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01-06-2019 | Case Report

Vaccine strain Listeria monocytogenes bacteremia occurring 31 months after immunization

Authors: Elias Fares, Cindy B. McCloskey, Andres Gutierrez, Michael Princiotta, Linda J. Salinas, Douglas A. Drevets

Published in: Infection | Issue 3/2019

Abstract

Background

Listeria monocytogenes is a food-borne, facultative intracellular bacterium that causes severe diseases such as sepsis and meningoencephalitis in immunocompromised hosts. Because it stimulates robust T-lymphocyte-mediated responses, attenuated L. monocytogenes are candidate vaccine vectors for tumor immunotherapy.

Case

We report a case of bacteremia caused by vaccine strain L. monocytogenes (Axalimogene filolisbac) occurring 31 months after immunization against human papilloma virus (HPV) associated cervical cancer.

Conclusion

Receipt of a L. monocytogenes-based vaccine is a novel risk factor for delayed L. monocytogenes bacteremia.

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Title: Vaccine strain Listeria monocytogenes bacteremia occurring 31 months after immunization
Authors: Elias Fares
Cindy B. McCloskey
Andres Gutierrez
Michael Princiotta
Linda J. Salinas
Douglas A. Drevets
Publication date: 01-06-2019
Publisher: Springer Berlin Heidelberg
Published in: Infection / Issue 3/2019
Print ISSN: 0300-8126
Electronic ISSN: 1439-0973
DOI: https://doi.org/10.1007/s15010-018-1249-7

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Vaccine strain Listeria monocytogenes bacteremia occurring 31 months after immunization

Abstract

Background

Case

Conclusion

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Abstract

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