Skip to main content
Top
Published in: Updates in Surgery 3/2020

01-09-2020 | Original Article

Italian multi-society modified Delphi consensus on the definition and management of anastomotic leakage in colorectal surgery

Authors: Antonino Spinelli, Gabriele Anania, Alberto Arezzo, Stefano Berti, Francesco Bianco, Paolo Pietro Bianchi, Maurizio De Giuli, Paola De Nardi, Paolo de Paolis, Caterina Foppa, Mario Guerrieri, Pierluigi Marini, Roberto Persiani, Diego Piazza, Gilberto Poggioli, Salvatore Pucciarelli, Domenico D’Ugo, Adolfo Renzi, Francesco Selvaggi, Gianfranco Silecchia, Marco Montorsi

Published in: Updates in Surgery | Issue 3/2020

Login to get access

Abstract

Introduction

The incidence of anastomotic leak (AL) has not decreased over the past decades and some important grey areas remain in its definition, prevention, and management. The aim of this study was to reach a national consensus on the definition of AL and to identify key points to be applied in clinical practice.

Methods

A 3-step modified Delphi method was used to establish consensus. Ten representative members of the major Italian surgical scientific societies with proven colorectal expertise were selected after a call to action. After a comprehensive literature search, each expert drew a list of evidence-based statements which were voted in round one by the scientific board. Panel members were asked to mark “totally disagree”, “partially agree” or “totally agree” for each statement and provide comments. The same voting method was used for round 2. Round 3 consisted of a final face-to-face meeting.

Results

Thirty-three statements (clustered into 14 topics) were included in round 1. Following the third voting round, a final list of 16 items was formulated, which encompass the following 9 topics: AL definition, patient- and operative-related risk factors, prevention measures, bowel preparation, surgical technique, intraoperative assessment, early diagnosis, radiological diagnosis and management of specific patterns of AL. The overall response rate was 100% for all items in all the three rounds.

Conclusions

This Delphi survey identified items that expert colorectal surgeons agreed were important to be applied in the prevention, diagnosis, and management of AL. This represents the first consensus involving all relevant national scientific societies, defining important and shared concepts in the diagnosis and management of AL.
Appendix
Available only for authorised users
Literature
1.
go back to reference Basilico V, Griffa B, Radaelli F et al (2014) Anastomotic leakage following colorectal resection for cancer: how to define, manage and treat it. Minerva Chir 69:245–252PubMed Basilico V, Griffa B, Radaelli F et al (2014) Anastomotic leakage following colorectal resection for cancer: how to define, manage and treat it. Minerva Chir 69:245–252PubMed
8.
go back to reference Peel AL, Taylor EW (1991) Proposed definitions for the audit of postoperative infection: a discussion paper. Surgical Infection Study Group. Ann R Coll Surg Engl 73:385–388PubMedPubMedCentral Peel AL, Taylor EW (1991) Proposed definitions for the audit of postoperative infection: a discussion paper. Surgical Infection Study Group. Ann R Coll Surg Engl 73:385–388PubMedPubMedCentral
19.
go back to reference Murphy MK, Black NA, Lamping DL et al (1998) Consensus development methods, and their use in clinical guideline development. Health Technol Assess 2:1–88 Murphy MK, Black NA, Lamping DL et al (1998) Consensus development methods, and their use in clinical guideline development. Health Technol Assess 2:1–88
23.
go back to reference Oxman AD, Sackett DL, Guyatt GH (1993) Users’ guides to the medical literature. I. How to get started. The Evidence-Based Medicine Working Group. JAMA 270:2093–2095PubMedCrossRef Oxman AD, Sackett DL, Guyatt GH (1993) Users’ guides to the medical literature. I. How to get started. The Evidence-Based Medicine Working Group. JAMA 270:2093–2095PubMedCrossRef
31.
go back to reference Chambrier C, Sztark F, Société Francophone de nutrition clinique et métabolisme (SFNEP), Société française d’anesthésie et réanimation (SFAR) (2012) French clinical guidelines on perioperative nutrition. Update of the 1994 consensus conference on perioperative artificial nutrition for elective surgery in adults. J Visc Surg 149:e325–336. https://doi.org/10.1016/j.jviscsurg.2012.06.006PubMedCrossRef Chambrier C, Sztark F, Société Francophone de nutrition clinique et métabolisme (SFNEP), Société française d’anesthésie et réanimation (SFAR) (2012) French clinical guidelines on perioperative nutrition. Update of the 1994 consensus conference on perioperative artificial nutrition for elective surgery in adults. J Visc Surg 149:e325–336. https://​doi.​org/​10.​1016/​j.​jviscsurg.​2012.​06.​006PubMedCrossRef
32.
50.
57.
go back to reference Mangano A, Gheza F, Chen LL et al (2018) Indocyanine Green (Icg)-enhanced fluorescence for intraoperative assessment of bowel microperfusion during laparoscopic and robotic colorectal surgery: the quest for evidence-based results. Surg Technol Int 32:101–104PubMed Mangano A, Gheza F, Chen LL et al (2018) Indocyanine Green (Icg)-enhanced fluorescence for intraoperative assessment of bowel microperfusion during laparoscopic and robotic colorectal surgery: the quest for evidence-based results. Surg Technol Int 32:101–104PubMed
68.
go back to reference den Dulk M, Witvliet MJ, Kortram K et al (2013) The DULK (Dutch leakage) and modified DULK score compared: actively seek the leak. Colorectal Dis 15:e528–533 den Dulk M, Witvliet MJ, Kortram K et al (2013) The DULK (Dutch leakage) and modified DULK score compared: actively seek the leak. Colorectal Dis 15:e528–533
69.
go back to reference Italian ColoRectal Anastomotic Leakage (iCral) Study Group (2020) Anastomotic leakage after elective colorectal surgery: a prospective multicentre observational study on use of the Dutch leakage score, serum procalcitonin and serum C-reactive protein for diagnosis. BJS Open. https://doi.org/10.1002/bjs5.50269CrossRef Italian ColoRectal Anastomotic Leakage (iCral) Study Group (2020) Anastomotic leakage after elective colorectal surgery: a prospective multicentre observational study on use of the Dutch leakage score, serum procalcitonin and serum C-reactive protein for diagnosis. BJS Open. https://​doi.​org/​10.​1002/​bjs5.​50269CrossRef
83.
go back to reference Adams SJ (2001) Projecting the next decade in safety management: a Delphi technique study. Prof Saf 46:26–29 Adams SJ (2001) Projecting the next decade in safety management: a Delphi technique study. Prof Saf 46:26–29
84.
go back to reference Hsu C-C, Sandford BA (2007) The Delphi technique: making sense of consensus. Pract Asses Res Eval 12:9 Hsu C-C, Sandford BA (2007) The Delphi technique: making sense of consensus. Pract Asses Res Eval 12:9
85.
go back to reference Walker AM, Selfe J (1996) The Delphi method: a useful tool for the allied health researcher. Int J Ther Rehab 3:677–681CrossRef Walker AM, Selfe J (1996) The Delphi method: a useful tool for the allied health researcher. Int J Ther Rehab 3:677–681CrossRef
87.
go back to reference Jones IW, Hooker RS (2011) Physician assistants in Canada: update on health policy initiatives. Can Fam Phys 57:e83–88 Jones IW, Hooker RS (2011) Physician assistants in Canada: update on health policy initiatives. Can Fam Phys 57:e83–88
Metadata
Title
Italian multi-society modified Delphi consensus on the definition and management of anastomotic leakage in colorectal surgery
Authors
Antonino Spinelli
Gabriele Anania
Alberto Arezzo
Stefano Berti
Francesco Bianco
Paolo Pietro Bianchi
Maurizio De Giuli
Paola De Nardi
Paolo de Paolis
Caterina Foppa
Mario Guerrieri
Pierluigi Marini
Roberto Persiani
Diego Piazza
Gilberto Poggioli
Salvatore Pucciarelli
Domenico D’Ugo
Adolfo Renzi
Francesco Selvaggi
Gianfranco Silecchia
Marco Montorsi
Publication date
01-09-2020
Publisher
Springer International Publishing
Published in
Updates in Surgery / Issue 3/2020
Print ISSN: 2038-131X
Electronic ISSN: 2038-3312
DOI
https://doi.org/10.1007/s13304-020-00837-z

Other articles of this Issue 3/2020

Updates in Surgery 3/2020 Go to the issue