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Published in: Infection 3/2017

01-06-2017 | Brief Report

Retrospective analysis of clinical and virological parameters of influenza cases at four university hospitals in Germany, 2015

Authors: Robert Heyd, Anna Maria Eis-Hübinger, Annemarie Berger, Sibylle Bierbaum, Sandra Pietzonka, Jürgen J. Wenzel, Daniela Huzly, Oliver T. Keppler, Marcus Panning

Published in: Infection | Issue 3/2017

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Abstract

We conducted a retrospective observational study at four German university hospitals of patients with laboratory-confirmed influenza in 2014/2015. Overall, a fatality rate of 8% was observed. Significantly more A(H1N1)pdm09 patients were admitted to ICU compared to those with A(H3N2). However, fatal outcome was not significantly increased among A(H1N1)pdm09 cases. Nosocomial infections were seen in 17% of cases. Systematic collection of data from hospitals will complement national influenza surveillance.
Literature
1.
go back to reference Babcock HM, Merz LR, Dubberke ER, Fraser VJ. Case-control study of clinical features of influenza in hospitalized patients. Infect Control Hosp Epidemiol. 2008;29:921–6.CrossRefPubMed Babcock HM, Merz LR, Dubberke ER, Fraser VJ. Case-control study of clinical features of influenza in hospitalized patients. Infect Control Hosp Epidemiol. 2008;29:921–6.CrossRefPubMed
2.
go back to reference Rao S, Torok MR, Bagdure D, et al. A comparison of H1N1 influenza among pediatric inpatients in the pandemic and post pandemic era. J Clin Virol. 2015;71:44–50.CrossRefPubMed Rao S, Torok MR, Bagdure D, et al. A comparison of H1N1 influenza among pediatric inpatients in the pandemic and post pandemic era. J Clin Virol. 2015;71:44–50.CrossRefPubMed
3.
go back to reference Pebody RG, Warburton F, Ellis J, et al. Low effectiveness of seasonal influenza vaccine in preventing laboratory-confirmed influenza in primary care in the United Kingdom: 2014/2015 mid-season results. Euro Surveill. 2015;20:21025.CrossRefPubMed Pebody RG, Warburton F, Ellis J, et al. Low effectiveness of seasonal influenza vaccine in preventing laboratory-confirmed influenza in primary care in the United Kingdom: 2014/2015 mid-season results. Euro Surveill. 2015;20:21025.CrossRefPubMed
4.
go back to reference Huzly D, Kurz S, Ebner W, Dettenkofer M, Panning M. Characterisation of nosocomial and community-acquired influenza in a large university hospital during two consecutive influenza seasons. J Clin Virol. 2015;73:47–51.CrossRefPubMed Huzly D, Kurz S, Ebner W, Dettenkofer M, Panning M. Characterisation of nosocomial and community-acquired influenza in a large university hospital during two consecutive influenza seasons. J Clin Virol. 2015;73:47–51.CrossRefPubMed
5.
go back to reference Hagel S, Ludewig K, Moeser A, et al. Characteristics and management of patients with influenza in a German hospital during the 2014/2015 influenza season. Infection. 2016;44:667–72.CrossRefPubMed Hagel S, Ludewig K, Moeser A, et al. Characteristics and management of patients with influenza in a German hospital during the 2014/2015 influenza season. Infection. 2016;44:667–72.CrossRefPubMed
6.
go back to reference Claus JA, Hodowanec AC, Singh K. Poor positive predictive value of influenza-like illness criteria in adult transplant patients: a case for multiplex respiratory virus PCR testing. Clin Transplant. 2015;29:938–43.CrossRefPubMed Claus JA, Hodowanec AC, Singh K. Poor positive predictive value of influenza-like illness criteria in adult transplant patients: a case for multiplex respiratory virus PCR testing. Clin Transplant. 2015;29:938–43.CrossRefPubMed
7.
go back to reference Giannella M, Rodriguez-Sanchez B, Roa PL, et al. Should lower respiratory tract secretions from intensive care patients be systematically screened for influenza virus during the influenza season? Crit Care. 2012;16:R104.CrossRefPubMedPubMedCentral Giannella M, Rodriguez-Sanchez B, Roa PL, et al. Should lower respiratory tract secretions from intensive care patients be systematically screened for influenza virus during the influenza season? Crit Care. 2012;16:R104.CrossRefPubMedPubMedCentral
8.
go back to reference Dik JW, Poelman R, Friedrich AW, et al. An integrated stewardship model: antimicrobial, infection prevention and diagnostic (AID). Future Microbiol. 2016;11:93–102.CrossRefPubMed Dik JW, Poelman R, Friedrich AW, et al. An integrated stewardship model: antimicrobial, infection prevention and diagnostic (AID). Future Microbiol. 2016;11:93–102.CrossRefPubMed
11.
go back to reference Bauernfeind S, Bruennler T, Ehrenstein B, et al. Pandemic and post-pandemic influenza A (H1N1) seasons in a tertiary care university hospital-high rate of complications compared to previous influenza seasons. Infection. 2013;41:145–50.CrossRefPubMed Bauernfeind S, Bruennler T, Ehrenstein B, et al. Pandemic and post-pandemic influenza A (H1N1) seasons in a tertiary care university hospital-high rate of complications compared to previous influenza seasons. Infection. 2013;41:145–50.CrossRefPubMed
12.
go back to reference Minchole E, Figueredo AL, Omenaca M, et al. Seasonal influenza A H1N1pdm09 virus and severe outcomes: a reason for broader vaccination in non-elderly, at-risk people. PLoS ONE. 2016;11:e0165711.CrossRefPubMedPubMedCentral Minchole E, Figueredo AL, Omenaca M, et al. Seasonal influenza A H1N1pdm09 virus and severe outcomes: a reason for broader vaccination in non-elderly, at-risk people. PLoS ONE. 2016;11:e0165711.CrossRefPubMedPubMedCentral
Metadata
Title
Retrospective analysis of clinical and virological parameters of influenza cases at four university hospitals in Germany, 2015
Authors
Robert Heyd
Anna Maria Eis-Hübinger
Annemarie Berger
Sibylle Bierbaum
Sandra Pietzonka
Jürgen J. Wenzel
Daniela Huzly
Oliver T. Keppler
Marcus Panning
Publication date
01-06-2017
Publisher
Springer Berlin Heidelberg
Published in
Infection / Issue 3/2017
Print ISSN: 0300-8126
Electronic ISSN: 1439-0973
DOI
https://doi.org/10.1007/s15010-017-1008-1

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