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Indian Journal of Hematology and Blood Transfusion

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01-07-2020 | Aplastic Anemia | Original Article

Response to Horse ATG (Thymogam, Bharat Serums and Vaccine, India) and Cyclosporine in Aplastic Anemia: A Single Centre, Retrospective Study of 60 Patients from Southern India

Author: Deepak S Amalnath

Published in: Indian Journal of Hematology and Blood Transfusion | Issue 3/2020

Abstract

Immunosuppressive therapy (IST), consisting of anti thymocyte globulin and cyclosporine, is the standard of care for elderly patients and in younger patients without matched donor for stem cell transplant. In this retrospective study of 60 patients, most had non severe AA (51.6%) followed by very severe AA (26.7%) and severe AA (21.7%). The response rate at 6 months was 68.3% (complete response-3.3% and partial response-65%). Of the 45 who completed 12 months follow up, RR was 54.7% (CR-7.5%, PR-47.2 %). Eight patients died during the study period. Also, Indian data on IST is briefly reviewed.

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Title: Response to Horse ATG (Thymogam, Bharat Serums and Vaccine, India) and Cyclosporine in Aplastic Anemia: A Single Centre, Retrospective Study of 60 Patients from Southern India
Author: Deepak S Amalnath
Publication date: 01-07-2020
Publisher: Springer India
Keyword: Aplastic Anemia
Published in: Indian Journal of Hematology and Blood Transfusion / Issue 3/2020
Print ISSN: 0971-4502
Electronic ISSN: 0974-0449
DOI: https://doi.org/10.1007/s12288-019-01137-2

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