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Published in: Canadian Journal of Anesthesia/Journal canadien d'anesthésie 11/2011

01-11-2011 | Reports of Original Investigations

More hypotension in patients taking antihypertensives preoperatively during shoulder surgery in the beach chair position

Authors: Terrence L. Trentman, MD, Sharon L. Fassett, CRNA, Justin K. Thomas, MD, Brie N. Noble, BS, Kevin J. Renfree, MD, Steven J. Hattrup, MD

Published in: Canadian Journal of Anesthesia/Journal canadien d'anesthésie | Issue 11/2011

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Abstract

Purpose

Hypotension is common in patients undergoing surgery in the sitting position under general anesthesia, and the risk may be exacerbated by the use of antihypertensive drugs taken preoperatively. The purpose of this study was to compare hypotensive episodes in patients taking antihypertensive medications with normotensive patients during shoulder surgery in the beach chair position.

Methods

Medical records of all patients undergoing shoulder arthroscopy during a 44-month period were reviewed retrospectively. The primary endpoint was the number of moderate hypotensive episodes (systolic blood pressure ≤ 85 mmHg) during the intraoperative period. Secondary endpoints included the frequency of vasopressor administration, total dose of vasopressors, and fluid administered. Values are expressed as mean (standard deviation).

Results

Of 384 patients who underwent shoulder surgery, 185 patients were taking no antihypertensive medication, and 199 were on at least one antihypertensive drug. The antihypertensive medication group had more intraoperative hypotensive episodes [1.7 (2.2) vs 1.2 (1.8); P = 0.01] and vasopressor administrations. Total dose of vasopressors and volume of fluids administered were similar between groups. The timing of the administration of angiotensin-converting enzyme inhibitors and of angiotensin receptor antagonists (≤ 10 hr vs > 10 hr before surgery) had no impact on intraoperative hypotension.

Conclusions

Preoperative use of antihypertensive medication was associated with an increased incidence of intraoperative hypotension. Compared with normotensive patients, patients taking antihypertensive drugs preoperatively are expected to require vasopressors more often to maintain normal blood pressure.
Footnotes
1
Lanier W. Cerebral perfusion pressure: err on the side of caution. APSF Newsletter 2009; 24: 1-4.
 
2
Munis J. The problems of posture, pressure, and perfusion: cerebral perfusion pressure defined. APSF Newsletter 2008; 22: 82-3.
 
3
Lee L, Caplan R. APSF workshop: cerebral perfusion experts share views on managment of head-up cases. APSF Newsletter 2010; 24: 45-8.
 
Literature
1.
go back to reference Pohl A, Cullen DJ. Cerebral ischemia during shoulder surgery in the upright position: a case series. J Clin Anesth 2005; 17: 463-9.PubMedCrossRef Pohl A, Cullen DJ. Cerebral ischemia during shoulder surgery in the upright position: a case series. J Clin Anesth 2005; 17: 463-9.PubMedCrossRef
2.
go back to reference Bhatti MT, Enneking FK. Visual loss and ophthalmoplegia after shoulder surgery. Anesth Analg 2003; 96: 899-902.PubMedCrossRef Bhatti MT, Enneking FK. Visual loss and ophthalmoplegia after shoulder surgery. Anesth Analg 2003; 96: 899-902.PubMedCrossRef
3.
go back to reference Murphy GS, Szokol JW, Marymont JH, et al. Cerebral oxygen desaturation events assessed by near-infrared spectroscopy during shoulder arthroscopy in the beach chair and lateral decubitus positions. Anesth Analg 2010; 111: 496-505.PubMedCrossRef Murphy GS, Szokol JW, Marymont JH, et al. Cerebral oxygen desaturation events assessed by near-infrared spectroscopy during shoulder arthroscopy in the beach chair and lateral decubitus positions. Anesth Analg 2010; 111: 496-505.PubMedCrossRef
4.
go back to reference Brabant SM, Bertrand M, Eyraud D, Darmon PL, Coriat P. The hemodynamic effects of anesthetic induction in vascular surgical patients chronically treated with angiotensin II receptor antagonists. Anesth Analg 1999; 89: 1388-92.PubMed Brabant SM, Bertrand M, Eyraud D, Darmon PL, Coriat P. The hemodynamic effects of anesthetic induction in vascular surgical patients chronically treated with angiotensin II receptor antagonists. Anesth Analg 1999; 89: 1388-92.PubMed
5.
go back to reference Brabant SM, Eyraud D, Bertrand M, Coriat P. Refractory hypotension after induction of anesthesia in a patient chronically treated with angiotensin receptor antagonists. Anesth Analg 1999; 89: 887-8.PubMed Brabant SM, Eyraud D, Bertrand M, Coriat P. Refractory hypotension after induction of anesthesia in a patient chronically treated with angiotensin receptor antagonists. Anesth Analg 1999; 89: 887-8.PubMed
6.
go back to reference Colson P, Saussine M, Seguin JR, Cuchet D, Chaptal PA, Roquefeuil B. Hemodynamic effects of anesthesia in patients chronically treated with angiotensin-converting enzyme inhibitors. Anesth Analg 1992; 74: 805-8.PubMed Colson P, Saussine M, Seguin JR, Cuchet D, Chaptal PA, Roquefeuil B. Hemodynamic effects of anesthesia in patients chronically treated with angiotensin-converting enzyme inhibitors. Anesth Analg 1992; 74: 805-8.PubMed
7.
go back to reference Comfere T, Sprung J, Kumar MM, et al. Angiotensin system inhibitors in a general surgical population. Anesth Analg 2005; 100: 636-44.PubMedCrossRef Comfere T, Sprung J, Kumar MM, et al. Angiotensin system inhibitors in a general surgical population. Anesth Analg 2005; 100: 636-44.PubMedCrossRef
8.
go back to reference Kheterpal S, Khodaparast O, Shanks A, O’Reilly M, Tremper KK. Chronic angiotensin-converting enzyme inhibitor or angiotensin receptor blocker therapy combined with diuretic therapy is associated with increased episodes of hypotension in noncardiac surgery. J Cardiothorac Vasc Anesth 2008; 22: 180-6.PubMedCrossRef Kheterpal S, Khodaparast O, Shanks A, O’Reilly M, Tremper KK. Chronic angiotensin-converting enzyme inhibitor or angiotensin receptor blocker therapy combined with diuretic therapy is associated with increased episodes of hypotension in noncardiac surgery. J Cardiothorac Vasc Anesth 2008; 22: 180-6.PubMedCrossRef
9.
go back to reference Rosenman DJ, McDonald FS, Ebbert JO, Erwin PJ, LaBella M, Montori VM. Clinical consequences of withholding versus administering renin-angiotensin-aldosterone system antagonists in the preoperative period. J Hosp Med 2008; 3: 319-25.PubMedCrossRef Rosenman DJ, McDonald FS, Ebbert JO, Erwin PJ, LaBella M, Montori VM. Clinical consequences of withholding versus administering renin-angiotensin-aldosterone system antagonists in the preoperative period. J Hosp Med 2008; 3: 319-25.PubMedCrossRef
10.
go back to reference Kapoor K, Singh B, Dewan LI. Variations in the configuration of the circle of Willis. Anat Sci Int 2008; 83: 96-106.PubMedCrossRef Kapoor K, Singh B, Dewan LI. Variations in the configuration of the circle of Willis. Anat Sci Int 2008; 83: 96-106.PubMedCrossRef
Metadata
Title
More hypotension in patients taking antihypertensives preoperatively during shoulder surgery in the beach chair position
Authors
Terrence L. Trentman, MD
Sharon L. Fassett, CRNA
Justin K. Thomas, MD
Brie N. Noble, BS
Kevin J. Renfree, MD
Steven J. Hattrup, MD
Publication date
01-11-2011
Publisher
Springer-Verlag
Published in
Canadian Journal of Anesthesia/Journal canadien d'anesthésie / Issue 11/2011
Print ISSN: 0832-610X
Electronic ISSN: 1496-8975
DOI
https://doi.org/10.1007/s12630-011-9575-6

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