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Indian Journal of Surgical Oncology
Published in: Indian Journal of Surgical Oncology 1/2023

11-08-2022 | Lymphoma | Original Article

A Retrospective Cohort Study of Gastrosplenic Fistula Secondary to Malignant Etiology: Single-Centre Experience of 5 Cases

Authors: Poras Chaudhary, Utsav Bhadana, Subhash Chandran, Achint Agarwal, Neeti Kapur

Published in: Indian Journal of Surgical Oncology | Issue 1/2023

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Abstract

Gastrosplenic fistula is an uncommon manifestation of malignancy of the stomach and spleen. The aim of this study is to present our 10-year experience on gastrosplenic fistula secondary to malignant etiology. Endoscopy, imaging, and histopathology records of all the patients with gastric and splenic malignant pathologies were reviewed retrospectively. The protocol was approved by the ethical review board of the institute. Descriptive statistics were used to summarize the data. A total of 5 cases were found to have gastrosplenic fistula. Of these 5 cases, 2 were due to large B cell lymphoma of the spleen, 1 was secondary to Hodgkin’s lymphoma of the stomach, 1 case was due to diffuse large B cell non-Hodgkin’s lymphoma of the stomach, and 1 patient was secondary to gastric adenocarcinoma. Gastrosplenic fistula is an exceptionally rare complication of gastrointestinal malignancy. Lymphoma of the spleen is the commonest cause while gastric adenocarcinoma causing gastrosplenic fistula is extremely rare. Most cases occur spontaneously.
Literature
1.
Rothermel LD, Chadwick CL, Thambi-Pillai T (2010) Gastrosplenic fistula: etiologies, diagnostic studies, and surgical management. Int Surg 95:270–272PubMed
2.
Garcia MA, Bernardos GL, Vaquero RA, MenchénViso L, Turégano FF (2009) Spontaneous gastrosplenic fistula secondary to primary gastric lymphoma. Rev Esp Enferm Dig 101:76–78
3.
4.
Bird MA, Amjadi D, Behrns KE (2002) Primary splenic lymphoma complicated by hematemesis and gastric erosion. South Med J 95:941–942CrossRefPubMed
5.
deScoville A, Bovy P, Demeester P (1967) Radiologic aerosplenomegaly caused by necrotizing splenic lymphosarcoma with double fistulization into the digestive tract. Acta Gastro-Enterol Belg 30:841–847
6.
Jain V, Pauli E, Sharzehi K, Moyer M (2011) Spontaneous gastrosplenic fistula secondary to diffuse large B-cell lymphoma. Gastrointest Endosc 73:608–609CrossRefPubMed
7.
Moran M, Bilgiç I, Dizen H, Dilektaşlı E, Köseoğlu T, Özmen M (2011) Spontaneous gastrosplenic fistula resulting from primary gastric lymphoma: case report and review of the literature. Balkan Med J 28:205–8
8.
Pizzirusso F, Gillet JP, Fobe D (2004) Isolated spleen metastatic involvement from a colorectal adenocarcinoma complicated with a gastrosplenic fistula A case report and literature review. Acta Chir Belg. 104:214–6CrossRefPubMed
9.
10.
Carolin KA, Prakash SH, Silva YJ (1997) Gastrosplenic fistulas: a case report and review of the literature. Am Surg 63:1007–1010PubMed
11.
Bubenik O, Lopez MJ, Greco AO, Kraybill WG, Cherwitz DL (1983) Gastrosplenic fistula following successful chemotherapy for disseminated histiocytic lymphoma. Cancer 52(994):6
12.
Kerem M, Sakrak O, Yilmaz TU, Gultekin FA, Dursun A, Bedirli A (2006) Spontaneous gastrosplenic fistula in primary gastric lymphoma: surgical management. Asian J Surg 29:287–290CrossRefPubMed
13.
Choi JE, Chung HJ, Lee HG (2002) Spontaneous gastrosplenic fistula: a rare complication of splenic diffuse large cell lymphoma. Abdom Imaging 27:728–730CrossRefPubMed
14.
David M, Mahvi and Seth B. Krantz (2012) Stomach. In Textbook of surgery, The biological basis of modern surgical practice. 19th edition. Edited by Courtney M. Townsend, R. Daniel Beauchamp, B. Mark Evers, Kenneth L. Mattox.Philadelphia: Saunders Elsevier; 1182–1226
15.
Seib CD, Rocha FG, Hwang DG, Shoji BT (2009) Gastrosplenic fistula from Hodgkin’s lymphoma. J Clin Oncol 10:27
16.
17.
18.
Aribaş BK, Başkan E, Altinyollar H, Ungül U, Cengız A, Erdıl HF (2008) Gastrosplenic fistula due to splenic large cell lymphoma diagnosed by percutaneous drainage before surgical treatment. Turk J Gastroenterol 19:69–70PubMed
19.
Cary ER, Tremaine WJ, Banks PM, Nagorney DM (1989) Isolated Crohn’s disease of the stomach. Mayo Clin Proc 64:776–779CrossRefPubMed
20.
Abrams JA, Wang TC (2010) From Adenocarcinoma and other tumours of the stomach. In Gastrointestinal and liver disease: pathophysiology/ diagnosis/management. Volume 1. 9th edition. Edited by Mark Feldman, Lawrence S. Friedman, Lawrence J Brandt. Philadelphia: Saunders Elsevier; 887–906
21.
Aviles A, Nambo MJ, Neri N et al (2004) Intensive chemotherapy in the treatment of aggressive diffuse large B-cell lymphoma: malignant lymphoma. Med Oncol 21:269–272CrossRefPubMed
22.
Hiltunen KM, Airo I, Mattila J, Helve O (1991) Massively bleeding gastrosplenic fistula following cytostatic chemotherapy of a malignant lymphoma. J Clin Gastroenterol 13:478–481CrossRefPubMed
23.
Moghazy KM (2008) Gastrosplenic fistula following chemotherapy for lymphoma. Gulf J Oncolog 3:64–67
24.
Al-Ashgar HI, Khan MQ, Ghamdi AM, Bamehriz FY, Maghfoor I (2007) Gastrosplenic fistula in Hodgkin’s lymphoma treated successfully by laparoscopic surgery and chemotherapy. Saudi Med J 28:1898–1900PubMed
Metadata
Title
A Retrospective Cohort Study of Gastrosplenic Fistula Secondary to Malignant Etiology: Single-Centre Experience of 5 Cases
Authors
Poras Chaudhary
Utsav Bhadana
Subhash Chandran
Achint Agarwal
Neeti Kapur
Publication date
11-08-2022
Publisher
Springer India
Published in
Indian Journal of Surgical Oncology / Issue 1/2023
Print ISSN: 0975-7651
Electronic ISSN: 0976-6952
DOI
https://doi.org/10.1007/s13193-022-01615-6

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