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Published in: Insights into Imaging 3/2017

Open Access 01-06-2017 | Pictorial Review

Radiological imaging of teratological fetuses: what can we learn?

Authors: Lucas L. Boer, A. N. Schepens-Franke, J. J. A. van Asten, D. G. H. Bosboom, K. Kamphuis-van Ulzen, T. L. Kozicz, D. J. Ruiter, R-J. Oostra, W. M. Klein

Published in: Insights into Imaging | Issue 3/2017

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Abstract

Objectives

To determine the advantages of radiological imaging of a collection of full-term teratological fetuses in order to increase their scientific and educational value.

Background

Anatomical museums around the world exhibit full-term teratological fetuses. Unfortunately, these museums are regularly considered as “morbid cabinets”. Detailed dysmorphological information concerning the exhibited specimens is often lacking. Moreover, fetuses with severe and complex congenital anomalies are frequently diagnosed incompletely, incorrectly or not at all.

Methods

In order to verify diagnoses and to enrich their educational and scientific value, we imaged 41 out of the 72 teratological specimens present in the collection of our Anatomy and Pathology Museum in Nijmegen (The Netherlands) by means of magnetic resonance imaging (MRI) and computed tomography (CT). Additionally, contemporary dysmorphological insights and 3D models are implemented in the teratology education of medical students and residents.

Conclusions

Full-term teratological fetuses have become increasingly rare and deserve a prominent place in every anatomical museum; they are suitable for contemporary teratological research and education. Modern radiological techniques markedly enhance their scientific and didactic value.

Teaching Points

To explore the scientific and educational potential of institutionalised teratological collections
To understand the additional value of radiological imaging in diagnosing teratological specimens
To learn about the specific settings of MRI parameters when scanning fixed specimens
To recognise specific internal dysmorphology in several congenital anomalies
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Metadata
Title
Radiological imaging of teratological fetuses: what can we learn?
Authors
Lucas L. Boer
A. N. Schepens-Franke
J. J. A. van Asten
D. G. H. Bosboom
K. Kamphuis-van Ulzen
T. L. Kozicz
D. J. Ruiter
R-J. Oostra
W. M. Klein
Publication date
01-06-2017
Publisher
Springer Berlin Heidelberg
Published in
Insights into Imaging / Issue 3/2017
Electronic ISSN: 1869-4101
DOI
https://doi.org/10.1007/s13244-017-0551-8

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