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Published in: Clinical Journal of Gastroenterology 3/2019

01-06-2019 | Case Report

Usefulness of diffusion-weighted magnetic resonance imaging for evaluating the effect of hemostatic radiotherapy for unresectable gastric cancer

Authors: Osamu Tanaka, Tatsushi Omatsu, Syuji Kariya, Ryoshu Maejima, Takuya Taniguchi, Kousei Ono, Yuka Kunishima, Masayuki Matsuo

Published in: Clinical Journal of Gastroenterology | Issue 3/2019

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Abstract

There are several reports that vouch for the usefulness of diffusion-weighted image (DWI) in making a diagnosis before treatment. However, no study has evaluated the effect of radiotherapy (RT) for unresectable gastric cancer. In the present case report, we evaluated the effectiveness of RT using DWI. An 81-year-old man was hospitalized with a broken bone and then diagnosed with advanced gastric cancer with breeding. He had chorionic renal failure and surgery was impossible. Further, contrast-enhanced computed tomography and magnetic resonance imaging (MRI) were not performed due to renal failure, whereas palliative RT was performed. We followed up the patient using blood test and MRI (DWI) to estimate whether bleeding had stopped or not after radiotherapy. Hemostasis effect was found after 2 weeks of RT. In DWI examination, there was a decrease in the tumor signal intensity 30 days after RT. Similarly, at day 60, the tumor signal intensity further decreased on DWI and the blood test results indicated no progression of anemia. At 4 months after the RT, the patient died because of respiratory failure without any bleeding. DWI is useful not only for the initial diagnosis but also for evaluating the effectiveness of RT.
Trial registration: National clinical study registered number: UMIN000026362.
Literature
2.
go back to reference Cardoso R, Coburn N, Seevaratnam R, et al. A systematic review and meta-analysis of the utility of EUS for preoperative staging for gastric cancer. Gastric Cancer. 2012;15(Suppl 1):19–26.CrossRef Cardoso R, Coburn N, Seevaratnam R, et al. A systematic review and meta-analysis of the utility of EUS for preoperative staging for gastric cancer. Gastric Cancer. 2012;15(Suppl 1):19–26.CrossRef
3.
go back to reference Saito T, Kurokawa Y, Takiguchi S, et al. Accuracy of multidetector-row CT in diagnosing lymph node metastasis in patients with gastric cancer. Eur Radiol. 2015;25:368–74.CrossRefPubMed Saito T, Kurokawa Y, Takiguchi S, et al. Accuracy of multidetector-row CT in diagnosing lymph node metastasis in patients with gastric cancer. Eur Radiol. 2015;25:368–74.CrossRefPubMed
4.
go back to reference Joo I, Lee JM, Kim JH, et al. Prospective comparison of 3T MRI with diffusion-weighted imaging and MDCT for the preoperative TNM staging of gastric cancer. J Magn Reson Imaging. 2015;41:814–21.CrossRefPubMed Joo I, Lee JM, Kim JH, et al. Prospective comparison of 3T MRI with diffusion-weighted imaging and MDCT for the preoperative TNM staging of gastric cancer. J Magn Reson Imaging. 2015;41:814–21.CrossRefPubMed
5.
go back to reference Liu S, Wang H, Guan W, et al. Preoperative apparent diffusion coefficient value of gastric cancer by diffusion-weighted imaging: correlations with postoperative TNM staging. J Magn Reson Imaging. 2015;42:837–43.CrossRefPubMed Liu S, Wang H, Guan W, et al. Preoperative apparent diffusion coefficient value of gastric cancer by diffusion-weighted imaging: correlations with postoperative TNM staging. J Magn Reson Imaging. 2015;42:837–43.CrossRefPubMed
6.
go back to reference Liu S, Zhang Y, Chen L, et al. Whole-lesion apparent diffusion coefficient histogram analysis: significance in T and N staging of gastric cancers. BMC Cancer. 2017;17:665.CrossRefPubMedPubMedCentral Liu S, Zhang Y, Chen L, et al. Whole-lesion apparent diffusion coefficient histogram analysis: significance in T and N staging of gastric cancers. BMC Cancer. 2017;17:665.CrossRefPubMedPubMedCentral
8.
go back to reference Tanaka O, Yokoi R, Mukai T, et al. Radiotherapy for gastric bleeding from tumor invasion of recurrent colon cancer with liver metastasis after resection. J Gastrointest Cancer. 2017. Tanaka O, Yokoi R, Mukai T, et al. Radiotherapy for gastric bleeding from tumor invasion of recurrent colon cancer with liver metastasis after resection. J Gastrointest Cancer. 2017.
10.
go back to reference Lee YH, Lee JW, Jang HS, et al. Palliative external beam radiotherapy for the treatment of tumor bleeding in inoperable advanced gastric cancer. BMC Cancer. 2017;17:541.CrossRefPubMedPubMedCentral Lee YH, Lee JW, Jang HS, et al. Palliative external beam radiotherapy for the treatment of tumor bleeding in inoperable advanced gastric cancer. BMC Cancer. 2017;17:541.CrossRefPubMedPubMedCentral
11.
go back to reference Suo ST, Chen XX, Fan Y, et al. Histogram analysis of apparent diffusion coefficient at 3.0 T in urinary bladder lesions: correlation with pathologic findings. Acad Radiol. 2014;21:1027–34.CrossRefPubMed Suo ST, Chen XX, Fan Y, et al. Histogram analysis of apparent diffusion coefficient at 3.0 T in urinary bladder lesions: correlation with pathologic findings. Acad Radiol. 2014;21:1027–34.CrossRefPubMed
12.
go back to reference Joye I, Deroose C, Vandecaveye V, et al. The role of diffusion-weighted MRI and 18F-FDG PET/CT in the prediction of pathologic complete response after radiochemotherapy for rectal cancer: a systematic review. Radiother Oncol. 2014;113:158–65.CrossRefPubMed Joye I, Deroose C, Vandecaveye V, et al. The role of diffusion-weighted MRI and 18F-FDG PET/CT in the prediction of pathologic complete response after radiochemotherapy for rectal cancer: a systematic review. Radiother Oncol. 2014;113:158–65.CrossRefPubMed
13.
go back to reference Kato H, Kanematsu M, Tanaka O, et al. Head and neck squamous cell carcinoma: usefulness of diffusion-weighted MR imaging in the prediction of a neoadjuvant therapeutic effect. Eur Radiol. 2009;19:103–9.CrossRefPubMed Kato H, Kanematsu M, Tanaka O, et al. Head and neck squamous cell carcinoma: usefulness of diffusion-weighted MR imaging in the prediction of a neoadjuvant therapeutic effect. Eur Radiol. 2009;19:103–9.CrossRefPubMed
14.
go back to reference Hori M, Matsuda T, Shibata A, et al. Cancer incidence and incidence rates in Japan in 2009: a study of 32 population-based cancer registries for the Monitoring of Cancer Incidence in Japan (MCIJ) project. Jpn J Clin Oncol. 2015;45:884–91.CrossRefPubMed Hori M, Matsuda T, Shibata A, et al. Cancer incidence and incidence rates in Japan in 2009: a study of 32 population-based cancer registries for the Monitoring of Cancer Incidence in Japan (MCIJ) project. Jpn J Clin Oncol. 2015;45:884–91.CrossRefPubMed
15.
go back to reference Katanoda K, Hori M, Matsuda T, Nishimoto H, et al. An updated report on the trends in cancer incidence and mortality in Japan, 1958–2013. Jpn J Clin Oncol. 2015;45:390–401.CrossRefPubMed Katanoda K, Hori M, Matsuda T, Nishimoto H, et al. An updated report on the trends in cancer incidence and mortality in Japan, 1958–2013. Jpn J Clin Oncol. 2015;45:390–401.CrossRefPubMed
Metadata
Title
Usefulness of diffusion-weighted magnetic resonance imaging for evaluating the effect of hemostatic radiotherapy for unresectable gastric cancer
Authors
Osamu Tanaka
Tatsushi Omatsu
Syuji Kariya
Ryoshu Maejima
Takuya Taniguchi
Kousei Ono
Yuka Kunishima
Masayuki Matsuo
Publication date
01-06-2019
Publisher
Springer Japan
Published in
Clinical Journal of Gastroenterology / Issue 3/2019
Print ISSN: 1865-7257
Electronic ISSN: 1865-7265
DOI
https://doi.org/10.1007/s12328-018-0923-8

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