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Clinical Journal of Gastroenterology
Published in: Clinical Journal of Gastroenterology 3/2016

01-06-2016 | Case Report

Autoimmune hepatitis following drug-induced liver injury in an elderly patient

Authors: Junichiro Kumagai, Tatsuo Kanda, Shin Yasui, Yuki Haga, Reina Sasaki, Masato Nakamura, Shuang Wu, Shingo Nakamoto, Makoto Arai, Yotaro Iino, Osamu Yokosuka

Published in: Clinical Journal of Gastroenterology | Issue 3/2016

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Abstract

We describe a case of autoimmune hepatitis (AIH) that may have occurred following drug-induced liver injury with camostat mesilate and/or benzbromarone in an elderly patient. The patient’s liver biopsy showed chronic active hepatitis and autoimmune hepatitis. Stopping the use of these drugs did not lead to complete remission, but the use of a low dose of corticosteroids completely cured his liver dysfunction. In the present case, liver dysfunction was caused by an autoimmune mechanism. Special attention should be paid to idiopathic AIH and drug-induced AIH in elderly patients.
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Metadata
Title
Autoimmune hepatitis following drug-induced liver injury in an elderly patient
Authors
Junichiro Kumagai
Tatsuo Kanda
Shin Yasui
Yuki Haga
Reina Sasaki
Masato Nakamura
Shuang Wu
Shingo Nakamoto
Makoto Arai
Yotaro Iino
Osamu Yokosuka
Publication date
01-06-2016
Publisher
Springer Japan
Published in
Clinical Journal of Gastroenterology / Issue 3/2016
Print ISSN: 1865-7257
Electronic ISSN: 1865-7265
DOI
https://doi.org/10.1007/s12328-016-0648-5

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