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01-06-2016 | Editorial

High-risk coronary artery disease, but normal myocardial perfusion: A matter of concern?

Authors: Shu Yokota, MD, Mohamed Mouden, MD, PhD, Jan Paul Ottervanger, MD, PhD, FESC

Published in: Journal of Nuclear Cardiology | Issue 3/2016

Excerpt

Use of non-invasive cardiac imaging is recommended in numerous clinical scenarios in order to provide diagnostic and prognostic information to guide clinical decision making.1 Stress single-photon emission computed tomography (SPECT) myocardial perfusion imaging (MPI) is well validated and has proven value in identifying patients at high risk of a serious cardiac event, whereas a normal MPI study confers a benign prognosis with a low annual serious cardiac event rate of 0.6% per year.2 However, there has always been concern that MPI can miss high-risk coronary artery disease (CAD) as in patients with balanced ischemia due to flow-limiting three-vessel CAD or left main stenosis,3,4 while this group is particularly prone to adverse cardiac events and may have benefit of revascularization.4,5 …

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Title: High-risk coronary artery disease, but normal myocardial perfusion: A matter of concern?
Authors: Shu Yokota, MD
Mohamed Mouden, MD, PhD
Jan Paul Ottervanger, MD, PhD, FESC
Publication date: 01-06-2016
Publisher: Springer US
Published in: Journal of Nuclear Cardiology / Issue 3/2016
Print ISSN: 1071-3581
Electronic ISSN: 1532-6551
DOI: https://doi.org/10.1007/s12350-015-0167-7

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