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Dermatology and Therapy
Published in: Dermatology and Therapy 2/2016

Open Access 01-06-2016 | Review

Burden of Moderate-to-Severe Plaque Psoriasis and New Therapeutic Approaches (Secukinumab): An Italian Perspective

Authors: Lorenzo Mantovani, Massimo Medaglia, Patrizio Piacentini, Marcella Tricca, Gino Antonio Vena, Antonietta Vozza, Gabriella Castellino, Alessandro Roccia

Published in: Dermatology and Therapy | Issue 2/2016

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Abstract

Psoriasis is a chronic immune-mediated inflammatory skin disease commonly categorized as mild, moderate, or severe. Moderate-to-severe psoriasis is associated with significant comorbidity and has been shown to severely impair quality of life. Moreover, psoriasis is associated with high costs, including those associated with treatment, which have increased recently with the inclusion of biological systemic agents (most recently secukinumab) as available treatment options. However, despite clear evidence of their value in the treatment of moderate-to-severe plaque psoriasis, in Italy access to the biological agents remains limited to dermatological centers originally involved in the Psocare network. The impact of secukinumab entry into the market in Italy is still to be determined, but we believe that it will be associated with significant changes in the way in which biological treatments for psoriasis are accessed and prescribed in Italy. It is noteworthy that in January 2015, the European Medicines Agency approved secukinumab as first-line systemic therapy in this indication.

Funding

Novartis, Italy.
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Metadata
Title
Burden of Moderate-to-Severe Plaque Psoriasis and New Therapeutic Approaches (Secukinumab): An Italian Perspective
Authors
Lorenzo Mantovani
Massimo Medaglia
Patrizio Piacentini
Marcella Tricca
Gino Antonio Vena
Antonietta Vozza
Gabriella Castellino
Alessandro Roccia
Publication date
01-06-2016
Publisher
Springer Healthcare
Published in
Dermatology and Therapy / Issue 2/2016
Print ISSN: 2193-8210
Electronic ISSN: 2190-9172
DOI
https://doi.org/10.1007/s13555-016-0114-9

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