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Published in: CEN Case Reports 1/2015

01-05-2015 | Case Report

Henoch–Schönlein purpura complicated with severe gastrointestinal bleeding

Authors: Tomoyuki Yamazaki, Tetsu Akimoto, Yoshitaka Iwazu, Taro Sugase, Eri Takeshima, Akihiko Numata, Takanori Komada, Hiromichi Yoshizawa, Naoko Otani, Yoshiyuki Morishita, Osamu Saito, Fumi Takemoto, Shigeaki Muto, Eiji Kusano, Daisuke Nagata

Published in: CEN Case Reports | Issue 1/2015

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Abstract

Bleeding from the gastrointestinal tract is one of the common determinants of morbidity and mortality in the ordinary clinical setting. The gastrointestinal involvement of Henoch–Schönlein purpura (HSP) has often been described as self-limiting, with no long-term morbidity. In this report, we describe our experience with a male HSP patient who presented with abdominal pain, loss of appetite and deteriorated renal function associated with nephrotic syndrome. Despite the use of aggressive immunomodulatory treatments, including corticosteroids and plasmapheresis, he developed lethal gastrointestinal hemorrhage. We believe that the accumulation of more experience with additional cases similar to ours is mandatory for the establishment of optimal management for HSP patients with severe gastrointestinal manifestations.
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Metadata
Title
Henoch–Schönlein purpura complicated with severe gastrointestinal bleeding
Authors
Tomoyuki Yamazaki
Tetsu Akimoto
Yoshitaka Iwazu
Taro Sugase
Eri Takeshima
Akihiko Numata
Takanori Komada
Hiromichi Yoshizawa
Naoko Otani
Yoshiyuki Morishita
Osamu Saito
Fumi Takemoto
Shigeaki Muto
Eiji Kusano
Daisuke Nagata
Publication date
01-05-2015
Publisher
Springer Japan
Published in
CEN Case Reports / Issue 1/2015
Electronic ISSN: 2192-4449
DOI
https://doi.org/10.1007/s13730-014-0148-8

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