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International Journal of Diabetes in Developing Countries

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01-12-2012 | Editorial

Antioxidants for clinical use

Author: K. M. Prasanna Kumar

Published in: International Journal of Diabetes in Developing Countries | Issue 4/2012

Excerpt

Free radicals are molecules, which lack an electron in their chemical structure, which they constantly try to replace. The free radicals try to get electrons from the body, which causes “oxidative stress,” which in turn results in damage to the body’s cells and tissues. Antioxidants provide the extra electrons to the free radicals and prevent them from causing damage to the body’s cells and tissues. Since world war II the free radicals biochemistry came into vogue. Free radicals have been implicated in the etiology of several human diseases as well as ageing [1, 2]. …

Harman D. Ageing: a theory based on free radical and radiation chemistry. J Gerontol. 1956;11:298–300.PubMedCrossRef

Halliwell B, Gutteridge JMC, editors. Free radicals in biology and medicine. Oxford: Oxford University Press; 1997.

Halliwell B, Gutreridge JMC. Free radicals in biology and medicine. 2nd ed. Oxford: Clarendon Press; 1989.

Devasagayam TPA, Tilak JC, Boloor KK, Sane KS, Ghaskadbi SS, Lele RD. Free radicals and antioxidants in human health: current status and future prospects. JAPI. 2004;52:794–804.PubMed

Krishnaswami K. Indian functional food: role in prevention of cancer. Nutr Rev. 1996;54:S127–31.CrossRef

Panchal SS. Anti-diabetic activity of oryzanol and its relationship with the anti-oxidant property. Int J Diab Dev Ctries. doi:10.1007/s13410-012-0086-y.

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Golbidi S, Ebadi SA, Laher I. Antioxidants in the treatment of diabetes. Curr Diabetes Rev. 2011;7:106–25.PubMedCrossRef

Weber AC, Ernst ME. Drug information rounds-antioxidants, supplements and parkinson’s disease. Ann Pharmacother. 2006;40:935–8.PubMedCrossRef

Title: Antioxidants for clinical use
Author: K. M. Prasanna Kumar
Publication date: 01-12-2012
Publisher: Springer-Verlag
Published in: International Journal of Diabetes in Developing Countries / Issue 4/2012
Print ISSN: 0973-3930
Electronic ISSN: 1998-3832
DOI: https://doi.org/10.1007/s13410-012-0095-x

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Excerpt

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Young inflorescence of Cocos nucifera contributes to improvement of glucose homeostasis and antioxidant status in diabetic rats

Evaluation of plasma fibrinogen levels in type 2 diabetes mellitus

Relationship between proinsulin and beta cell function in different states of glucose tolerance

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