Skip to main content
Top
Published in: Diabetology International 1/2021

01-01-2021 | Gingival Diseases | Report of the Committee

A large-scale observational study to investigate the current status of diabetic complications and their prevention in Japan (JDCP study 6): baseline dental and oral findings

Authors: Koji Inagaki, Takeshi Kikuchi, Toshihide Noguchi, Akio Mitani, Keiko Naruse, Tatsuaki Matsubara, Masamitsu Kawanami, Jun Negishi, Yasushi Furuichi, Eiji Nemoto, Satoru Yamada, Hiromasa Yoshie, Koichi Tabeta, Sachiyo Tomita, Atsushi Saito, Sayaka Katagiri, Yuichi Izumi, Hiroshi Nitta, Takanori Iwata, Yukihiro Numabe, Matsuo Yamamoto, Nobuo Yoshinari, Tsuyoshi Fujita, Hidemi Kurihara, Fusanori Nishimura, Toshihiko Nagata, Hiromichi Yumoto, Toru Naito, Kazuyuki Noguchi, Koichi Ito, Shinya Murakami, Rimei Nishimura, Naoko Tajima

Published in: Diabetology International | Issue 1/2021

Login to get access

Abstract

Japan Diabetes Complication and Prevention prospective (JDCP) study was conducted to examine the association between glycemic control and oral conditions in a large database of Japanese patients with diabetes. It included a total of 6099 patients with diabetes (range, 40–75 years) who had been treated as outpatients between 2007 and 2009. The mean number of present teeth at baseline was 19.8 and women with type 2 diabetes had fewer teeth than men with type 2 diabetes. Within the previous year, 17% of all patients had lost teeth. At baseline, 32% had experienced gingival swelling, 69% had brushed more than twice a day, 37% had used interdental cleaning aids, and 43% had undergone regular dental checkups. Multiple logistic regression analysis indicated that type 1 patients with HbA1c ≥ 7.0% were at higher risk of having fewer than 20 teeth (odds ratio [OR] 2.38; 95% confidence interval [CI] 1.25–4.78), and type 2 patients with HbA1c ≥ 8.0% also were at high risk of having fewer than 20 teeth (OR 1.16; 95% CI 1.00–1.34), after adjustment for nine possible confounding factors. In conclusion, patients with diabetes were found to be at high risk of tooth loss, and the poorer the glycemic control, the higher the risk of tooth loss in these patients.
Literature
1.
go back to reference Inagaki K, Kikuchi T, Noguchi T, et al. A Large-scale Observational Study to Investigate the Current Status of Diabetic Complication and Their Prevention in Japan (JDCP study 6): Baseline Dental and Oral Findings. J Jpn Diabet Soc. 2020;63(4):195–205 (in Japanese). Inagaki K, Kikuchi T, Noguchi T, et al. A Large-scale Observational Study to Investigate the Current Status of Diabetic Complication and Their Prevention in Japan (JDCP study 6): Baseline Dental and Oral Findings. J Jpn Diabet Soc. 2020;63(4):195–205 (in Japanese).
2.
go back to reference Williams RC, Offenbacher S. Periodontal medicine: the emergence of a new branch of periodontology. Periodontol. 2000;23:9–12.CrossRef Williams RC, Offenbacher S. Periodontal medicine: the emergence of a new branch of periodontology. Periodontol. 2000;23:9–12.CrossRef
3.
go back to reference Japanese Society of Periodontology (2016) JSP Clinical Practice Guideline for Periodontal Treatment 2015, Ishiyaku Pub Inc., Tokyo, pp 8–17 (in Japanese) Japanese Society of Periodontology (2016) JSP Clinical Practice Guideline for Periodontal Treatment 2015, Ishiyaku Pub Inc., Tokyo, pp 8–17 (in Japanese)
4.
go back to reference Japanese Society of Periodontology (2015) JSP Clinical Practice Guideline for Periodontal Treatment in Diabetic Patients 2014, 2nd Edition, Ishiyaku Pub Inc., Tokyo, pp 12–23 (in Japanese) Japanese Society of Periodontology (2015) JSP Clinical Practice Guideline for Periodontal Treatment in Diabetic Patients 2014, 2nd Edition, Ishiyaku Pub Inc., Tokyo, pp 12–23 (in Japanese)
5.
go back to reference Japanese Society of Periodontology (2016) Periodontal Disease and Systemic Health, Ishiyaku Pub Inc., Tokyo, pp 88–91 (in Japanese) Japanese Society of Periodontology (2016) Periodontal Disease and Systemic Health, Ishiyaku Pub Inc., Tokyo, pp 88–91 (in Japanese)
6.
go back to reference Japan Diabetes Society (2019) Clinical Practice Guidelines for Treatment of Diabetes 2019, Nankodo Co., Ltd., Tokyo, pp 24–27, 219–228 (in Japanese) Japan Diabetes Society (2019) Clinical Practice Guidelines for Treatment of Diabetes 2019, Nankodo Co., Ltd., Tokyo, pp 24–27, 219–228 (in Japanese)
11.
go back to reference Borgnakke WS, Ylöstalo PV, Taylor GW, Genco RJ. Effect of periodontal disease on diabetes: systematic review of epidemiologic observational evidence. J Periodontol. 2013;84(4 Suppl):S135–152.PubMed Borgnakke WS, Ylöstalo PV, Taylor GW, Genco RJ. Effect of periodontal disease on diabetes: systematic review of epidemiologic observational evidence. J Periodontol. 2013;84(4 Suppl):S135–152.PubMed
12.
go back to reference Graziani F, Gennai S, Solini A, Petrini M. A systematic review and meta-analysis of epidemiologic observational evidence on the effect of periodontitis on diabetes. An update of the EFP-AAP review. J Clin Periodontol. 2018;45(2):167–87.CrossRef Graziani F, Gennai S, Solini A, Petrini M. A systematic review and meta-analysis of epidemiologic observational evidence on the effect of periodontitis on diabetes. An update of the EFP-AAP review. J Clin Periodontol. 2018;45(2):167–87.CrossRef
13.
go back to reference Inagaki K, Kikuchi T, Mitani A, Naruse K, Matsubara T. Prevention of diabetic complications, periodontal disease. Naika (Intern Med). 2018;212(1):121–6 (in Japanese). Inagaki K, Kikuchi T, Mitani A, Naruse K, Matsubara T. Prevention of diabetic complications, periodontal disease. Naika (Intern Med). 2018;212(1):121–6 (in Japanese).
14.
go back to reference Shlossman M, Knowler WC, Pettitt DJ, Genco RJ. Type 2 diabetes mellitus and periodontal disease. J Am Dent Assoc. 1990;121(4):532–6.CrossRef Shlossman M, Knowler WC, Pettitt DJ, Genco RJ. Type 2 diabetes mellitus and periodontal disease. J Am Dent Assoc. 1990;121(4):532–6.CrossRef
15.
go back to reference Emrich LJ, Shlossman M, Genco RJ. Periodontal disease in non-insulin-dependent diabetes mellitus. J Periodontal. 1991;62(2):123–31.CrossRef Emrich LJ, Shlossman M, Genco RJ. Periodontal disease in non-insulin-dependent diabetes mellitus. J Periodontal. 1991;62(2):123–31.CrossRef
16.
go back to reference Morita I, Inagaki K, Nkamura F, Noguchi T, Matsubara T, Yoshii S, Nakagaki H, Mizuno K, Sheiham A, Sabbah W. Relationship between periodontal status and levels of glycated hemoglobin. J Dent Res. 2012;91(2):161–6.CrossRef Morita I, Inagaki K, Nkamura F, Noguchi T, Matsubara T, Yoshii S, Nakagaki H, Mizuno K, Sheiham A, Sabbah W. Relationship between periodontal status and levels of glycated hemoglobin. J Dent Res. 2012;91(2):161–6.CrossRef
17.
go back to reference Council for Promotion of Countermeasures against Diabetes (Japan Medical Association, Japan Diabetes Society, Japan Association for Diabetes Education and Care) (2017) Essentials of Diabetes Treatment 2017, Bunkodo Co., Ltd., Tokyo, p 7 (in Japanese) Council for Promotion of Countermeasures against Diabetes (Japan Medical Association, Japan Diabetes Society, Japan Association for Diabetes Education and Care) (2017) Essentials of Diabetes Treatment 2017, Bunkodo Co., Ltd., Tokyo, p 7 (in Japanese)
Metadata
Title
A large-scale observational study to investigate the current status of diabetic complications and their prevention in Japan (JDCP study 6): baseline dental and oral findings
Authors
Koji Inagaki
Takeshi Kikuchi
Toshihide Noguchi
Akio Mitani
Keiko Naruse
Tatsuaki Matsubara
Masamitsu Kawanami
Jun Negishi
Yasushi Furuichi
Eiji Nemoto
Satoru Yamada
Hiromasa Yoshie
Koichi Tabeta
Sachiyo Tomita
Atsushi Saito
Sayaka Katagiri
Yuichi Izumi
Hiroshi Nitta
Takanori Iwata
Yukihiro Numabe
Matsuo Yamamoto
Nobuo Yoshinari
Tsuyoshi Fujita
Hidemi Kurihara
Fusanori Nishimura
Toshihiko Nagata
Hiromichi Yumoto
Toru Naito
Kazuyuki Noguchi
Koichi Ito
Shinya Murakami
Rimei Nishimura
Naoko Tajima
Publication date
01-01-2021
Publisher
Springer Singapore
Published in
Diabetology International / Issue 1/2021
Print ISSN: 2190-1678
Electronic ISSN: 2190-1686
DOI
https://doi.org/10.1007/s13340-020-00465-3

Other articles of this Issue 1/2021

Diabetology International 1/2021 Go to the issue