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Netherlands Heart Journal
Published in: Netherlands Heart Journal 1/2021

Open Access 01-01-2021 | Editor’s Comment

Percutaneous coronary intervention for chronic total coronary occlusion: Do. Or do not. There is no try

Authors: P. Knaapen, J. P. Henriques, A. Nap, F. Arslan

Published in: Netherlands Heart Journal | Issue 1/2021

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Excerpt

Chronic total coronary occlusion (CTO) represents the final stage of coronary artery disease (CAD) and is documented in as many as one-fifth of patients. Traditionally, CTOs are treated differently than non-occlusive yet obstructive, i.e. ischaemia-inducing, CAD. Despite comparable symptoms and an identical albeit more advanced disease stage, patients with CTOs are less frequently offered percutaneous coronary intervention (PCI) and more often coronary artery bypass grafting (CABG) or optimal medical therapy alone (OMT) [1]. This disparity in treatment strategy is based on two fundamentally flawed concepts. …
Literature
1.
Fefer P, Knudtson ML, Cheema AN, et al. Current perspectives on coronary chronic total occlusions: the Canadian Multicenter Chronic Total Occlusions Registry. J Am Coll Cardiol. 2012;59:991–7.CrossRef
2.
Werner GS, Surber R, Ferrari M, Fritzenwanger M, Figulla HR. The functional reserve of collaterals supplying long-term chronic total coronary occlusions in patients without prior myocardial infarction. Eur Heart J. 2006;27:2406–12.CrossRef
3.
Stuijfzand WJ, Driessen RS, Raijmakers PG, et al. Prevalence of ischaemia in patients with a chronic total occlusion and preserved left ventricular ejection fraction. Eur Heart J Cardiovasc Imaging. 2017;18:1025–33.CrossRef
4.
Schumacher SP, Everaars H, Stuijfzand WJ, et al. Coronary collaterals and myocardial viability in patients with chronic total occlusions. EuroIntervention. 2020;16:453–61.CrossRef
5.
Sedlis SP, Hartigan PM, Teo KK, et al. Effect of PCI on long-term survival in patients with stable ischemic heart disease. N Engl J Med. 2015;373:1937–46.CrossRef
6.
Werner GS, Martin-Yuste V, Hildick-Smith D, et al. A randomized multicentre trial to compare revascularization with optimal medical therapy for the treatment of chronic total coronary occlusions. Eur Heart J. 2018;39:2484–93.CrossRef
7.
Maeremans J, Walsh S, Knaapen P, et al. The hybrid algorithm for treating chronic total occlusions in Europe: the RECHARGE registry. J Am Coll Cardiol. 2016;68:1958–70.CrossRef
8.
van Veelen A, Elias J, van Dongen IM, Hoebers LPC, Claessen BEPM, Henriques JPS. Percutaneous coronary intervention versus medical therapy for chronic total coronary occlusions: a systematic review and meta-analysis of randomised trials. Neth Heart J. 2020; https://​doi.​org/​10.​1007/​s12471-020-01503-0.CrossRef
9.
10.
11.
12.
13.
14.
15.
Maeremans J, Spratt JC, Knaapen P, et al. Towards a contemporary, comprehensive scoring system for determining technical outcomes of hybrid percutaneous chronic total occlusion treatment: the RECHARGE score. Catheter Cardiovasc Interv. 2018;91:192–202.CrossRef
16.
Morino Y, Abe M, Morimoto T, et al. Predicting successful guidewire crossing through chronic total occlusion of native coronary lesions within 30 minutes: the J‑CTO (multicenter CTO registry in Japan) score as a difficulty grading and time assessment tool. JACC Cardiovasc Interv. 2011;4:213–21.CrossRef
17.
Thompson CA. Percutaneous revascularization of coronary chronic total occlusions: the new era begins. JACC Cardiovasc Interv. 2010;3:152–4.CrossRef
Metadata
Title
Percutaneous coronary intervention for chronic total coronary occlusion: Do. Or do not. There is no try
Authors
P. Knaapen
J. P. Henriques
A. Nap
F. Arslan
Publication date
01-01-2021
Publisher
Bohn Stafleu van Loghum
Published in
Netherlands Heart Journal / Issue 1/2021
Print ISSN: 1568-5888
Electronic ISSN: 1876-6250
DOI
https://doi.org/10.1007/s12471-020-01531-w

Other articles of this Issue 1/2021

Netherlands Heart Journal 1/2021 Go to the issue

Review Article

Advances in percutaneous coronary intervention for chronic total occlusions: current antegrade dissection and reentry techniques and updated algorithm

Original Article

Development and first results of a dedicated chronic total occlusion programme

Review Article

A computed tomography algorithm for crossing coronary chronic total occlusions: riding on the wave of the proximal cap and distal vessel segment

Review Article

Complications of chronic total occlusion percutaneous coronary intervention

Review Article

Coronary physiology before and after chronic total occlusion treatment: what does it tell us?

Correction

Correction to: Percutaneous coronary intervention for chronic total coronary occlusion: Do. Or do not. There is no try

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