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Acta Neurologica Belgica
Published in: Acta Neurologica Belgica 1/2017

01-03-2017 | Letter to the Editor

Neurological deterioration in the treatment of Herpes zoster: encephalitis or neurotoxic effect of acyclovir?

Authors: H. De Cauwer, Jan Maes, M. Viaene, L. Janssen, L. Belmans

Published in: Acta Neurologica Belgica | Issue 1/2017

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Excerpt

Herpes zoster (VZV) infections have an annual incidence of approximately 1.5–3/1000 inhabitants. For Belgium, this means an annual incidence of about 20,000 cases. VZV affects mainly the elderly population [1]. …
Literature
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Gregoire SM, van Pesch V, Goffette S, Peeters A, Sindic CJM (2006) Polymerase chain reaction analysis and oligoclonal antibody in the cerebrospinal fluid from 34 patients with varicella-zoster virus infection of the nervous system. J Neurol Neurosurg Psychiatry 77:938–942CrossRefPubMedPubMedCentral
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Haargaard B, Lund-Andersen H, Milea D (2008) Central nervous system involvement after herpes zoster ophtalmicus. Acta Ophtalmol 86:806–809CrossRef
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Sacchetti D, Alawadhi A, Albakour M, Rapose A (2014) Herpes zoster encephalopathy or acyclovir neurotoxicity: a management dilemma. BMJ Case Rep 28:2014
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Chowdhury MA, Derar N, Hasan S, Hinch B, Ratnam S, Assaly R (2016) Acyclovir-induced neurotoxicity: a case report and review of literature. Am J Ther 23:e941–e943CrossRefPubMed
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Levy M, Hentgen V, Marque-Juillet S, Fiot E, Fagherazzi G, Nathanson S et al (2015) Prognostic value of VZV PCR in cerebrospinal fluid in neurological manifestations of varicella. Arch Pediatr 22:491–497CrossRefPubMed
Metadata
Title
Neurological deterioration in the treatment of Herpes zoster: encephalitis or neurotoxic effect of acyclovir?
Authors
H. De Cauwer
Jan Maes
M. Viaene
L. Janssen
L. Belmans
Publication date
01-03-2017
Publisher
Springer International Publishing
Published in
Acta Neurologica Belgica / Issue 1/2017
Print ISSN: 0300-9009
Electronic ISSN: 2240-2993
DOI
https://doi.org/10.1007/s13760-016-0670-x

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