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The journal of nutrition, health & aging
Published in: The journal of nutrition, health & aging 10/2020

Open Access 01-12-2020

Age-Related Frailty: A Clinical Model for Geroscience?

Authors: Catherine Takeda, D. Angioni, E. Setphan, T. Macaron, P. De Souto Barreto, S. Sourdet, F. Sierra, B. Vellas

Published in: The journal of nutrition, health & aging | Issue 10/2020

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Abstract

In their everyday practice, geriatricians are confronted with the fact that older age and multimorbidity are associated to frailty. Indeed, if we take the example of a very old person with no diseases that progressively becomes frail with no other explanation, there is a natural temptation to link frailty to aging. On the other hand, when an old person with a medical history of diabetes, arthritis and congestive heart failure becomes frail there appears an obvious relationship between frailty and comorbidity. The unsolved question is: Considering that frailty is multifactorial and in the majority of cases comorbidity and aging are acting synergistically, can we disentangle the main contributor to the origin of frailty: disease or aging? We believe that it is important to be able to differentiate age-related frailty from frailty related to comorbidity. In fact, with the emergence of geroscience, the physiopathology, diagnosis, prognosis and treatment will probably have to be different in the future.
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Metadata
Title
Age-Related Frailty: A Clinical Model for Geroscience?
Authors
Catherine Takeda
D. Angioni
E. Setphan
T. Macaron
P. De Souto Barreto
S. Sourdet
F. Sierra
B. Vellas
Publication date
01-12-2020
Publisher
Springer Paris
Published in
The journal of nutrition, health & aging / Issue 10/2020
Print ISSN: 1279-7707
Electronic ISSN: 1760-4788
DOI
https://doi.org/10.1007/s12603-020-1491-4

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