Skip to main content
Top
Published in: The journal of nutrition, health & aging 7/2019

01-07-2019

Frailty Could Predict Death in Older Adults after Admission at Emergency Department? A 6-month Prospective Study from a Middle-Income Country

Authors: Ivan Aprahamian, G. V. Aricó de Almeida, C. F. de Vasconcellos Romanin, T. Gomes Caldas, N. T. Antunes Yoshitake, L. Bataglini, S. Mori Lin, A. Alves Pereira, L. Nara Alegrini Longhi, R. L. Mamoni, J. E. Martinelli

Published in: The journal of nutrition, health & aging | Issue 7/2019

Login to get access

Abstract

Background

The number of older adults attending emergency department (ED) is increasing all over the world. Usually, those patients are potentially more complex due to their greater number of comorbidities, cognitive disorders, and functional or physical disabilities. Frailty is a vulnerable state that could predict adverse outcomes of those patients. There are very few studies that addressed this topic in the ED, and none of them used a simple instrument for frailty assessment.

Objectives

The primary outcome was to evaluate the association between frailty identified through the FRAIL questionnaire at baseline and death after a 6-month follow-up period after hospital discharge from the ED. Secondary outcomes were readmission to the ED and disability after 6 months.

Methods

A 6-month follow-up prospective study (FASES study) was conducted at a university-based trauma-center ED in Jundiaí, southwestern of Brazil. A total of 316 older adults aged 60 or older were randomly included based on a lottery of their medical record admission number. Frailty was evaluated through the FRAIL questionnaire. The association between frailty and death was estimated through a binary logistic regression adjusted for age, sex, and cognitive performance.

Results

From the total sample, the mean age was 72.11±8.0 years, and 51.6% were women. Participants presented 2.28±1.4 comorbidities and 25.6% were frail. Mean hospital stay was 5.43±5.6 days. Death occurred in 52 participants, readmission to the emergency in 55, and new disability in 16 after 6 months. Frailty was associated with an odds ratio of 2.18 for death after 6 months (95% CI = 1.10–4.31; p = 0.024). This association lost significance after multivariate analysis taking into account cognitive performance. There was no association between frailty status at baseline and readmission to the ED or disability.

Conclusion

The identification of frailty using the FRAIL at admission was not predictive of death after a 6-month period after discharge from the ED. Simple frailty assessment could identify patients at higher risk for death in the follow-up.
Literature
6.
go back to reference Wilber ST, Gerson LW. Emergency department care. In: Halter JB, Ouslander JG, Tinetti ME, Studenski S, High KP, Asthana S, eds. Hazzard’s geriatric medicine and gerontology. 6th ed. New York: McGraw-Hill Professional; 2009: 221–228. Wilber ST, Gerson LW. Emergency department care. In: Halter JB, Ouslander JG, Tinetti ME, Studenski S, High KP, Asthana S, eds. Hazzard’s geriatric medicine and gerontology. 6th ed. New York: McGraw-Hill Professional; 2009: 221–228.
7.
go back to reference McNamara RM, Rousseau E, Sanders AB. Geriatric emergency medicine: a survey of practicing emergency physicians. Ann Emerg Med. 1992; 21: 796–801.CrossRefPubMed McNamara RM, Rousseau E, Sanders AB. Geriatric emergency medicine: a survey of practicing emergency physicians. Ann Emerg Med. 1992; 21: 796–801.CrossRefPubMed
8.
go back to reference McCusker J, Verdon J, Tousignant P, de Courval LP, Dendukuri N, Belzile E. Rapid emergency department intervention for older people reduces risk of functional decline: results of a multicenter randomized trial. J Am Geriatr Soc. 2001; 49: 1272–1281.CrossRefPubMed McCusker J, Verdon J, Tousignant P, de Courval LP, Dendukuri N, Belzile E. Rapid emergency department intervention for older people reduces risk of functional decline: results of a multicenter randomized trial. J Am Geriatr Soc. 2001; 49: 1272–1281.CrossRefPubMed
9.
go back to reference Carpenter CR, Platts-Mills TF. Evolving prehospital, emergency department, and “inpatient” management models for geriatric emergencies. Clin Geriatr Med. 2013; 29(1): 31–47.CrossRefPubMed Carpenter CR, Platts-Mills TF. Evolving prehospital, emergency department, and “inpatient” management models for geriatric emergencies. Clin Geriatr Med. 2013; 29(1): 31–47.CrossRefPubMed
10.
go back to reference Mion LC, Palmer RM, Anetzberger GJ, Meldon SW. Establishing a case-finding and referral system for at-risk older individuals in the emergency department setting: the SIGNET model. J Am Geriatr Soc. 2001; 49: 1379–1386.CrossRefPubMed Mion LC, Palmer RM, Anetzberger GJ, Meldon SW. Establishing a case-finding and referral system for at-risk older individuals in the emergency department setting: the SIGNET model. J Am Geriatr Soc. 2001; 49: 1379–1386.CrossRefPubMed
11.
go back to reference Caplan GA, Williams AJ, Daly B, Abraham K. A randomized, controlled trial of comprehensive geriatric assessment and multidisciplinary intervention after discharge of elderly from the emergency department - the DEED II study. J Am Geriatr Soc. 2004; 52: 1417–1423.CrossRefPubMed Caplan GA, Williams AJ, Daly B, Abraham K. A randomized, controlled trial of comprehensive geriatric assessment and multidisciplinary intervention after discharge of elderly from the emergency department - the DEED II study. J Am Geriatr Soc. 2004; 52: 1417–1423.CrossRefPubMed
12.
go back to reference Hustey FM, Mion LC, Connor JT, Emerman CL, Campbell J, Palmer RM. A brief risk stratification tool to predict functional de- cline in older adults discharged from emergency departments. J Am Geriatr Soc. 2007; 55: 1269–1274.CrossRefPubMed Hustey FM, Mion LC, Connor JT, Emerman CL, Campbell J, Palmer RM. A brief risk stratification tool to predict functional de- cline in older adults discharged from emergency departments. J Am Geriatr Soc. 2007; 55: 1269–1274.CrossRefPubMed
19.
go back to reference Almeida OP, Almeida SA. Confiabilidade da versão brasileira da Escala de Depressão em Geriatria (GDS) versão reduzida. Arq Neuro-Psiquiatr. 1999; 57:421–426.CrossRef Almeida OP, Almeida SA. Confiabilidade da versão brasileira da Escala de Depressão em Geriatria (GDS) versão reduzida. Arq Neuro-Psiquiatr. 1999; 57:421–426.CrossRef
20.
go back to reference Santos JG, Pereira JR, Teixeira CVL, Corazza DI, Vital TM, Costa JLR. Sintomas depressivos e prejuízo funcional de idosos de um Centro-Dia Geriátrico. J Bras de Psiquiatr. 2012; 61:2.CrossRef Santos JG, Pereira JR, Teixeira CVL, Corazza DI, Vital TM, Costa JLR. Sintomas depressivos e prejuízo funcional de idosos de um Centro-Dia Geriátrico. J Bras de Psiquiatr. 2012; 61:2.CrossRef
21.
go back to reference Apolinario D, Lichtenthaler DG, Magaldi RM, Soares AT, Busse AL, Amaral JR, et al. Using temporal orientation, category fluency, and word recall for detecting cognitive impairment: the 10-point cognitive screener (10-CS). Int J Geriatr Psychiatry. 2016; 31: 4–12. doi: https://doi.org/10.1002/gps.4282.CrossRefPubMed Apolinario D, Lichtenthaler DG, Magaldi RM, Soares AT, Busse AL, Amaral JR, et al. Using temporal orientation, category fluency, and word recall for detecting cognitive impairment: the 10-point cognitive screener (10-CS). Int J Geriatr Psychiatry. 2016; 31: 4–12. doi: https://​doi.​org/​10.​1002/​gps.​4282.CrossRefPubMed
22.
go back to reference Morley JE, Malmstrom TK, Miller DK. A simple frailty questionnaire (FRAIL) predicts outcomes in middle aged African Americans. J Nutr Health Aging. 2012; 16: 601–608.CrossRefPubMedPubMedCentral Morley JE, Malmstrom TK, Miller DK. A simple frailty questionnaire (FRAIL) predicts outcomes in middle aged African Americans. J Nutr Health Aging. 2012; 16: 601–608.CrossRefPubMedPubMedCentral
24.
go back to reference Salvi F, Morichi V, Grilli A, Lancioni L, Spazzafumo L, Polonara S, et al. Screening for frailty in elderly emergency department patients by using the Identification of Seniors At Risk (ISAR). J Nutr Health Aging. 2012; 16(4): 313–318.CrossRefPubMed Salvi F, Morichi V, Grilli A, Lancioni L, Spazzafumo L, Polonara S, et al. Screening for frailty in elderly emergency department patients by using the Identification of Seniors At Risk (ISAR). J Nutr Health Aging. 2012; 16(4): 313–318.CrossRefPubMed
25.
go back to reference Sirois MJ, Griffith L, Perry J, Daoust R, Veillette N, Lee J, et al. Measuring frailty can help emergency departments identify independent seniors at risk of functional decline after minor injuries. J Gerontol A Biol Sci Med Sci. 2015; 72(1):68–74.CrossRefPubMedPubMedCentral Sirois MJ, Griffith L, Perry J, Daoust R, Veillette N, Lee J, et al. Measuring frailty can help emergency departments identify independent seniors at risk of functional decline after minor injuries. J Gerontol A Biol Sci Med Sci. 2015; 72(1):68–74.CrossRefPubMedPubMedCentral
Metadata
Title
Frailty Could Predict Death in Older Adults after Admission at Emergency Department? A 6-month Prospective Study from a Middle-Income Country
Authors
Ivan Aprahamian
G. V. Aricó de Almeida
C. F. de Vasconcellos Romanin
T. Gomes Caldas
N. T. Antunes Yoshitake
L. Bataglini
S. Mori Lin
A. Alves Pereira
L. Nara Alegrini Longhi
R. L. Mamoni
J. E. Martinelli
Publication date
01-07-2019
Publisher
Springer Paris
Published in
The journal of nutrition, health & aging / Issue 7/2019
Print ISSN: 1279-7707
Electronic ISSN: 1760-4788
DOI
https://doi.org/10.1007/s12603-019-1207-9

Other articles of this Issue 7/2019

The journal of nutrition, health & aging 7/2019 Go to the issue