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01-02-2009 | Review Article

Takotsubo cardiomyopathy: State-of-the-art review

Authors: Todd A. Dorfman, MD, Ami E. Iskandrian, MD, MACC

Published in: Journal of Nuclear Cardiology | Issue 1/2009

Abstract

Takotsubo cardiomyopathy (TC) is characterized by transient, often severe, left ventricular dysfunction and electrocardiographic changes that might mimic acute myocardial infarction in the absence of significant obstructive coronary artery disease. It is often encountered in elderly women after physical or emotional stress. Excessive catecholamine stimulation, metabolic abnormalities, and microcirculatory dysfunction are thought to be responsible for the manifestations of this disorder. This comprehensive review summarizes relevant published data, atypical presentations, pathophysiology, and management strategy. It also includes a review of 789 patients with TC including nine illustrative cases encountered at our institution.

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Title: Takotsubo cardiomyopathy: State-of-the-art review
Authors: Todd A. Dorfman, MD
Ami E. Iskandrian, MD, MACC
Publication date: 01-02-2009
Publisher: Springer-Verlag
Published in: Journal of Nuclear Cardiology / Issue 1/2009
Print ISSN: 1071-3581
Electronic ISSN: 1532-6551
DOI: https://doi.org/10.1007/s12350-008-9015-3

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