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Published in: The journal of nutrition, health & aging 10/2018

01-12-2018

Pre Frail 80: Multifactorial Intervention to Prevent Progression of Pre-Frailty to Frailty in the Elderly

Authors: L. Gené Huguet, M. Navarro González, B. Kostov, M. Ortega Carmona, C. Colungo Francia, M. Carpallo Nieto, A. Hervás Docón, R. Vilarrasa Sauquet, R. García Prado, A. Sisó-Almirall

Published in: The journal of nutrition, health & aging | Issue 10/2018

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Abstract

Objectives

Preventing or delaying frailty has important benefits in the elderly, and in health and social services. Studies have demonstrated the effectiveness of multifactorial interventions in the frail elderly, but there are fewer studies on community-dwelling pre-frail individuals. Identifying pre-frail individuals susceptible to intervention could prevent or delay frailty and its consequences and associated disability and might reverse the state from pre-frail to robust. To evaluate a multifactorial, interdisciplinary primary care intervention in community-dwelling pre-frail elderly patients aged ≥ 80 years.

Design

Randomized clinical trial in a Barcelona primary healthcare centre.

Setting

We included 200 community-dwelling subjects aged ≥ 80 years meeting the Fried pre-frailty criteria. Participants were randomized to intervention and control groups.

Intervention

The intervention group received a 6-month interdisciplinary intervention based on physical exercise, Mediterranean diet advice, assessment of inadequate prescribing in polypharmacy patients and social assessment, while the control group received standard primary healthcare treatment.

Results

173 pre-frail participants (86.5%) completed the study; mean age 84.5 years, 64.5% female. At twelve months, frailty was lower in the intervention group (RR 2.90; 95%CI 1.45 to 8.69). Reversion to robustness was greater in the intervention group (14.1% vs.1.1%, p <0.001). Functional and nutritional status, adherence to Mediterranean diet, quality of life, and functional mobility were improved in the intervention group (p ≤0.001).

Conclusion

A multifactorial, interdisciplinary primary healthcare intervention focused on physical exercise, nutrition, review of polypharmacy and social assessment prevented frailty in pre-frail elderly patients, and improved functional capacity, quality of life and adherence to the Mediterranean diet.
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Metadata
Title
Pre Frail 80: Multifactorial Intervention to Prevent Progression of Pre-Frailty to Frailty in the Elderly
Authors
L. Gené Huguet
M. Navarro González
B. Kostov
M. Ortega Carmona
C. Colungo Francia
M. Carpallo Nieto
A. Hervás Docón
R. Vilarrasa Sauquet
R. García Prado
A. Sisó-Almirall
Publication date
01-12-2018
Publisher
Springer Paris
Published in
The journal of nutrition, health & aging / Issue 10/2018
Print ISSN: 1279-7707
Electronic ISSN: 1760-4788
DOI
https://doi.org/10.1007/s12603-018-1089-2

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