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Published in: Clinical Journal of Gastroenterology 1/2013

01-02-2013 | Case Report

Adult-onset diffuse nesidioblastosis causing hypoglycemia

Authors: Yasuharu Maeda, Kazunori Yokoyama, Kenichi Takeda, Jyouji Takada, Hiromi Hamada, Yasunori Hujioka, Shin-ei Kudo

Published in: Clinical Journal of Gastroenterology | Issue 1/2013

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Abstract

We report the case of a 32-year-old male with adult-onset diffuse nesidioblastosis causing hypoglycemia. Under the tentative diagnosis of insulinoma, localization procedures were carried out but no tumor was found. The presence of an insulinoma in the tail of the pancreas was suggested by selective intra-arterial calcium stimulation with hepatic venous sampling (ASVS). A distal pancreatectomy was performed under the assumed diagnosis of insulinoma in the tail based upon the ASVS. Diffuse nesidioblastosis was diagnosed by histopathological evaluation. During the post-operative course, the patient’s glucose and insulin levels were well controlled and uneventful without any medications or insulin for 7 months.
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Metadata
Title
Adult-onset diffuse nesidioblastosis causing hypoglycemia
Authors
Yasuharu Maeda
Kazunori Yokoyama
Kenichi Takeda
Jyouji Takada
Hiromi Hamada
Yasunori Hujioka
Shin-ei Kudo
Publication date
01-02-2013
Publisher
Springer Japan
Published in
Clinical Journal of Gastroenterology / Issue 1/2013
Print ISSN: 1865-7257
Electronic ISSN: 1865-7265
DOI
https://doi.org/10.1007/s12328-012-0335-0

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