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01-09-2015 | Case Report

Experience using denosumab for lung metastases of giant cell tumor of bone

Authors: Yuto Watanabe, Mitsunori Kaya, Mikito Sasaki, Masato Emori, Yasutaka Murahashi, Emi Mizushima, Tamotsu Souma, Shintaro Sugita, Tadashi Hasegawa, Toshihiko Yamashita

Published in: European Orthopaedics and Traumatology | Issue 3/2015

Abstract

The treatment of unresectable multiple lung metastasis of giant cell tumor of bone (GCTB) is challenging. In the current manuscript, we present a case who presented with multiple lung metastases of GCTB and was successfully managed with the use of denosumab allowing for surgical resection of the metastatic lesions that was previously deemed unresectable. Pathologic examination also clearly demonstrated the histological effects of denosumab. We emphasize on effective response to denosumab even in metastatic GCTB.

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Title: Experience using denosumab for lung metastases of giant cell tumor of bone
Authors: Yuto Watanabe
Mitsunori Kaya
Mikito Sasaki
Masato Emori
Yasutaka Murahashi
Emi Mizushima
Tamotsu Souma
Shintaro Sugita
Tadashi Hasegawa
Toshihiko Yamashita
Publication date: 01-09-2015
Publisher: Springer Berlin Heidelberg
Published in: European Orthopaedics and Traumatology / Issue 3/2015
Print ISSN: 1867-4569
Electronic ISSN: 1867-4577
DOI: https://doi.org/10.1007/s12570-015-0308-0

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Experience using denosumab for lung metastases of giant cell tumor of bone

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