Published in:
01-02-2015 | Cardiac Nuclear Imaging (A Cuocolo, Section Editor)
T
1 Mapping Techniques in Assessment of Ventricular Stiffness
Authors:
Andris H. Ellims, Andrew J. Taylor
Published in:
Current Cardiovascular Imaging Reports
|
Issue 2/2015
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Abstract
Myocardial fibrosis is a fundamental process in the development of heart failure and can be quantified by cardiac magnetic resonance (CMR) imaging with T
1 mapping techniques. By measuring post-contrast myocardial T
1 time and obtaining invasively determined ventricular pressure-volume data, a mechanistic link between diffuse myocardial fibrosis and increased ventricular stiffness has recently been identified. The capacity to non-invasively evaluate diffuse myocardial fibrosis may enhance our understanding of cardiac diseases and facilitate trials of novel therapies.