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Advances in Therapy

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01-03-2019 | Liver Transplantation | Original Research

SOFA Score Can Effectively Predict the Incidence of Sepsis and 30-Day Mortality in Liver Transplant Patients: A Retrospective Study

Authors: Xiao-Wen Wang, Xing-Guo Niu, Jin-Xiu Li, Si-Sen Zhang, Xian-Fa Jiao

Published in: Advances in Therapy | Issue 3/2019

Abstract

Introduction

This study aims to evaluate the early predictive value for postoperative sepsis and 30-day mortality in liver transplant patients using sequential organ failure assessment (SOFA).

Methods

A total of 96 liver transplant patients were enrolled into this study from February 2015 to June 2018. The general information, biochemical findings, and postoperative 30-day mortality of these patients were statistically analyzed.

Results

The SOFA scores, C-reactive protein (CRP), and procalcitonin (PCT) at postoperative day (POD) 3, 5, and 7 were significantly higher in the sepsis group than in the non-sepsis group, and the differences were statistically significant. Receiver operating characteristic (ROC) curve showed that SOFA scores at POD 1, 3, 5, and 7 had higher sensitivity and specificity in predicting the incidence of sepsis within 30 days. The difference in 30-day survival rate between patients with SOFA scores of > 5 and patients with SOFA scores of ≤ 5 at POD 1–7 was statistically significant (P < 0.05).

Conclusion

SOFA scores at POD 1–7 can effectively predict the incidence of sepsis and 30-day mortality in liver transplant patients on the basis of CRP and PCT.

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Title: SOFA Score Can Effectively Predict the Incidence of Sepsis and 30-Day Mortality in Liver Transplant Patients: A Retrospective Study
Authors: Xiao-Wen Wang
Xing-Guo Niu
Jin-Xiu Li
Si-Sen Zhang
Xian-Fa Jiao
Publication date: 01-03-2019
Publisher: Springer Healthcare
Keywords: Liver Transplantation
Septicemia
Septicemia
Liver Transplantation
Liver Transplantation
Liver Transplantation
Liver Transplantation
Published in: Advances in Therapy / Issue 3/2019
Print ISSN: 0741-238X
Electronic ISSN: 1865-8652
DOI: https://doi.org/10.1007/s12325-019-0889-z

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Methods

Results

Conclusion

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