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Open Access 01-02-2017 | Review Article

Haemodynamic and functional consequences of the iatrogenic atrial septal defect following Mitraclip therapy

Authors: E. A. Hart, K. Zwart, A. J. Teske, M. Voskuil, P. R. Stella, S. A. J. Chamuleau, A. O. Kraaijeveld

Published in: Netherlands Heart Journal | Issue 2/2017

Abstract

Percutaneous MitraClip placement for treatment of severe mitral regurgitation in high surgical risk patients is a commonly performed procedure and requires a transseptal puncture to reach the left atrium. The resulting iatrogenic atrial septal defect (iASD) is not routinely closed, yet the haemodynamic and functional consequences of a persisting defect are not fully understood. Despite positive effects such as acute left atrial pressure relief, persisting iASDs are associated with negative consequences, namely significant bidirectional shunting and subsequent worse clinical outcome. Percutaneous closure of the iASD may therefore be desirable in selected cases. In this review we discuss the available literature on this matter.

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Title: Haemodynamic and functional consequences of the iatrogenic atrial septal defect following Mitraclip therapy
Authors: E. A. Hart
K. Zwart
A. J. Teske
M. Voskuil
P. R. Stella
S. A. J. Chamuleau
A. O. Kraaijeveld
Publication date: 01-02-2017
Publisher: Bohn Stafleu van Loghum
Published in: Netherlands Heart Journal / Issue 2/2017
Print ISSN: 1568-5888
Electronic ISSN: 1876-6250
DOI: https://doi.org/10.1007/s12471-016-0928-1

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