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Published in: Indian Journal of Gastroenterology 6/2012

01-12-2012 | Editorial

Inflammatory bowel disease: the Indian augury

Authors: Vineet Ahuja, Rakesh K Tandon

Published in: Indian Journal of Gastroenterology | Issue 6/2012

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Excerpt

A little boy accompanied by his father was taken to a museum of diseases. His father gloated upon mankind’s successes in alleviating diseases. The first window showed smallpox and its demise, the second window showed plague and its extermination, and the third window showed malaria and its systematic decimation. The little boy’s faith in dominance of medical science soared and he started getting convinced in the infallibility of man as he mounted the steps to the second floor of the museum. The second floor was damp and squidgy and so became the little boy’s enthusiasm when he saw conquests being replaced by new scourges, a whole row of emerging diseases: diabetes, multiple sclerosis, and celiac disease. Spontaneously, he remarked, “The disease wagon appears to have a mind of its own and keeps on replacing conquered diseases with a new or complex one. As if the disease wagon is leading medical scientists on an ever ongoing merry-go-round. Is the field of medicine moving in circles and trying to catch its own tail?” His father, a wise seasoned soul, assuaged his crestfallen son and explained “Predicting and controlling diseases ultimately requires an intuitive appreciation of biocomplexity—the elaborate interrelationships between biological systems (including human social systems) and their physical environments and until we do it the circle will move on.” This is precisely the most significant message the emergence of inflammatory bowel disease (IBD) in India augurs for the medical community. The initiative of Indian Society of Gastroenterology (ISG) Task Force and the ensuing survey is a laudatory effort which has propelled awareness of IBD as a disease from background to the fore. …
Literature
2.
go back to reference Bach J-F. The effect of infections on susceptibility to autoimmune and allergic diseases. N Engl J Med. 2002;347:911–20.PubMedCrossRef Bach J-F. The effect of infections on susceptibility to autoimmune and allergic diseases. N Engl J Med. 2002;347:911–20.PubMedCrossRef
3.
go back to reference Pugazhendhi S, Sahu MK, Subramanian V, Pulimood A, Ramakrishna BS. Environmental factors associated with Crohn’s disease in India. Indian J Gastroenterol. 2011;30:264–9.PubMedCrossRef Pugazhendhi S, Sahu MK, Subramanian V, Pulimood A, Ramakrishna BS. Environmental factors associated with Crohn’s disease in India. Indian J Gastroenterol. 2011;30:264–9.PubMedCrossRef
5.
go back to reference Schultz M, Butt AG. Is the north to south gradient in inflammatory bowel disease a global phenomenon? Expert Rev Gastroenterol Hepatol. 2012;6:445–7.PubMedCrossRef Schultz M, Butt AG. Is the north to south gradient in inflammatory bowel disease a global phenomenon? Expert Rev Gastroenterol Hepatol. 2012;6:445–7.PubMedCrossRef
6.
go back to reference Shivananda S, Lennard-Jones J, Logan R, et al. Incidence of inflammatory bowel disease across Europe: is there a difference between north and south? Results of the European Collaborative Study on Inflammatory Bowel Disease (EC-IBD). Gut. 1996;39:690–7.PubMedCrossRef Shivananda S, Lennard-Jones J, Logan R, et al. Incidence of inflammatory bowel disease across Europe: is there a difference between north and south? Results of the European Collaborative Study on Inflammatory Bowel Disease (EC-IBD). Gut. 1996;39:690–7.PubMedCrossRef
7.
go back to reference Khalili H, Huang ES, Ananthakrishnan AN, et al. Geographical variation and incidence of inflammatory bowel disease among US women. Gut. 2012. doi:10.1136/gutjnl-2011-301574. Epub ahead of print. Khalili H, Huang ES, Ananthakrishnan AN, et al. Geographical variation and incidence of inflammatory bowel disease among US women. Gut. 2012. doi:10.​1136/​gutjnl-2011-301574. Epub ahead of print.
8.
go back to reference Nerich V, Jantchou P, Boutron-Ruault MC, et al. Low exposure to sunlight is a risk factor for Crohn’s disease. Aliment Pharmacol Ther. 2011;33:940–5.PubMedCrossRef Nerich V, Jantchou P, Boutron-Ruault MC, et al. Low exposure to sunlight is a risk factor for Crohn’s disease. Aliment Pharmacol Ther. 2011;33:940–5.PubMedCrossRef
9.
go back to reference Ahuja V, Tandon RK. Inflammatory bowel disease in the Asia-Pacific area; a comparison with developed countries and regional differences. J Dig Dis. 2010;11:134–47.PubMedCrossRef Ahuja V, Tandon RK. Inflammatory bowel disease in the Asia-Pacific area; a comparison with developed countries and regional differences. J Dig Dis. 2010;11:134–47.PubMedCrossRef
10.
go back to reference Chouraki V, Savoye G, Dauchet L, et al. The changing pattern of Crohn’s disease incidence in northern France: a continuing increase in the 10- to 19-year-old age bracket (1988–2007). Aliment Pharmacol Ther. 2011;33:1133–42.PubMedCrossRef Chouraki V, Savoye G, Dauchet L, et al. The changing pattern of Crohn’s disease incidence in northern France: a continuing increase in the 10- to 19-year-old age bracket (1988–2007). Aliment Pharmacol Ther. 2011;33:1133–42.PubMedCrossRef
11.
go back to reference Latour P, Louis E, Belaiche J. Incidence of inflammatory bowel disease in the area of Liege: a 3 years prospective study (1993–1996). Acta Gastroenterol Belg. 1998;61:410–3.PubMed Latour P, Louis E, Belaiche J. Incidence of inflammatory bowel disease in the area of Liege: a 3 years prospective study (1993–1996). Acta Gastroenterol Belg. 1998;61:410–3.PubMed
12.
go back to reference Hellers G. Crohn’s disease in Stockholm county 1955–74. A study of epidemiology, result of surgical treatments and long term prognosis. Scand J Gastroenterol. 1979;7:401–5. Hellers G. Crohn’s disease in Stockholm county 1955–74. A study of epidemiology, result of surgical treatments and long term prognosis. Scand J Gastroenterol. 1979;7:401–5.
13.
go back to reference Bernstein CN, Blanchard JF, Rawsthorne P, et al. Epidemiology of Crohn’s disease and UC in a central Canadian province: a population-based study. Am J Epidemiol. 1999;149:916–24.PubMedCrossRef Bernstein CN, Blanchard JF, Rawsthorne P, et al. Epidemiology of Crohn’s disease and UC in a central Canadian province: a population-based study. Am J Epidemiol. 1999;149:916–24.PubMedCrossRef
14.
go back to reference Stowe SP, Redmond SR, Stormont JM, et al. An epidemiologic study of inflammatory bowel disease in Rochester, New York. Hospital incidence. Gastroenterology. 1990;98:104–10.PubMed Stowe SP, Redmond SR, Stormont JM, et al. An epidemiologic study of inflammatory bowel disease in Rochester, New York. Hospital incidence. Gastroenterology. 1990;98:104–10.PubMed
15.
go back to reference Thomas GA, Millar-Jones D, Rhodes J, et al. Incidence of Crohn’s disease in Cardiff over 60 years: 1986–1990 an update. Eur J Gastroenterol Hepatol. 1995;7:401–5.PubMed Thomas GA, Millar-Jones D, Rhodes J, et al. Incidence of Crohn’s disease in Cardiff over 60 years: 1986–1990 an update. Eur J Gastroenterol Hepatol. 1995;7:401–5.PubMed
16.
go back to reference Daiss W, Scheurlen M, Malchow H. Epidemiology of inflammatory bowel disease in the county of Tubingen (West Germany). Scand J Gastroenterol. 1989;24 suppl 170:39.CrossRef Daiss W, Scheurlen M, Malchow H. Epidemiology of inflammatory bowel disease in the county of Tubingen (West Germany). Scand J Gastroenterol. 1989;24 suppl 170:39.CrossRef
17.
go back to reference Molinié F, Gower-Rousseau C, Yzet T, et al. Opposite evolution in incidence of Crohn’s disease and ulcerative colitis in Northern France (1988–1999). Gut. 2004;53:843–8.PubMedCrossRef Molinié F, Gower-Rousseau C, Yzet T, et al. Opposite evolution in incidence of Crohn’s disease and ulcerative colitis in Northern France (1988–1999). Gut. 2004;53:843–8.PubMedCrossRef
18.
go back to reference Rogler G, Bernstein CN, Sood A, et al. Role of biological therapy for inflammatory bowel disease in developing countries. Gut. 2012;61:706–12.PubMedCrossRef Rogler G, Bernstein CN, Sood A, et al. Role of biological therapy for inflammatory bowel disease in developing countries. Gut. 2012;61:706–12.PubMedCrossRef
Metadata
Title
Inflammatory bowel disease: the Indian augury
Authors
Vineet Ahuja
Rakesh K Tandon
Publication date
01-12-2012
Publisher
Springer-Verlag
Published in
Indian Journal of Gastroenterology / Issue 6/2012
Print ISSN: 0254-8860
Electronic ISSN: 0975-0711
DOI
https://doi.org/10.1007/s12664-012-0272-3

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