mesotherapy? Recommendations from an international consensus. Trends Med. 2014;14:1–10.
10.
go back to reference Parrini M, Bergamaschi R, Azzoni R. Controlled study of acetylsalicylic acid efficacy by mesotherapy in lumbo-sciatic pain. Minerva Ortop e Traumatol. 2002;53(3):181–6. Parrini M, Bergamaschi R, Azzoni R. Controlled study of acetylsalicylic acid efficacy by mesotherapy in lumbo-sciatic pain. Minerva Ortop e Traumatol. 2002;53(3):181–6.
11.
go back to reference Monticone M, Barbarino A, Testi C, Arzano S, Moschi A, Negrini S. Symptomatic efficacy of stabilizing treatment versus laser therapy for sub-acute low back pain with positive tests for sacroiliac dysfunction: a randomised clinical controlled trial with 1 year follow-up. Eura Medicophys. 2004;40(4):263–8.PubMed Monticone M, Barbarino A, Testi C, Arzano S, Moschi A, Negrini S. Symptomatic efficacy of stabilizing treatment versus laser therapy for sub-acute low back pain with positive tests for sacroiliac dysfunction: a randomised clinical controlled trial with 1 year follow-up. Eura Medicophys. 2004;40(4):263–8.PubMed
12.
go back to reference Costantino C, Marangio E, Coruzzi G. Mesotherapy versus systemic therapy in the treatment of acute low back pain: a randomized trial. Evid Based Complement Altern Med. 2011;2011:317183. Costantino C, Marangio E, Coruzzi G. Mesotherapy versus systemic therapy in the treatment of acute low back pain: a randomized trial. Evid Based Complement Altern Med. 2011;2011:317183.
13.
go back to reference Di Cesare A, Giombini A, Di Cesare M, Ripani M, Yulpiani M, Saraceni VM. Comparison between the effects of trigger point mesotherapy versus acupuncture points mesotherapy in the treatment of chronic low back pain: a short term randomized controlled trial. Complement Ther Med. 2011;19(1):19–26.CrossRefPubMed Di Cesare A, Giombini A, Di Cesare M, Ripani M, Yulpiani M, Saraceni VM. Comparison between the effects of trigger point mesotherapy versus acupuncture points mesotherapy in the treatment of chronic low back pain: a short term randomized controlled trial. Complement Ther Med. 2011;19(1):19–26.CrossRefPubMed
14.
go back to reference Cacchio A, De Blasis E, Desiati P, Spacca G, Santilli V, De Paulis F. Effectiveness of treatment of calcific tendinitis of the shoulder by disodium EDTA. Arthritis Rheum. 2009;61(1):84–91.CrossRefPubMed Cacchio A, De Blasis E, Desiati P, Spacca G, Santilli V, De Paulis F. Effectiveness of treatment of calcific tendinitis of the shoulder by disodium EDTA. Arthritis Rheum. 2009;61(1):84–91.CrossRefPubMed
15.
go back to reference Dowell D, Haegerich TM, Chou R. CDC guideline for prescribing opioids for chronic pain—United States, 2016. JAMA. 2016;315(15):1624–45.CrossRefPubMed Dowell D, Haegerich TM, Chou R. CDC guideline for prescribing opioids for chronic pain—United States, 2016. JAMA. 2016;315(15):1624–45.CrossRefPubMed
Metadata
Title
Should the General Practitioner Consider Mesotherapy (Intradermal Therapy) to Manage Localized Pain?
Publication date
01-06-2016
Published in
Pain and Therapy / Issue 1/2016
Print ISSN: 2193-8237
Electronic ISSN: 2193-651X
DOI
https://doi.org/10.1007/s40122-016-0052-3

Other articles of this Issue 1/2016

Pain and Therapy 1/2016 Go to the issue