Skip to main content
Top
Published in: Journal of NeuroVirology 3/2023

09-05-2023 | Human Immunodeficiency Virus | Case Report

Cognitive function and impact on driving after SARS-COV-2 infection in a man with long-standing HIV infection: a case report

Authors: Juan Gonzalez, Neil Patel, Raymond L. Ownby

Published in: Journal of NeuroVirology | Issue 3/2023

Login to get access

Abstract

A substantial number of individuals who experience COVID-19 infection experience prolonged physical and mental symptoms after resolution of their initial infection, and among them, many individuals experience cognitive difficulties including memory lapses and executive function difficulties, often referred to as “brain fog.” The possible impact of COVID-19 infection on cognition in persons with HIV-related cognitive disorders is unknown. In this report, we describe post-COVID-19 cognitive and driving function in a 62-year-old man with HIV infection since the early 1990s.
Literature
go back to reference Antinori A, Arendt G, Becker JT, Brew BJ, Byrd DA, Cherner M, Clifford DB, Cinque P, Epstein LG, Goodkin K, Gisslen M, Grant I, Heaton RK, Joseph J, Marder K, Marra CM, McArthur JC, Nunn M, Price RW, Pulliam L, Robertson KR, Sacktor N, Valcour V, Wojna VE (2007) Updated research nosology for HIV-associated neurocognitive disorders. Neurology 69:1789–1799CrossRefPubMed Antinori A, Arendt G, Becker JT, Brew BJ, Byrd DA, Cherner M, Clifford DB, Cinque P, Epstein LG, Goodkin K, Gisslen M, Grant I, Heaton RK, Joseph J, Marder K, Marra CM, McArthur JC, Nunn M, Price RW, Pulliam L, Robertson KR, Sacktor N, Valcour V, Wojna VE (2007) Updated research nosology for HIV-associated neurocognitive disorders. Neurology 69:1789–1799CrossRefPubMed
go back to reference Ceban F, Ling S, Lui LMW, Lee Y, Gill H, Teopiz KM, Rodrigues NB, Subramaniapillai M, Di Vincenzo JD, Cao B, Lin K, Mansur RB, Ho RC, Rosenblat JD, Miskowiak KW, Vinberg M, Maletic V, McIntyre RS (2022) Fatigue and cognitive impairment in post-COVID-19 syndrome: a systematic review and meta-analysis. Brain Behav Immun 101:93–135CrossRefPubMed Ceban F, Ling S, Lui LMW, Lee Y, Gill H, Teopiz KM, Rodrigues NB, Subramaniapillai M, Di Vincenzo JD, Cao B, Lin K, Mansur RB, Ho RC, Rosenblat JD, Miskowiak KW, Vinberg M, Maletic V, McIntyre RS (2022) Fatigue and cognitive impairment in post-COVID-19 syndrome: a systematic review and meta-analysis. Brain Behav Immun 101:93–135CrossRefPubMed
go back to reference Dawson JD, Uc EY, Anderson SW, Johnson AM, Rizzo M (2010) Neuropsychological predictors of driving errors in older adults. J Am Geriatr Soc 58:1090–1096CrossRefPubMedPubMedCentral Dawson JD, Uc EY, Anderson SW, Johnson AM, Rizzo M (2010) Neuropsychological predictors of driving errors in older adults. J Am Geriatr Soc 58:1090–1096CrossRefPubMedPubMedCentral
go back to reference Foley JM, Gooding AL, Thames AD, Ettenhofer ML, Kim MS, Castellon SA, Marcotte TD, Sadek JR, Heaton RK, van Gorp WG, Hinkin CH (2013) Visuospatial and attentional abilities predict driving simulator performance among older HIV-infected adults. Am J Alzheimers Dis Other Demen 28:185–194CrossRefPubMedPubMedCentral Foley JM, Gooding AL, Thames AD, Ettenhofer ML, Kim MS, Castellon SA, Marcotte TD, Sadek JR, Heaton RK, van Gorp WG, Hinkin CH (2013) Visuospatial and attentional abilities predict driving simulator performance among older HIV-infected adults. Am J Alzheimers Dis Other Demen 28:185–194CrossRefPubMedPubMedCentral
go back to reference Groeger JA, Murphy G (2020) Driver performance under simulated and actual driving conditions: validity and orthogonality. Accid Anal Prev 143:105593CrossRefPubMed Groeger JA, Murphy G (2020) Driver performance under simulated and actual driving conditions: validity and orthogonality. Accid Anal Prev 143:105593CrossRefPubMed
go back to reference Heaton RK, Clifford DB, Franklin DR Jr, Woods SP, Ake C, Vaida F, Ellis RJ, Letendre SL, Marcotte TD, Atkinson JH, Rivera-Mindt M, Vigil OR, Taylor MJ, Collier AC, Marra CM, Gelman BB, McArthur JC, Morgello S, Simpson DM, McCutchan JA, Abramson I, Gamst A, Fennema-Notestine C, Jernigan TL, Wong J, Grant I (2010) HIV-associated neurocognitive disorders persist in the era of potent antiretroviral therapy: CHARTER Study. Neurology 75:2087–2096CrossRefPubMedPubMedCentral Heaton RK, Clifford DB, Franklin DR Jr, Woods SP, Ake C, Vaida F, Ellis RJ, Letendre SL, Marcotte TD, Atkinson JH, Rivera-Mindt M, Vigil OR, Taylor MJ, Collier AC, Marra CM, Gelman BB, McArthur JC, Morgello S, Simpson DM, McCutchan JA, Abramson I, Gamst A, Fennema-Notestine C, Jernigan TL, Wong J, Grant I (2010) HIV-associated neurocognitive disorders persist in the era of potent antiretroviral therapy: CHARTER Study. Neurology 75:2087–2096CrossRefPubMedPubMedCentral
go back to reference Lafayette Instrument Company (2002) Grooved Pegboard Test user instructions. Lafayette Instrument Company: Lafayette IN Lafayette Instrument Company (2002) Grooved Pegboard Test user instructions. Lafayette Instrument Company: Lafayette IN
go back to reference Ownby RL, Kim J (2021) Computer-delivered cognitive training and transcranial direct current stimulation in patients with HIV-associated neurocognitive disorder: a randomized trial. Front Aging Neurosci 13:766311 Ownby RL, Kim J (2021) Computer-delivered cognitive training and transcranial direct current stimulation in patients with HIV-associated neurocognitive disorder: a randomized trial. Front Aging Neurosci 13:766311
go back to reference Papandonatos GD, Ott BR, Davis JD, Barco PP, Carr DB (2015) Clinical utility of the Trail-Making Test as a predictor of driving performance in older adults. J Am Geriatr Soc 63:2358–2364CrossRefPubMedPubMedCentral Papandonatos GD, Ott BR, Davis JD, Barco PP, Carr DB (2015) Clinical utility of the Trail-Making Test as a predictor of driving performance in older adults. J Am Geriatr Soc 63:2358–2364CrossRefPubMedPubMedCentral
go back to reference Reitan RM, Wolfson D (1993) The Halstead-Reitan neuropsychological test battery: theory and clinical interpretation. Neuropsychology Press, Tucson AZ Reitan RM, Wolfson D (1993) The Halstead-Reitan neuropsychological test battery: theory and clinical interpretation. Neuropsychology Press, Tucson AZ
go back to reference Thomas-Purcell K, Davenport R, Ayala V, Purcell D, Ownby RL (2023) Chronic disease self-management of post-acute sequelae of COVID-19 among older adults: a mixed-methods analysis. Clin Interv Aging 18:607–617CrossRef Thomas-Purcell K, Davenport R, Ayala V, Purcell D, Ownby RL (2023) Chronic disease self-management of post-acute sequelae of COVID-19 among older adults: a mixed-methods analysis. Clin Interv Aging 18:607–617CrossRef
go back to reference Vance DE, Cody SL, Nicholson WC, Cheatwood J, Morrison S, Fazeli PL (2019) The association between olfactory function and cognition in aging African American and Caucasian men with HIV: a pilot study. J Assoc Nurses AIDS Care 30:e144–e155CrossRefPubMed Vance DE, Cody SL, Nicholson WC, Cheatwood J, Morrison S, Fazeli PL (2019) The association between olfactory function and cognition in aging African American and Caucasian men with HIV: a pilot study. J Assoc Nurses AIDS Care 30:e144–e155CrossRefPubMed
go back to reference Vingilis E, Johnson J, Rapoport MJ, Beirness D, Boase P, Byrne PA, Jonah B, Mann RE, Seeley J, Wickens CM, Wiesenthal DL (2021) Addendum - coronavirus disease 2019: what could be the effects on road safety? Accident; Analysis and Prevention 149:105712–105712CrossRefPubMed Vingilis E, Johnson J, Rapoport MJ, Beirness D, Boase P, Byrne PA, Jonah B, Mann RE, Seeley J, Wickens CM, Wiesenthal DL (2021) Addendum - coronavirus disease 2019: what could be the effects on road safety? Accident; Analysis and Prevention 149:105712–105712CrossRefPubMed
go back to reference Wechsler D (2008). Manual for the Wechsler Adult Intelligence Scale--IV. Pearson Assessment: San Antonio TX Wechsler D (2008). Manual for the Wechsler Adult Intelligence Scale--IV. Pearson Assessment: San Antonio TX
Metadata
Title
Cognitive function and impact on driving after SARS-COV-2 infection in a man with long-standing HIV infection: a case report
Authors
Juan Gonzalez
Neil Patel
Raymond L. Ownby
Publication date
09-05-2023
Publisher
Springer International Publishing
Published in
Journal of NeuroVirology / Issue 3/2023
Print ISSN: 1355-0284
Electronic ISSN: 1538-2443
DOI
https://doi.org/10.1007/s13365-023-01143-1

Other articles of this Issue 3/2023

Journal of NeuroVirology 3/2023 Go to the issue