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Clinical Journal of Gastroenterology
Published in: Clinical Journal of Gastroenterology 6/2012

01-12-2012 | Case Report

Delayed enhanced hepatosplenic sarcoid nodules on computed tomography in an interferon-naïve hepatitis C patient: a case report and review of the literature

Authors: Takuhiro Ugajin, Hiroyuki Miyatani, Katsuhiko Matsuura, Shinya Ushimaru, Kiyoka Omoto, Mitsuhiro Nokubi, Tomohisa Ohkohchi, Yukio Yoshida

Published in: Clinical Journal of Gastroenterology | Issue 6/2012

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Abstract

A 77-year-old woman with chronic type C hepatitis was diagnosed with hypoechoic hepatosplenic nodules on ultrasonography. These lesions showed low density on precontrast computed tomography and delayed enhancement. Judging from laboratory data and images, the nodules were considered unlikely to represent malignancies and were followed conservatively. The hepatic lesions then increased in size and number. Sarcoidosis was diagnosed following liver biopsy. All nodules disappeared spontaneously within 6 years. Although some cases of interferon-induced sarcoidosis in patients with chronic hepatitis C or hepatitis C virus (HCV)-related cirrhosis have been reported recently, interferon-naïve cases are relatively rare. Delayed enhancement on computed tomography may reflect fibrosis of hepatic sarcoid lesions that have been histologically confirmed. Gastroenterologists managing patients with chronic HCV infection need to keep such cases in mind.
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Metadata
Title
Delayed enhanced hepatosplenic sarcoid nodules on computed tomography in an interferon-naïve hepatitis C patient: a case report and review of the literature
Authors
Takuhiro Ugajin
Hiroyuki Miyatani
Katsuhiko Matsuura
Shinya Ushimaru
Kiyoka Omoto
Mitsuhiro Nokubi
Tomohisa Ohkohchi
Yukio Yoshida
Publication date
01-12-2012
Publisher
Springer Japan
Published in
Clinical Journal of Gastroenterology / Issue 6/2012
Print ISSN: 1865-7257
Electronic ISSN: 1865-7265
DOI
https://doi.org/10.1007/s12328-012-0337-y

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