Skip to main content
Top
Published in: Canadian Journal of Anesthesia/Journal canadien d'anesthésie 8/2009

Open Access 01-08-2009 | Reports of Original Investigations

Bilateral infraorbital nerve blocks decrease postoperative pain but do not reduce time to discharge following outpatient nasal surgery

Authors: Edward R. Mariano, MD, Deborah Watson, MD, Vanessa J. Loland, MD, Larry F. Chu, MD, Gloria S. Cheng, MD, Sachin H. Mehta, MD, Rosalita C. Maldonado, BS, Brian M. Ilfeld, MD

Published in: Canadian Journal of Anesthesia/Journal canadien d'anesthésie | Issue 8/2009

Login to get access

Abstract

Purpose

While infraorbital nerve blocks have demonstrated analgesic benefits for pediatric nasal and facial plastic surgery, no studies to date have explored the effect of this regional anesthetic technique on adult postoperative recovery. We designed this study to test the hypothesis that infraorbital nerve blocks combined with a standardized general anesthetic decrease the duration of recovery following outpatient nasal surgery.

Methods

At a tertiary care university hospital, healthy adult subjects scheduled for outpatient nasal surgery were randomly assigned to receive bilateral infraorbital injections with either 0.5% bupivacaine (Group IOB) or normal saline (Group NS) using an intraoral technique immediately following induction of general anesthesia. All subjects underwent a standardized general anesthetic regimen and were transported to the recovery room following tracheal extubation. The primary outcome was the duration of recovery (minutes) from recovery room admission until actual discharge to home. Secondary outcomes included average and worst pain scores, nausea and vomiting, and supplemental opioid requirements.

Results

Forty patients were enrolled. A statistically significant difference in mean [SD] recovery room duration was not observed between Groups IOB and NS (131 [61] min vs 133 [58] min, respectively; P = 0.77). Subjects in Group IOB did experience a reduction in average pain on a 0–100 mm scale (mean [95% confidence interval]) compared to Group NS (−11 [−21 to 0], P = 0.047), but no other comparison of secondary outcomes was statistically significant.

Conclusions

When added to a standardized general anesthetic, bilateral IOB do not decrease actual time to discharge following outpatient nasal surgery despite a beneficial effect on postoperative pain.
Literature
1.
go back to reference Prabhu KP, Wig J, Grewal S. Bilateral infraorbital nerve block is superior to peri-incisional infiltration for analgesia after repair of cleft lip. Scand J Plast Reconstr Surg Hand Surg 1999; 33: 83–7.PubMedCrossRef Prabhu KP, Wig J, Grewal S. Bilateral infraorbital nerve block is superior to peri-incisional infiltration for analgesia after repair of cleft lip. Scand J Plast Reconstr Surg Hand Surg 1999; 33: 83–7.PubMedCrossRef
2.
go back to reference Nicodemus HF, Ferrer MJ, Cristobal VC, de Castro L. Bilateral infraorbital block with 0.5% bupivacaine as post-operative analgesia following cheiloplasty in children. Scand J Plast Reconstr Surg Hand Surg 1991; 25: 253–7.PubMedCrossRef Nicodemus HF, Ferrer MJ, Cristobal VC, de Castro L. Bilateral infraorbital block with 0.5% bupivacaine as post-operative analgesia following cheiloplasty in children. Scand J Plast Reconstr Surg Hand Surg 1991; 25: 253–7.PubMedCrossRef
3.
go back to reference Bosenberg AT, Kimble FW. Infraorbital nerve block in neonates for cleft lip repair: anatomical study and clinical application. Br J Anaesth 1995; 74: 506–8.PubMedCrossRef Bosenberg AT, Kimble FW. Infraorbital nerve block in neonates for cleft lip repair: anatomical study and clinical application. Br J Anaesth 1995; 74: 506–8.PubMedCrossRef
4.
go back to reference McAdam D, Muro K, Suresh S. The use of infraorbital nerve block for postoperative pain control after transsphenoidal hypophysectomy. Reg Anesth Pain Med 2005; 30: 572–3.PubMed McAdam D, Muro K, Suresh S. The use of infraorbital nerve block for postoperative pain control after transsphenoidal hypophysectomy. Reg Anesth Pain Med 2005; 30: 572–3.PubMed
5.
go back to reference Rajamani A, Kamat V, Rajavel VP, Murthy J, Hussain SA. A comparison of bilateral infraorbital nerve block with intravenous fentanyl for analgesia following cleft lip repair in children. Paediatr Anaesth 2007; 17: 133–9.PubMedCrossRef Rajamani A, Kamat V, Rajavel VP, Murthy J, Hussain SA. A comparison of bilateral infraorbital nerve block with intravenous fentanyl for analgesia following cleft lip repair in children. Paediatr Anaesth 2007; 17: 133–9.PubMedCrossRef
6.
go back to reference Molliex S, Navez M, Baylot D, Prades JM, Elkhoury Z, Auboyer C. Regional anaesthesia for outpatient nasal surgery. Br J Anaesth 1996; 76: 151–3.PubMed Molliex S, Navez M, Baylot D, Prades JM, Elkhoury Z, Auboyer C. Regional anaesthesia for outpatient nasal surgery. Br J Anaesth 1996; 76: 151–3.PubMed
7.
go back to reference Higashizawa T, Koga Y. Effect of infraorbital nerve block under general anesthesia on consumption of isoflurane and postoperative pain in endoscopic endonasal maxillary sinus surgery. J Anesth 2001; 15: 136–8.PubMedCrossRef Higashizawa T, Koga Y. Effect of infraorbital nerve block under general anesthesia on consumption of isoflurane and postoperative pain in endoscopic endonasal maxillary sinus surgery. J Anesth 2001; 15: 136–8.PubMedCrossRef
8.
go back to reference Chung F, Mezei G. Factors contributing to a prolonged stay after ambulatory surgery. Anesth Analg 1999; 89: 1352–9.PubMedCrossRef Chung F, Mezei G. Factors contributing to a prolonged stay after ambulatory surgery. Anesth Analg 1999; 89: 1352–9.PubMedCrossRef
9.
go back to reference Macario A, Weinger M, Carney S, Kim A. Which clinical anesthesia outcomes are important to avoid? The perspective of patients. Anesth Analg 1999; 89: 652–8.PubMedCrossRef Macario A, Weinger M, Carney S, Kim A. Which clinical anesthesia outcomes are important to avoid? The perspective of patients. Anesth Analg 1999; 89: 652–8.PubMedCrossRef
10.
go back to reference Hadzic A, Arliss J, Kerimoglu B, et al. A comparison of infraclavicular nerve block versus general anesthesia for hand and wrist day-case surgeries. Anesthesiology 2004; 101: 127–32.PubMedCrossRef Hadzic A, Arliss J, Kerimoglu B, et al. A comparison of infraclavicular nerve block versus general anesthesia for hand and wrist day-case surgeries. Anesthesiology 2004; 101: 127–32.PubMedCrossRef
11.
go back to reference Hadzic A, Karaca PE, Hobeika P, et al. Peripheral nerve blocks result in superior recovery profile compared with general anesthesia in outpatient knee arthroscopy. Anesth Analg 2005; 100: 976–81.PubMedCrossRef Hadzic A, Karaca PE, Hobeika P, et al. Peripheral nerve blocks result in superior recovery profile compared with general anesthesia in outpatient knee arthroscopy. Anesth Analg 2005; 100: 976–81.PubMedCrossRef
12.
go back to reference Singelyn FJ, Lhotel L, Fabre B. Pain relief after arthroscopic shoulder surgery: a comparison of intraarticular analgesia, suprascapular nerve block, and interscalene brachial plexus block. Anesth Analg 2004; 99: 589–92.PubMedCrossRef Singelyn FJ, Lhotel L, Fabre B. Pain relief after arthroscopic shoulder surgery: a comparison of intraarticular analgesia, suprascapular nerve block, and interscalene brachial plexus block. Anesth Analg 2004; 99: 589–92.PubMedCrossRef
13.
go back to reference Lynch MT, Syverud SA, Schwab RA, Jenkins JM, Edlich R. Comparison of intraoral and percutaneous approaches for infraorbital nerve block. Acad Emerg Med 1994; 1: 514–9.PubMed Lynch MT, Syverud SA, Schwab RA, Jenkins JM, Edlich R. Comparison of intraoral and percutaneous approaches for infraorbital nerve block. Acad Emerg Med 1994; 1: 514–9.PubMed
14.
go back to reference Suresh S, Wheeler M. Practical pediatric regional anesthesia. Anesthesiol Clin North America 2002; 20: 83–113.PubMedCrossRef Suresh S, Wheeler M. Practical pediatric regional anesthesia. Anesthesiol Clin North America 2002; 20: 83–113.PubMedCrossRef
15.
go back to reference Gan TJ, Meyer T, Apfel CC, et al. Consensus guidelines for managing postoperative nausea and vomiting. Anesth Analg 2003; 97: 62–71.PubMedCrossRef Gan TJ, Meyer T, Apfel CC, et al. Consensus guidelines for managing postoperative nausea and vomiting. Anesth Analg 2003; 97: 62–71.PubMedCrossRef
16.
go back to reference Aldrete JA. Modifications to the postanesthesia score for use in ambulatory surgery. J Perianesth Nurs 1998; 13: 148–55.PubMedCrossRef Aldrete JA. Modifications to the postanesthesia score for use in ambulatory surgery. J Perianesth Nurs 1998; 13: 148–55.PubMedCrossRef
17.
go back to reference Viitanen H, Annila P, Viitanen M, Tarkkila P. Premedication with midazolam delays recovery after ambulatory sevoflurane anesthesia in children. Anesth Analg 1999; 89: 75–9.PubMedCrossRef Viitanen H, Annila P, Viitanen M, Tarkkila P. Premedication with midazolam delays recovery after ambulatory sevoflurane anesthesia in children. Anesth Analg 1999; 89: 75–9.PubMedCrossRef
18.
go back to reference Bodian CA, Freedman G, Hossain S, Eisenkraft JB, Beilin Y. The visual analog scale for pain: clinical significance in postoperative patients. Anesthesiology 2001; 95: 1356–61.PubMedCrossRef Bodian CA, Freedman G, Hossain S, Eisenkraft JB, Beilin Y. The visual analog scale for pain: clinical significance in postoperative patients. Anesthesiology 2001; 95: 1356–61.PubMedCrossRef
19.
go back to reference Jensen MP, Chen C, Brugger AM. Interpretation of visual analog scale ratings and change scores: a reanalysis of two clinical trials of postoperative pain. J Pain 2003; 4: 407–14.PubMedCrossRef Jensen MP, Chen C, Brugger AM. Interpretation of visual analog scale ratings and change scores: a reanalysis of two clinical trials of postoperative pain. J Pain 2003; 4: 407–14.PubMedCrossRef
20.
go back to reference Korttila KT, Jokinen JD. Timing of administration of dolasetron affects dose necessary to prevent postoperative nausea and vomiting. J Clin Anesth 2004; 16: 364–70.PubMedCrossRef Korttila KT, Jokinen JD. Timing of administration of dolasetron affects dose necessary to prevent postoperative nausea and vomiting. J Clin Anesth 2004; 16: 364–70.PubMedCrossRef
21.
go back to reference Farrar JT, Young JP Jr, LaMoreaux L, Werth JL, Poole RM. Clinical importance of changes in chronic pain intensity measured on an 11-point numerical pain rating scale. Pain 2001; 94: 149–58.PubMedCrossRef Farrar JT, Young JP Jr, LaMoreaux L, Werth JL, Poole RM. Clinical importance of changes in chronic pain intensity measured on an 11-point numerical pain rating scale. Pain 2001; 94: 149–58.PubMedCrossRef
22.
go back to reference Pavlin DJ, Chen C, Penaloza DA, Polissar NL, Buckley FP. Pain as a factor complicating recovery and discharge after ambulatory surgery. Anesth Analg 2002; 95: 627–34.PubMedCrossRef Pavlin DJ, Chen C, Penaloza DA, Polissar NL, Buckley FP. Pain as a factor complicating recovery and discharge after ambulatory surgery. Anesth Analg 2002; 95: 627–34.PubMedCrossRef
23.
go back to reference Edler AA, Mariano ER, Golianu B, Kuan C, Pentcheva K. An analysis of factors influencing postanesthesia recovery after pediatric ambulatory tonsillectomy and adenoidectomy. Anesth Analg 2007; 104: 784–9.PubMedCrossRef Edler AA, Mariano ER, Golianu B, Kuan C, Pentcheva K. An analysis of factors influencing postanesthesia recovery after pediatric ambulatory tonsillectomy and adenoidectomy. Anesth Analg 2007; 104: 784–9.PubMedCrossRef
24.
go back to reference Liu SS, Strodtbeck WM, Richman JM, Wu CL. A comparison of regional versus general anesthesia for ambulatory anesthesia: a meta-analysis of randomized controlled trials. Anesth Analg 2005; 101: 1634–42.PubMedCrossRef Liu SS, Strodtbeck WM, Richman JM, Wu CL. A comparison of regional versus general anesthesia for ambulatory anesthesia: a meta-analysis of randomized controlled trials. Anesth Analg 2005; 101: 1634–42.PubMedCrossRef
25.
go back to reference Shirakami G, Teratani Y, Namba T, Hirakata H, Tazuke-Nishimura M. Delayed discharge and acceptability of ambulatory surgery in adult outpatients receiving general anesthesia. J Anesth 2005; 19: 93–101.PubMedCrossRef Shirakami G, Teratani Y, Namba T, Hirakata H, Tazuke-Nishimura M. Delayed discharge and acceptability of ambulatory surgery in adult outpatients receiving general anesthesia. J Anesth 2005; 19: 93–101.PubMedCrossRef
26.
go back to reference Seago JA, Weitz S, Walczak S. Factors influencing stay in the postanesthesia care unit: a prospective analysis. J Clin Anesth 1998; 10: 579–87.PubMedCrossRef Seago JA, Weitz S, Walczak S. Factors influencing stay in the postanesthesia care unit: a prospective analysis. J Clin Anesth 1998; 10: 579–87.PubMedCrossRef
27.
go back to reference Williams BA, Kentor ML, Vogt MT, et al. Economics of nerve block pain management after anterior cruciate ligament reconstruction: potential hospital cost savings via associated postanesthesia care unit bypass and same-day discharge. Anesthesiology 2004; 100: 697–706.PubMedCrossRef Williams BA, Kentor ML, Vogt MT, et al. Economics of nerve block pain management after anterior cruciate ligament reconstruction: potential hospital cost savings via associated postanesthesia care unit bypass and same-day discharge. Anesthesiology 2004; 100: 697–706.PubMedCrossRef
28.
go back to reference Williams BA, Kentor ML, Williams JP, et al. PACU bypass after outpatient knee surgery is associated with fewer unplanned hospital admissions but more phase II nursing interventions. Anesthesiology 2002; 97: 981–8.PubMedCrossRef Williams BA, Kentor ML, Williams JP, et al. PACU bypass after outpatient knee surgery is associated with fewer unplanned hospital admissions but more phase II nursing interventions. Anesthesiology 2002; 97: 981–8.PubMedCrossRef
29.
go back to reference Recart A, Issioui T, White PF, et al. The efficacy of celecoxib premedication on postoperative pain and recovery times after ambulatory surgery: a dose-ranging study. Anesth Analg 2003; 96: 1631–5.PubMed Recart A, Issioui T, White PF, et al. The efficacy of celecoxib premedication on postoperative pain and recovery times after ambulatory surgery: a dose-ranging study. Anesth Analg 2003; 96: 1631–5.PubMed
30.
go back to reference Issioui T, Klein KW, White PF, et al. The efficacy of premedication with celecoxib and acetaminophen in preventing pain after otolaryngologic surgery. Anesth Analg 2002; 94: 1188–93.PubMedCrossRef Issioui T, Klein KW, White PF, et al. The efficacy of premedication with celecoxib and acetaminophen in preventing pain after otolaryngologic surgery. Anesth Analg 2002; 94: 1188–93.PubMedCrossRef
31.
go back to reference Demiraran Y, Ozturk O, Guclu E, Iskender A, Ergin MH, Tokmak A. Vasoconstriction and analgesic efficacy of locally infiltrated levobupivacaine for nasal surgery. Anesth Analg 2008; 106: 1008–11.PubMedCrossRef Demiraran Y, Ozturk O, Guclu E, Iskender A, Ergin MH, Tokmak A. Vasoconstriction and analgesic efficacy of locally infiltrated levobupivacaine for nasal surgery. Anesth Analg 2008; 106: 1008–11.PubMedCrossRef
Metadata
Title
Bilateral infraorbital nerve blocks decrease postoperative pain but do not reduce time to discharge following outpatient nasal surgery
Authors
Edward R. Mariano, MD
Deborah Watson, MD
Vanessa J. Loland, MD
Larry F. Chu, MD
Gloria S. Cheng, MD
Sachin H. Mehta, MD
Rosalita C. Maldonado, BS
Brian M. Ilfeld, MD
Publication date
01-08-2009
Publisher
Springer-Verlag
Published in
Canadian Journal of Anesthesia/Journal canadien d'anesthésie / Issue 8/2009
Print ISSN: 0832-610X
Electronic ISSN: 1496-8975
DOI
https://doi.org/10.1007/s12630-009-9119-5

Other articles of this Issue 8/2009

Canadian Journal of Anesthesia/Journal canadien d'anesthésie 8/2009 Go to the issue