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Journal of Cachexia, Sarcopenia and Muscle
Published in: Journal of Cachexia, Sarcopenia and Muscle 4/2014

01-12-2014 | Editorial

Prevalence, incidence, and clinical impact of sarcopenia: facts, numbers, and epidemiology—update 2014

Authors: John E. Morley, Stefan D. Anker, Stephan von Haehling

Published in: Journal of Cachexia, Sarcopenia and Muscle | Issue 4/2014

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Abstract

Sarcopenia is now defined as a decline in walking speed or grip strength associated with low muscle mass. Sarcopenia leads to loss of mobility and function, falls, and mortality. Sarcopenia is a major cause of frailty, but either condition can occur without the other being present. Sarcopenia is present in about 5 to 10 % of persons over 65 years of age. It has multiple causes including disease, decreased caloric intake, poor blood flow to muscle, mitochondrial dysfunction, a decline in anabolic hormones, and an increase in proinflammatory cytokines. Basic therapy includes resistance exercise and protein and vitamin D supplementation. There is now a simple screening test available for sarcopenia—SARC-F. All persons 60 years and older should be screened for sarcopenia and treated when appropriate.
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Metadata
Title
Prevalence, incidence, and clinical impact of sarcopenia: facts, numbers, and epidemiology—update 2014
Authors
John E. Morley
Stefan D. Anker
Stephan von Haehling
Publication date
01-12-2014
Publisher
Springer Berlin Heidelberg
Published in
Journal of Cachexia, Sarcopenia and Muscle / Issue 4/2014
Print ISSN: 2190-5991
Electronic ISSN: 2190-6009
DOI
https://doi.org/10.1007/s13539-014-0161-y

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