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The journal of nutrition, health & aging

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01-04-2020 | Denture

Association Between Number of Teeth, Denture Use and Frailty: Findings from the West China Health and Aging Trend Study

Authors: Y. Zhang, M. Ge, W. Zhao, L. Hou, X. Xia, X. Liu, Z. Zuo, Y. Zhao, J. Yue, Birong Dong

Published in: The journal of nutrition, health & aging | Issue 4/2020

Abstract

Objective

Frailty and poor oral health are both common age-related conditions. However, the association between oral health and frailty has not been explored thoroughly among older Chinese adults. We aimed to investigate the associations between number of teeth, denture use, and frailty among older adults in western China.

Design

Cross-sectional study.

Setting

Community-based.

Participants

Participants were 4037 community-dwelling individuals aged 60 and older from the West China Health and Aging Trend (WCHAT) study.

Measurements

Frailty was assessed using the physical frailty phenotype (PFP) and categorized as non-frail, prefrail and frail. In addition, number of teeth and denture use were examined by calibrated dentists. Multinomial logistic regression models were performed to examine the association between number of teeth, denture use, and frailty.

Results

The overall prevalence of frailty was 6.7% among 4037 participants aged 60 and older in western China. Participants with no more than 20 teeth were associated with higher odds of being prefrail or frail whether wearing dentures or not. Denture using could not help lower the odds of being prefrail or frail for older adults with fewer teeth.

Conclusions

This study suggested that frailty was associated with having fewer teeth (≤20 teeth) among older Chinese adults. Future research involving targeted interventions addressing number of teeth may help provide information to establish effective strategies for frailty prevention in older adults.

Morley JE, Vellas B, van Kan GA, Anker SD, Bauer JM, Bernabei R, Cesari M, Chumlea WC, Doehner W, Evans J, Fried LP, Guralnik JM, Katz PR, Malmstrom TK, McCarter RJ, Gutierrez Robledo LM, Rockwood K, von Haehling S, Vandewoude MF, Walston J. Frailty Consensus: A Call to Action. Journal of the American Medical Directors Association 2013;14 (6):392–397. doi:https://doi.org/10.1016/j.jamda.2013.03.022 PubMedPubMedCentral

Xue QL. The frailty syndrome: definition and natural history. Clinics in geriatric medicine 2011;27 (1):1–15. doi:https://doi.org/10.1016/j.cger.2010.08.009 PubMedPubMedCentral

Bergman H, Ferrucci L, Guralnik J, Hogan DB, Hummel S, Karunananthan S, Wolfson C (2007) Frailty: an emerging research and clinical paradigm—issues and controversies. The journals of gerontology Series A, Biological sciences and medical sciences 2007;62 (7):731–737. doi:https://doi.org/10.1093/gerona/62.7.731 PubMedPubMedCentral

Wu C, Smit E, Xue QL, Odden MC. Prevalence and Correlates of Frailty Among Community-Dwelling Chinese Older Adults: The China Health and Retirement Longitudinal Study. The journals of gerontology Series A, Biological sciences and medical sciences 2017;73 (1): 102–108. doi:https://doi.org/10.1093/gerona/glx098 PubMedPubMedCentral

Fried LP, Tangen CM, Walston J, Newman AB, Hirsch C, Gottdiener J, Seeman T, Tracy R, Kop WJ, Burke G, McBurnie MA. Frailty in older adults: evidence for a phenotype. The journals of gerontology Series A, Biological sciences and medical sciences 2001;56 (3):M146–156. doi:https://doi.org/10.1093/gerona/56.3.ml46 PubMed

Wu C, Kim DH, Xue QL, Lee DSH, Varadhan R, Odden MC. Association of Frailty With Recovery From Disability Among Community-Dwelling Older Adults: Results From Two Large U.S. Cohorts. The journals of gerontology Series A, Biological sciences and medical sciences 2019;74 (4):575–581. doi:https://doi.org/10.1093/gerona/gly080 PubMed

Lee DH, Buth KJ, Martin BJ, Yip AM, Hirsch GM. Frail patients are at increased risk for mortality and prolonged institutional care after cardiac surgery. Circulation 2010;121 (8):973–978. doi:https://doi.org/10.1161/circulationaha.108.841437 PubMed

Cesari M, Prince M, Thiyagarajan JA, De Carvalho IA, Bernabei R, Chan P, Gutierrez-Robledo LM, Michel JP, Morley JE, Ong P, Rodriguez Manas L, Sinclair A, Won CW, Beard J, Vellas B. Frailty: An Emerging Public Health Priority. Journal of the American Medical Directors Association 2016;17 (3): 188–192. doi:https://doi.org/10.1016/j.jamda.2015.12.016 PubMed

Mello Ade C, Engstrom EM, Alves LC. Health-related and socio-demographic factors associated with frailty in the elderly: a systematic literature review. Cadernos de saude publica 2014;30 (6):1143–1168PubMed

10.

Artaza-Artabe I, Saez-Lopez P, Sanchez-Hernandez N, Fernandez-Gutierrez N, Malafarina V. The relationship between nutrition and frailty: Effects of protein intake, nutritional supplementation, vitamin D and exercise on muscle metabolism in the elderly. A systematic review. Maturitas 2016;93:89–99. doi:https://doi.org/10.1016/j.maturitas.2016.04.009 PubMed

11.

Soysal P, Stubbs B, Lucato P, Luchini C, Solmi M, Peluso R, Sergi G, Isik AT, Manzato E, Maggi S, Maggio M, Prina AM, Cosco TD, Wu YT, Veronese N. Inflammation and frailty in the elderly: A systematic review and meta-analysis. Ageing research reviews 2016;31:1–8. doi:https://doi.org/10.1016/j.arr.2016.08.006 PubMed

12.

Buigues C, Padilla-Sanchez C, Garrido JF, Navarro-Martinez R, Ruiz-Ros V, Cauli O. The relationship between depression and frailty syndrome: a systematic review. Aging & mental health 2015;19 (9):762–772. doi:https://doi.org/10.1080/13607863.2014.967174

13.

Hakeem FF, Bernabe E, Sabbah W. Association between oral health and frailty: A systematic review of longitudinal studies. Gerodontology 2019;36 (3):205–215. doi:https://doi.org/10.1111/ger.12406 PubMed

14.

Torres LH, Tellez M, Hilgert JB, Hugo FN, de Sousa MD, Ismail AI. Frailty, Frailty Components, and Oral Health: A Systematic Review. Journal of the American Geriatrics Society 2015;63 (12):2555–2562. doi:https://doi.org/10.1110/jgs.13826 PubMed

15.

Petersen PE, Yamamoto T. Improving the oral health of older people: the approach of the WHO Global Oral Health Programme. Community dentistry and oral epidemiology 2005;33 (2):81–92. doi:https://doi.org/10.1111/j.l600-0528.2004.00219.x PubMed

16.

Tanaka T, Takahashi K, Hirano H, Kikutani T, Watanabe Y, Ohara Y, Furuya H, Tsuji T, Akishita M, Iijima K. Oral Frailty as a Risk Factor for Physical Frailty and Mortality in Community-Dwelling Elderly. The journals of gerontology Series A, Biological sciences and medical sciences. 2017;doi:https://doi.org/10.1093/gerona/glx225

17.

de Andrade FB, Lebrao ML, Santos JL, Duarte YA. Relationship between oral health and frailty in community-dwelling elderly individuals in Brazil. Journal of the American Geriatrics Society 2013;61 (5):809–814. doi:https://doi.org/10.1111/jgs.12221 PubMed

18.

Castrejon-Perez RC, Jimenez-Corona A, Bernabe E, Villa-Romero AR, Arrive E, Dartigues JF, Gutierrez-Robledo LM, Borges-Yanez SA. Oral Disease and 3-Year Incidence of Frailty in Mexican Older Adults. The journals of gerontology Series A, Biological sciences and medical sciences 2017;72 (7):951–957. doi:https://doi.org/10.1093/gerona/glw201 PubMed

19.

Ramsay SE, Papachristou E, Watt RG, Tsakos G, Lennon LT, Papacosta AO, Moynihan P, Sayer AA, Whincup PH, Wannamethee SG. Influence of Poor Oral Health on Physical Frailty: A Population-Based Cohort Study of Older British Men. Journal of the American Geriatrics Society 2018;66 (3):473–479. doi:https://doi.org/10.1111/jgs.15175 PubMed

20.

Naka O, Anastassiadou V, Pissiotis A. Association between functional tooth units and chewing ability in older adults: a systematic review. Gerodontology 2014;31 (3): 166–177. doi:https://doi.org/10.1111/ger.12016 PubMed

21.

Sheiham A, Steele J. Does the condition of the mouth and teeth affect the ability to eat certain foods, nutrient and dietary intake and nutritional status amongst older people? Public Health Nutr 2001;4 (3):797–803PubMed

22.

Lee S, Sabbah W. Association between number of teeth, use of dentures and musculoskeletal frailty among older adults. Geriatrics & gerontology international 2018;18 (4):592–598. doi:https://doi.org/10.1111/ggi.13220

23.

Zhou BF. Predictive values of body mass index and waist circumference for risk factors of certain related diseases in Chinese adults-study on optimal cut-off points of body mass index and waist circumference in Chinese adults. Biomed Environ Sci 2002;15(1):83–96PubMed

24.

Yan-yan W, Chuan-yao D, Ding D, Yi S, Tai-ping L, Ji-rong Y, Ning G. Development and validation of the China Leisure Time Physical Activity Questionnaire in the elderly. Practical Geriatrics 2019;33 (03):229–233

25.

Taylor HL, Jacobs DR, Jr., Schucker B, Knudsen J, Leon AS, Debacker G. A questionnaire for the assessment of leisure time physical activities. J Chronic Dis 1978;31 (12):741–755. doi:https://doi.org/10.1016/0021-9681(78)90058-9 PubMed

26.

Steele JG, Treasure ET, O’Sullivan I, Morris J, Murray JJ. Adult Dental Health Survey 2009: transformations in British oral health 1968–2009. British dental journal 2012;213 (10):523–527. doi:https://doi.org/10.1038/sj.bdj.2012.1067 PubMed

27.

Sheiham A, Steele JG, Marcenes W, Finch S, Walls AW. The relationship between oral health status and Body Mass Index among older people: a national survey of older people in Great Britain. British dental journal 2002;192 (12):703–706. doi:https://doi.org/10.1038/sj.bdj.4801461 PubMed

28.

Mahoney FI, Barthel DW. Functional evaluation: the Barthel Index. Maryland St Med J 1965;14

29.

Yesavage JA, Brink TL, Rose TL, Lum O, Huang V, Adey M, Leirer VO. Development and validation of a geriatric depression screening scale: a preliminary report. J Psychiatr Res 1982;17 (1):37–49PubMed

30.

Fried LP, Ferrucci L, Darer J, Williamson JD, Anderson G. Untangling the concepts of disability, frailty, and comorbidity: implications for improved targeting and care. The journals of gerontology Series A, Biological sciences and medical sciences 2004;59 (3):255–263. doi: https://doi.org/10.1093/gerona/59.3.m255 PubMed

31.

Gu Y, Wu W, Bai J, Chen X, Chen X, Yu L, Zhang Q, Zou Z, Luo X, Pei X, Liu X, Tan X. Association between the number of teeth and frailty among Chinese older adults: a nationwide cross-sectional study. BMJ open 2019;9 (10):e029929. doi: https://doi.org/10.1136/bmjopen-2019-029929 PubMedPubMedCentral

32.

Clegg A, Young J, Iliffe S, Rikkert MO, Rockwood K. Frailty in elderly people. Lancet 2013;381 (9868):752–762. doi:https://doi.org/10.1016/s0140-6736(12)62167-9 PubMed

33.

Cigolle CT, Ofstedal MB, Tian Z, Blaum CS. Comparing models of frailty: the Health and Retirement Study. Journal of the American Geriatrics Society 2009;57 (5):830–839. doi:https://doi.org/10.1111/j.1532-5415.2009.02225.x PubMed

34.

Dupre ME, Gu D, Warner DF, Yi Z. Frailty and type of death among older adults in China: prospective cohort study. Bmj 2009;338:b1175. doi:https://doi.org/10.1136/bmj.b1175 PubMedPubMedCentral

35.

Semba RD, Blaum CS, Bartali B, Xue QL, Ricks MO, Guralnik JM, Fried LP. Denture use, malnutrition, frailty, and mortality among older women living in the community. The journal of nutrition, health & aging 2006;10 (2): 161–167

36.

Castrejon-Perez RC, Borges-Yanez SA. Frailty from an Oral Health Point of View. The Journal of frailty & aging 2014;3 (3):180–186. doi:https://doi.org/10.14283/jfa.2014.21

37.

Jain M, Kaira LS, Sikka G, Singh S, Gupta A, Sharma R, Sawla L, Mathur A. How do age and tooth loss affect oral health impacts and quality of life? A study comparing two state samples of gujarat and rajasthan. J Dent (Tehran) 2012;9 (2):135–144

38.

Linden GJ, McClean K, Young I, Evans A, Kee F. Persistently raised C-reactive protein levels are associated with advanced periodontal disease. Journal of clinical periodontology 2008;35 (9):741–747. doi:https://doi.org/10.1111/j.1600-051X.2008.01288.x PubMed

39.

Tsakos G, Watt RG, Rouxel PL, de Oliveira C, Demakakos P. Tooth loss associated with physical and cognitive decline in older adults. Journal of the American Geriatrics Society 2015;63 (1):91–99. doi: https://doi.org/10.1111/jgs.13190 PubMed

40.

Chen QL, Zeng XT, Luo ZX, Duan XL, Qin J, Leng WD. Tooth loss is associated with increased risk of esophageal cancer: evidence from a meta-analysis with dose-response analysis. Sci Rep 2016;6:18900. doi:https://doi.org/10.1038/srep18900 PubMedPubMedCentral

41.

Cheng F, Zhang M, Wang Q, Xu H, Dong X, Gao Z, Chen J, Wei Y, Qin F. Tooth loss and risk of cardiovascular disease and stroke: A dose-response meta analysis of prospective cohort studies. PloS one 2018;13 (3):e0194563. doi:https://doi.org/10.1371/journal.pone.0194563 PubMedPubMedCentral

42.

Petersen PE, Kandelman D, Arpin S, Ogawa H. Global oral health of older people-call for public health action. Community dental health 2010;27 (4 Suppl 2):257–267PubMed

43.

Bakker MH, Vissink A, Spoorenberg SLW, Jager-Wittenaar H, Wynia K, Visser A. Are Edentulousness, Oral Health Problems and Poor Health-Related Quality of Life Associated with Malnutrition in Community-Dwelling Elderly (Aged 75 Years and Over)? A Cross-Sectional Study. Nutrients 2018;10 (12). doi:https://doi.org/10.3390/nul0121965

44.

Kamdem B, Seematter-Bagnoud L, Botrugno F, Santos-Eggimann B. Relationship between oral health and Fried’s frailty criteria in community-dwelling older persons. BMC geriatrics 2017;17 (1):174. doi:https://doi.org/10.1186/sl2877-017-0568-3 PubMedPubMedCentral

45.

Wang H, Zhang L, Zou H-F. Regional disparity in health and health care in China. China Economics And Management Academy, Central University of Finance and Economics, 2012

Title: Association Between Number of Teeth, Denture Use and Frailty: Findings from the West China Health and Aging Trend Study
Authors: Y. Zhang
M. Ge
W. Zhao
L. Hou
X. Xia
X. Liu
Z. Zuo
Y. Zhao
J. Yue
Birong Dong
Publication date: 01-04-2020
Publisher: Springer Paris
Keyword: Denture
Published in: The journal of nutrition, health & aging / Issue 4/2020
Print ISSN: 1279-7707
Electronic ISSN: 1760-4788
DOI: https://doi.org/10.1007/s12603-020-1346-z

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Objective

Design

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Measurements

Results

Conclusions

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