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Journal of Nuclear Cardiology
Published in: Journal of Nuclear Cardiology 1/2009

01-02-2009 | Editorial

Automated assessment of serial SPECT myocardial perfusion images

Authors: Ami E. Iskandrian, MD, Ernest V. Garcia, PhD, Tracy Faber, PhD, John J. Mahmarian, MD

Published in: Journal of Nuclear Cardiology | Issue 1/2009

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Excerpt

Investigations during the first 2 decades of modern nuclear cardiology focused on methodological refinements and establishing a solid foundation for myocardial perfusion imaging (MPI) as a reliable method for detecting coronary artery disease (CAD). The 2 decades after that emphasized the prognostic value of the test in virtually every group of patients and also challenged the prevailing wisdom that coronary angiography is the undisputed “gold standard” by showing that a physiological assessment is even more meaningful than anatomic descriptors when predicting the outcome of CAD patients.1 …
Literature
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Iskandrian AE, Garcia EV, editors. Nuclear cardiac imaging: Principles and applications. 4th ed. Oxford: Oxford University Press; 2008.
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Zoghbi GJ, Dorfman TA, Iskandrian AE. The effects of medications on myocardial perfusion. J Am Coll Cardiol 2008;52:401-16.PubMedCrossRef
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Mahmarian JJ, Moye LA, Verani MS, et al. High reproducibility of myocardial perfusion defects in patients undergoing serial exercise thallium-201 tomography. Am J Cardiol 1995;75:1116-9.PubMedCrossRef
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Mahmarian JJ, Shaw LJ, Filipchuk NG, et al. A multinational study to establish the value of early adenosine technetium-99m sestamibi myocardial perfusion imaging in identifying a low-risk group for early hospital discharge after acute myocardial infarction. J Am Coll Cardiol 2006;48:2448-57.PubMedCrossRef
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Cerqueira MD, Nguyen P, Staehr PS, Underwood SR, Iskandrian AE, On behalf of the ADVANCE-MPI Trial Investigators. Effects of age, gender, obesity, and diabetes on the efficacy and safety of the selective A2A agonist Regadenoson versus adenosine in myocardial perfusion imaging: Integrated ADVANCE-MPI trial results. J Am Coll Cardiol Imaging 2008;1:307-16.
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Trimble MA, Borges-Neto S, Velazquez EJ, et al. Emerging role of myocardial perfusion imaging for cardiac resynchronization therapy. Am J Cardiol 2008;102:211-7.PubMedCrossRef
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Iskandrian AE, Garcia EV, Faber T. Analysis of serial images: A challenge and an opportunity. J Nucl Cardiol 2008;15:23-6.PubMedCrossRef
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Berman DS, Kang X, Granary H, et al. Quantitative assessment of myocardial perfusion abnormality on SPECT myocardial perfusion imaging is more reproducible than expert visual analysis. J Nucl Cardiol. doi:10.​1007/​s12350-008-9018-0.
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Shaw LJ, Berman DS, Maron DJ, et al. Optimal medical therapy with or without percutaneous coronary intervention to reduce ischemic burden: Results from the clinical outcomes utilizing revascularization and aggressive drug evaluation (COURAGE) trial nuclear substudy. Circulation 2008;117:1283-91.PubMedCrossRef
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Singh B, Bateman TM, Case JA, Heller GV. Attenuation artifact, attenuation correction, and the future of myocardial perfusion SPECT. J Nucl Cardiol 2007;14:153-64.PubMedCrossRef
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Gibbons RJ, Valeti US, Araoz PA, Jaffe AS. The quantification of infarct size. J Am Coll Cardiol 2004;44:1533-42.PubMedCrossRef
Metadata
Title
Automated assessment of serial SPECT myocardial perfusion images
Authors
Ami E. Iskandrian, MD
Ernest V. Garcia, PhD
Tracy Faber, PhD
John J. Mahmarian, MD
Publication date
01-02-2009
Publisher
Springer-Verlag
Published in
Journal of Nuclear Cardiology / Issue 1/2009
Print ISSN: 1071-3581
Electronic ISSN: 1532-6551
DOI
https://doi.org/10.1007/s12350-008-9020-6

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