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Current Cardiovascular Imaging Reports
Published in: Current Cardiovascular Imaging Reports 1/2016

Open Access 01-01-2016 | Cardiac Computed Tomography (T.C. Villines, Section Editor)

Coronary Computed Tomography Angiography Derived Fractional Flow Reserve and Plaque Stress

Authors: Bjarne Linde Nørgaard, Jonathon Leipsic, Bon-Kwon Koo, Christopher K. Zarins, Jesper Møller Jensen, Niels Peter Sand, Charles A. Taylor

Published in: Current Cardiovascular Imaging Reports | Issue 1/2016

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Abstract

Fractional flow reserve (FFR) measured during invasive coronary angiography is an independent prognosticator in patients with coronary artery disease and the gold standard for decision making in coronary revascularization. The integration of computational fluid dynamics and quantitative anatomic and physiologic modeling now enables simulation of patient-specific hemodynamic parameters including blood velocity, pressure, pressure gradients, and FFR from standard acquired coronary computed tomography (CT) datasets. In this review article, we describe the potential impact on clinical practice and the science behind noninvasive coronary computed tomography (CT) angiography derived fractional flow reserve (FFRCT) as well as future applications of this technology in treatment planning and quantifying forces on atherosclerotic plaques.
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Metadata
Title
Coronary Computed Tomography Angiography Derived Fractional Flow Reserve and Plaque Stress
Authors
Bjarne Linde Nørgaard
Jonathon Leipsic
Bon-Kwon Koo
Christopher K. Zarins
Jesper Møller Jensen
Niels Peter Sand
Charles A. Taylor
Publication date
01-01-2016
Publisher
Springer US
Published in
Current Cardiovascular Imaging Reports / Issue 1/2016
Print ISSN: 1941-9066
Electronic ISSN: 1941-9074
DOI
https://doi.org/10.1007/s12410-015-9366-5

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