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International Journal of Diabetes in Developing Countries

Published in:

01-11-2015 | Original Article

Comparison of salivary nitric oxide and epidermal growth factor level between diabetic patients and healthy individuals

Authors: Hamid Reza Abdolsamadi, Fatemeh Rezaei, Mohammad Taghi Goodarzi, Abbas Moghimbeigi, Mina Jazaeri, Soheila Asadi, Fatemeh Ahmadi-Motamayel

Published in: International Journal of Diabetes in Developing Countries | Special Issue 3/2015

Abstract

The purpose of the current study was to compare salivary Nitric oxide and epidermal growth factor level in diabetic patients and healthy individuals. In this paired-control study 20 patients with type 1 diabetes mellitus, 20 patients with type 2 diabetes mellitus and 20 age and sex matched healthy subjects participated. The level of salivary Nitric oxide was increased in type 1 and 2 diabetic patients in comparison to control individuals (P = 0.037 and P = 0.058), respectively. Epidermal growth factor concentration was higher in type 1 and 2 diabetic patients compare to healthy ones, (P = 0.037 and P = 0.005) respectively. There was no significant difference between salivary Nitric oxide and Epidermal growth factor level regarding to the type of diabetes (P > 0.05). Significant statistical correlation was found between Nitric oxide and Epidermal growth factor levels and the fasting blood glucose and HbA1c (P < 0.001). Conclusions: Salivary Nitric oxide and Epidermal growth factor levels were higher in type 1 and type 2 diabetic patients and there was correlation with severity of disease.

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Title: Comparison of salivary nitric oxide and epidermal growth factor level between diabetic patients and healthy individuals
Authors: Hamid Reza Abdolsamadi
Fatemeh Rezaei
Mohammad Taghi Goodarzi
Abbas Moghimbeigi
Mina Jazaeri
Soheila Asadi
Fatemeh Ahmadi-Motamayel
Publication date: 01-11-2015
Publisher: Springer India
Published in: International Journal of Diabetes in Developing Countries / Issue Special Issue 3/2015
Print ISSN: 0973-3930
Electronic ISSN: 1998-3832
DOI: https://doi.org/10.1007/s13410-014-0207-x

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