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Autoimmunity Highlights
Published in: Autoimmunity Highlights 3/2015

Open Access 01-12-2015 | Case Report

Typical evanescent and atypical persistent polymorphic cutaneous rash in an adult Brazilian with Still’s disease: a case report and review of the literature

Authors: Despina Michailidou, Junghee Shin, Inga Forde, Kavitha Gopalratnam, Paul Cohen, Angela DeGirolamo

Published in: Autoimmunity Highlights | Issue 3/2015

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Abstract

Adult onset Still’s disease (AOSD) is a systemic auto-inflammatory condition of unknown etiology, characterized by high fever, an evanescent, salmon-pink maculopapular skin rash, arthralgia or arthritis and leukocytosis. AOSD can also present with atypical cutaneous manifestations, such as persistent pruritic coalescent papules or plaques and linear lesions that have highly distinctive pathological features and are usually associated with severe disease. Herein, we present a 31-year-old Brazilian man with both typical Still’s rash and atypical persistent polymorphic cutaneous manifestations associated with severe systemic inflammatory response syndrome. Eosinophils that are consistently lacking in the AOSD-associated skin lesions were evident in the skin biopsy of the persistent atypical cutaneous manifestations and were either drug-related or AOSD-associated.
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Metadata
Title
Typical evanescent and atypical persistent polymorphic cutaneous rash in an adult Brazilian with Still’s disease: a case report and review of the literature
Authors
Despina Michailidou
Junghee Shin
Inga Forde
Kavitha Gopalratnam
Paul Cohen
Angela DeGirolamo
Publication date
01-12-2015
Publisher
Springer International Publishing
Published in
Autoimmunity Highlights / Issue 3/2015
Print ISSN: 2038-0305
Electronic ISSN: 2038-3274
DOI
https://doi.org/10.1007/s13317-015-0071-9
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