Skip to main content
Key Specialties
Cardiology Diabetology Endocrinology Gastroenterology Geriatrics and Gerontology Gynecology and Obstetrics Hematology Infectious Disease Internal Medicine Nephrology Neurology Oncology Pediatrics Respiratory Medicine Rheumatology Surgery
Congress Coverage
2024 ACC Congress 2023 ESMO Congress 2023 EASD Congress 2023 ERS Congress 2023 ESC Congress 2023 EHA Congress 2023 ASCO Annual Meeting
Clinical Collections
Advances in Alzheimer’s

At a glance: The ONWARDS insulin icodec trials

A round-up of the ONWARDS phase 3 clinical trials evaluating the novel weekly insulin icodec in people with diabetes.
ADVANCED SEARCH
Log in
Top
Diabetology International
Published in: Diabetology International 2/2013

01-06-2013 | Case Report

Fulminant type 1 diabetes after allogeneic bone marrow transplantation for follicular lymphoma

Published in: Diabetology International | Issue 2/2013

Login to get access

Abstract

A 61-year-old man with refractory follicular lymphoma was treated with allogeneic bone marrow transplantation in July 2010. On day 121 after transplantation, when he was receiving cyclosporine and prednisolone as a treatment for graft-versus-host disease, he displayed a poor appetite and epigastralgia. Due to his elevated serum amylase and C-reactive protein levels, he was re-admitted on day 123 after transplantation. His course was complicated by fulminant type 1 diabetes on day 133, which required intensive insulin therapy. In addition, cytomegalovirus reactivation was observed at the onset of fulminant type 1 diabetes. In this case, both the donor and recipient displayed the following human leukocyte antigen haplotype: DRB1 (0101, 0901), DQB1 (0303, 0501). This is the first case report of fulminant type 1 diabetes after allogeneic hematopoietic stem cell transplantation.
Literature
1.
Imagawa A, Hanafusa T. Fulminant type 1 diabetes mellitus. Rinsho Byori. 2010;58:216–23 (in Japanese).PubMed
2.
Imagawa A, Hanafusa T, et al. A novel subtype of type 1 diabetes mellitus characterized by a rapid onset and an absence of diabetes-related antibodies. N Engl J Med. 2000;342(5):301–7.PubMedCrossRef
3.
Hanafusa T, Imagawa A. Fulminant type 1 diabetes: a novel clinical entity requiring special attention by all medical practitioners. Nat Clin Pract Endocrinol Metab. 2007;3(1):36–45.PubMedCrossRef
4.
Imagawa A, Hanafusa T, et al. Different contribution of class II HLA in fulminant and typical autoimmune type 1 diabetes mellitus. Diabetologia. 2005;48:294–300.PubMedCrossRef
5.
Kawabata Y, Ikegami H, et al. Asian-specific HLA haplotypes reveal heterogeneity of the contribution of HLA-DR and -DQ haplotypes to susceptibility to type 1 diabetes. Diabetes. 2002;51:545–51.PubMedCrossRef
6.
Jung TS, Chung SI, et al. A Korean patient with fulminant autoantibody-negative type 1 diabetes. Diabetes Care. 2004;27(12):3023–4.PubMedCrossRef
7.
Imagawa A, Hanafusa T, et al. High titres of IgA antibodies to enterovirus in fulminant type-1 diabetes. Diabetologia. 2005;48:290–3.PubMedCrossRef
8.
Shibasaki S, Imagawa A, et al. Expression of toll-like receptors in the pancreas of recent-onset fulminant type 1 diabetes. Endocr J. 2010;57(3):211–9.PubMedCrossRef
9.
Hanafusa T, Imagawa A, et al. Report of the Japan Diabetes Society’s Committee on research on fulminant type 1 diabetes mellitus: analysis of antiviral antibodies at disease onset. J Jpn Diabetes Soc. 2008;51(6):531–6. (in Japanese).
10.
Ohta M, Miura J, et al. A case of fulminant type 1 diabetes mellitus undergoing immunosuppression therapy after kidney transplantation with cytomegalovirus antigenemia elevation. J Jpn Diabetes Soc. 2009;52(11):919–25. (in Japanese).
11.
Nagaoka T, Terada M, et al. Insulin-dependent diabetes mellitus following acute pancreatitis caused by herpes simplex virus; a case report. J Jpn Diabetes Soc. 2001;44(4):335–40. (in Japanese).
12.
The Committee of Japan Diabetes Society on the diagnostic criteria of diabetes mellitus. Report of the Committee on the classification and diagnostic criteria of diabetes mellitus. J Jpn Diabetes Soc. 2010;53(6):450–67.
Metadata
Title
Fulminant type 1 diabetes after allogeneic bone marrow transplantation for follicular lymphoma
Publication date
01-06-2013
Published in
Diabetology International / Issue 2/2013
Print ISSN: 2190-1678
Electronic ISSN: 2190-1686
DOI
https://doi.org/10.1007/s13340-013-0106-2

Other articles of this Issue 2/2013

Diabetology International 2/2013 Go to the issue

Original Article

Correlation between weight loss and improvement of diabetes mellitus among obese type 2 diabetic patients

Original article

Association between diabetes and hearing impairment in a large health check-up population

Original Article

Mitochondria toxicity of antihyperlipidemic agents bezafibrate and fenofibrate

Editorial

Diagnostic criteria of diabetes

Commentary

FSP27 is a potent player regulating lipid storage in liver as well as adipose tissue

Report of the committee

Report of the JDS/JCA Joint Committee on Diabetes and Cancer

ACC 2024 Congress Coverage

Heart Failure Video

Year in Review: Heart failure and cardiomyopathies

Watch now

Watch this official video from ACC.24. Dr. Biykem Bozkurt discuss last year's major advances in heart failure and cardiomyopathies.

Semaglutide benefits people with type 2 diabetes and obesity-related heart failure

16-04-2024 Type 2 Diabetes News

Incentivised to exercise

11-04-2024 Lifestyle Modifications News

New intervention for STEMI-related cardiogenic shock

10-04-2024 Myocardial Infarction News

» View more highlights on the ACC 2024 congress hub page

Image Credits