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01-03-2014 | Case Report

A report of two patients with a history of pyoderma gangrenosum where total knee arthroplasty was performed under prophylactic immunosuppression

Authors: Daniel S. Hill, Soulat Naim, Andrew M. Watts, Marina Morgan, Chris Bower, Andrew D. Toms

Published in: European Orthopaedics and Traumatology | Issue 1/2014

Excerpt

Pyoderma gangrenosum (PG) is a rare relapsing autoimmune inflammatory disorder resulting in skin necrosis and ulceration. It can be idiopathic or associated with other conditions. Sterile pustular lesions can occur 24–48 h following cutaneous trauma in up to 30 % of patients with PG. Blobnet first described this process in 1937 that he termed pathergy [1]. …

Blobernm F (1937) Zur rezidiviereden Hypopyon-Iritis. Augenheilk 91:129–139

Hill DS, O'Neill JK, Toms AD, Watts AM (2011 Nov) Pyoderma gangrenosum: a report of a rare complication after knee arthroplasty requiring muscle flap cover supplemented by negative pressure therapy and hyperbaric oxygen. Journal of Plastic, Reconstructive, and Aesthetic Surgery 64(11):1528–1532

Mandal A, Addison P, Stewart K, Neligan P (2006) Vacuum-assisted closure therapy in pyoderma gangrenosum. Eur J Plast Surg 28:529–531CrossRef

Wadia F, Malik MH, Porter ML (2007) Post operative wound breakdown cause by pyoderma gangrenosum after bilateral simultaneous total knee arthroplasty. Journal of Arthoplasty 22(8):1232–1235CrossRef

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Craig FF, Thomas KS, Mitchell EJ, Williams HC, Norrie J, Mason, JM, Ormerod AD (2012) UK dermatology clinical trials Network's STOP GAP trial (a multicentre trial of prednisolone versus ciclosporin for pyoderma gangrenosum): protocol for a randomised controlled trial. Trials., 13. p. 51.

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Title: A report of two patients with a history of pyoderma gangrenosum where total knee arthroplasty was performed under prophylactic immunosuppression
Authors: Daniel S. Hill
Soulat Naim
Andrew M. Watts
Marina Morgan
Chris Bower
Andrew D. Toms
Publication date: 01-03-2014
Publisher: Springer Berlin Heidelberg
Published in: European Orthopaedics and Traumatology / Issue 1/2014
Print ISSN: 1867-4569
Electronic ISSN: 1867-4577
DOI: https://doi.org/10.1007/s12570-013-0195-1

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A report of two patients with a history of pyoderma gangrenosum where total knee arthroplasty was performed under prophylactic immunosuppression

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