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Published in: Infection 3/2014

01-06-2014 | Case Report

Chronic necrotizing pulmonary aspergillosis in an immunocompetent patient: report of a rare case

Authors: E. Jin, L. M. Wang, Q. Y. Li, X. Feng, S. L. Ma

Published in: Infection | Issue 3/2014

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Abstract

Chronic necrotizing pulmonary aspergillosis (CNPA) is a relatively uncommon manifestation of infection with Aspergillus spp. which mainly affects immunocompromised or immunostressed individuals with underlying lung diseases. Here, we present a case of mediastinum-involved CNPA in an immunocompetent patient with no symptoms and previous good health.
Literature
1.
go back to reference Parra I, Remacha A, Rezusta A, et al. Chronic necrotizing pulmonary aspergillosis. Med Mycol. 2004;42:369–71.PubMedCrossRef Parra I, Remacha A, Rezusta A, et al. Chronic necrotizing pulmonary aspergillosis. Med Mycol. 2004;42:369–71.PubMedCrossRef
2.
go back to reference Brown GD, Denning DW, Gow NA, Levitz SM, Netea MG, White TC. Hidden killers: human fungal infections. Sci Transl Med. 2012;4:165rv13.PubMedCrossRef Brown GD, Denning DW, Gow NA, Levitz SM, Netea MG, White TC. Hidden killers: human fungal infections. Sci Transl Med. 2012;4:165rv13.PubMedCrossRef
3.
go back to reference Smith NL, Denning DW. Underlying conditions in chronic pulmonary aspergillosis including simple aspergilloma. Eur Respir J. 2011;37:865–72.PubMedCrossRef Smith NL, Denning DW. Underlying conditions in chronic pulmonary aspergillosis including simple aspergilloma. Eur Respir J. 2011;37:865–72.PubMedCrossRef
4.
go back to reference Franquet T, Müller NL, Giménez A, Domingo P, Plaza V, Bordes R. Semiinvasive pulmonary aspergillosis in chronic obstructive pulmonary disease: radiologic and pathologic findings in nine patients. Am J Roentgenol. 2000;174:51–6.CrossRef Franquet T, Müller NL, Giménez A, Domingo P, Plaza V, Bordes R. Semiinvasive pulmonary aspergillosis in chronic obstructive pulmonary disease: radiologic and pathologic findings in nine patients. Am J Roentgenol. 2000;174:51–6.CrossRef
5.
go back to reference Shakoor MT, Ayub S, Ayub Z, Mahmood F. Fulminant invasive aspergillosis of the mediastinum in an immunocompetent host: a case report. J Med Case Rep. 2012;6:311.PubMedCentralPubMedCrossRef Shakoor MT, Ayub S, Ayub Z, Mahmood F. Fulminant invasive aspergillosis of the mediastinum in an immunocompetent host: a case report. J Med Case Rep. 2012;6:311.PubMedCentralPubMedCrossRef
6.
go back to reference Sridhar V, Rajagopalan N, Shivaprasad C, Patil M, Varghese J. Acute community acquired Aspergillus pneumonia in a presumed immunocompetent host. BMJ Case Rep. 2012;. doi:10.1136/bcr.09.2011.4866 (pii): bcr0920114866. Sridhar V, Rajagopalan N, Shivaprasad C, Patil M, Varghese J. Acute community acquired Aspergillus pneumonia in a presumed immunocompetent host. BMJ Case Rep. 2012;. doi:10.​1136/​bcr.​09.​2011.​4866 (pii): bcr0920114866.
7.
go back to reference Maschmeyer G, Haas A, Cornely OA. Invasive aspergillosis: epidemiology, diagnosis and management in immunocompromised patients. Drugs. 2007;67:1567–601.PubMedCrossRef Maschmeyer G, Haas A, Cornely OA. Invasive aspergillosis: epidemiology, diagnosis and management in immunocompromised patients. Drugs. 2007;67:1567–601.PubMedCrossRef
8.
go back to reference Jung SW, Kim MW, Cho SK, Kim HU, Lee DC, Yoon BK, Jeong JP, Ko YC. A case of endobronchial aspergilloma associated with foreign body in immunocompetent patient without underlying lung disease. Tuberc Respir Dis (Seoul). 2013;74:231–4.CrossRef Jung SW, Kim MW, Cho SK, Kim HU, Lee DC, Yoon BK, Jeong JP, Ko YC. A case of endobronchial aspergilloma associated with foreign body in immunocompetent patient without underlying lung disease. Tuberc Respir Dis (Seoul). 2013;74:231–4.CrossRef
9.
go back to reference Chien WL, Tseng JS. Pulmonary aspergillosis in an immunocompetent patient. Braz J Infect Dis. 2013;17:375–6.PubMedCrossRef Chien WL, Tseng JS. Pulmonary aspergillosis in an immunocompetent patient. Braz J Infect Dis. 2013;17:375–6.PubMedCrossRef
11.
12.
go back to reference Kang EY, Kim DH, Woo OH, et al. Pulmonary aspergillosis in immunocompetent hosts without underlying lesions of the lung: radiologic and pathologic findings. Am J Roentgenol. 2002;178:1395–9.CrossRef Kang EY, Kim DH, Woo OH, et al. Pulmonary aspergillosis in immunocompetent hosts without underlying lesions of the lung: radiologic and pathologic findings. Am J Roentgenol. 2002;178:1395–9.CrossRef
13.
go back to reference Yoon SH, Park CM, Goo JM, Lee HJ. Pulmonary aspergillosis in immunocompetent patients without air-meniscus sign and underlying lung disease: CT findings and histopathologic features. Acta Radiol. 2011;52:756–61.PubMedCrossRef Yoon SH, Park CM, Goo JM, Lee HJ. Pulmonary aspergillosis in immunocompetent patients without air-meniscus sign and underlying lung disease: CT findings and histopathologic features. Acta Radiol. 2011;52:756–61.PubMedCrossRef
14.
go back to reference Yoshida K, Kurashima A, Kamei K, Oritsu M, Ando T, Yamamoto T, Niki Y. Efficacy and safety of short- and long-term treatment of itraconazole on chronic necrotizing pulmonary aspergillosis in multicenter study. J Infect Chemother. 2012;18:378–85.PubMedCrossRef Yoshida K, Kurashima A, Kamei K, Oritsu M, Ando T, Yamamoto T, Niki Y. Efficacy and safety of short- and long-term treatment of itraconazole on chronic necrotizing pulmonary aspergillosis in multicenter study. J Infect Chemother. 2012;18:378–85.PubMedCrossRef
15.
go back to reference Soubani AO, Chandrasekar PH. The clinical spectrum of pulmonary aspergillosis. Chest. 2002;121:1988–99.PubMedCrossRef Soubani AO, Chandrasekar PH. The clinical spectrum of pulmonary aspergillosis. Chest. 2002;121:1988–99.PubMedCrossRef
Metadata
Title
Chronic necrotizing pulmonary aspergillosis in an immunocompetent patient: report of a rare case
Authors
E. Jin
L. M. Wang
Q. Y. Li
X. Feng
S. L. Ma
Publication date
01-06-2014
Publisher
Springer Berlin Heidelberg
Published in
Infection / Issue 3/2014
Print ISSN: 0300-8126
Electronic ISSN: 1439-0973
DOI
https://doi.org/10.1007/s15010-013-0575-z

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