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Published in: The journal of nutrition, health & aging 8/2019

01-08-2019 | Bisphosphonate

Spontaneous Insufficiency Fractures

Authors: M. Brennan, P. M. O’Shea, S. T. O’Keeffe, E. C. Mulkerrin

Published in: The journal of nutrition, health & aging | Issue 8/2019

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Abstract

Spontaneous insufficiency fractures are caused by normal or physiological stress on weakened bone. The leading cause of insufficiency fractures is osteoporosis which has a propensity to affect older patients. Other causes or associated factors are disorders which affect bone metabolism, collagen formation, bone remodelling and medications such as bisphosphonates and glucocorticoids. Pathological fractures and abuse are important causes of unexplained fractures which warrant careful consideration. Spontaneous fractures of the long bones affect on average 1% of nursing home residents per year and tend to occur in patients who are bed-bound with joint contractures. Preventative measures for spontaneous insufficiency fractures include optimising nutrition to include an adequate intake of protein, calcium and vitamin D, maintaining mobility and preventing long periods of bed-rest and treatment of underlying pre-disposing conditions.

Literature
  1. Fujiwara S. Importance of raising awareness elderly. Int. J. Clin. Rheumatol 2010;5(4):395–397View Article
  2. Viceconti M, Taddei F, Cristofolini L, Martelli S, Falcinelli C, & Schileo E. Are spontaneous fractures possible? An example of clinical application for personalised, multiscale neuro-musculo-skeletal modelling. Journal of biomechanics. 2012;45(3):421–426.View Article
  3. Donnelly E, Saleh A, Unnanuntana A, Lane JM. Atypical femoral fractures: epidemiology, etiology, and patient management. Current opinion in supportive and palliative care. 2012;6(3):348–354.View Article
  4. Marshall RA, Mandell JC, Weaver MJ, Ferrone M, Sodickson A, Khurana B. Imaging Features and Management of Stress, Atypical, and Pathologic Fractures. Radiographics: a review publication of the Radiological Society of North America, Inc. 2018;38(7): 2173–2192View Article
  5. Kazemian G H, Manafi Rasi A, Amoozadeh Omrani F, Yamrali A. Spontaneous Fractures or Physical Abuse?. J Orthop Spine Trauma. 2016;2(3):e4938.View Article
  6. Kane RS, Goodwin JS. Spontaneous fractures of the long bones in nursing home patients. Am J Med 1991;90: 263–266View Article
  7. Kane RS, Burns EA, Goodwin JS. Minimal trauma fractures in older nursing home residents. The interaction of functional status, trauma, and site of fracture. J Am Geriatr Soc. 1995;43:156–159.View Article
  8. Martin-Hunyadi C, Heitz D, Kaltenbach G et al. Spontaneous insufficiency fractures of long bones: a prospective epidemiological survey in nursing home subjects. Archives of gerontology and geriatrics. 2000;31(3): 207–214View Article
  9. Takamoto S, Saeki S, Yabumoto Y et al. Spontaneous fractures of long bones associated with joint contractures in bedridden elderly inpatients: clinical features and outcome. Journal of the American Geriatrics Society 2005;53(8): 1439–1441.View Article
  10. Takamoto S, Masuyama T, Nakajima M et al. Alterations of bone mineral density of the femurs in hemiplegia. Calicif Tissue Int 1995;56:259–262View Article
  11. Ha YC, Cho MR, Park KH, Kim SY, Koo KH. Is surgery necessary for femoral insufficiency fractures after long-term bisphosphonate therapy?. Clinical Orthopaedics and Related Research 2010;468(12): 3393–3398View Article
  12. Ing-Lorenzini K, Desmeules J, Plachta O, Suva D, Dayer P, Peter R. Low-energy femoral fractures associated with the long-term use of bisphosphonates. Drug Safety 2009;32(9): 775–785View Article
  13. Kanis JA, Johansson H, Oden A, Johnell O, De Laet C, Melton III LJ, Eisman JA. A meta-analysis of prior corticosteroid use and fracture risk. Journal of bone and mineral research 2004;19(6): 893–899View Article
  14. National Osteoporosis Guideline Group NOGG 2017: Clinical guideline for the prevention and treatment of osteoporosis
  15. Leblanc AD, Schneider VS, Evans HJ et al. Bone mineral loss and recovery after 17 weeks of bed rest. J. Bone Miner. Res. 1990;5:843–850View Article
  16. Appell HJ. Muscular atrophy following immobilization. A review. Sports Med. 1990;10:42–58View Article
  17. Conti F, Piscitelli P, Italiano G et al. Adherence to Calcium and Vitamin D supplementations: results from the ADVICE Survey. Clinical cases in mineral and bone metabolism. 2012;9(3):157.PubMedPubMed Central
  18. Cramer JA, Gold DT, Silverman SL, Lewiecki EM. A systematic review of persistence and compliance with bisphosphonates for osteoporosis. Osteoporosis International 2007;18(8): 1023–1031.View Article
  19. Morley JE, Abbatecola AM, Argiles JM et al. Sarcopenia with limited mobility: an international consensus. Journal of the American Medical Directors Association. 2011;12(6):403–9.View Article
  20. Landi F, Liperoti R, Fusco D et al. Prevalence and Risk Factors of Sarcopenia Among Nursing Home Older Residents, The Journals of Gerontology: 2012;A:67A(1): 48–55View Article
  21. Mitchell SL, Teno JM, Kiely DK et al. The clinical course of advanced dementia. New England Journal of Medicine. 2009;361(16):1529–38.View Article
Metadata
Title
Spontaneous Insufficiency Fractures
Authors
M. Brennan
P. M. O’Shea
S. T. O’Keeffe
E. C. Mulkerrin
Publication date
01-08-2019
Publisher
Springer Paris
Published in
The journal of nutrition, health & aging / Issue 8/2019
Print ISSN: 1279-7707
Electronic ISSN: 1760-4788
DOI
https://doi.org/10.1007/s12603-019-1234-6

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