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Indian Journal of Hematology and Blood Transfusion
Published in: Indian Journal of Hematology and Blood Transfusion 1/2018

01-01-2018 | Images

Stodtmeister Cells (Polymorphs with Pelger-Huët Anomaly) Showing “Faggots” in Mixed Phenotypic Acute Leukemia (T/Myeloid)

Authors: Tushar Sehgal, Pawan Singh, Esha Kaul

Published in: Indian Journal of Hematology and Blood Transfusion | Issue 1/2018

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Abstract

"Faggot" cells, named for the resemblance of multiple Auer rods to a bundle of sticks, are often considered sine qua non for acute promyelocytic leukemia. However, blasts in other acute myeloid leukemias rarely also show faggot cells. This case demonstrates faggot cells in stodtmeister cells in mixed phenotypic acute leukemia. In addition to being uncommon, this case also highlights the importance of immunophenotyping and genetic analysis in avoiding misdiagnosis and inappropriate therapy.
Literature
1.
Sehgal T, Sharma P, Varma N (2014) Faggot cells in a non-promyelocytic acute myeloid leukemia. Hematol Oncol Stem Cell Ther 7(3):120–122CrossRefPubMed
2.
Shetty VT, Mundle SD, Raza A (2001) Pseudo Pelger-Huët anomaly in myelodysplastic syndrome: hyposegmented or apoptotic neutrophil? Blood 98:1273–1275CrossRefPubMed
3.
Colella R, Hollensead SC (2012) Understanding and Recognizing the Pelger-Huët Anomaly. Am J Clin Pathol 137:358–366CrossRefPubMed
4.
Sharma P, Kumar M, Lall M, Kumar L, Bhargava M (2013) Therapy-related MDS: the importance of repeating cytogenetics and immunophenotyping in “relapsed” AML. J Hematopathol 6(4):207–211CrossRef
Metadata
Title
Stodtmeister Cells (Polymorphs with Pelger-Huët Anomaly) Showing “Faggots” in Mixed Phenotypic Acute Leukemia (T/Myeloid)
Authors
Tushar Sehgal
Pawan Singh
Esha Kaul
Publication date
01-01-2018
Publisher
Springer India
Published in
Indian Journal of Hematology and Blood Transfusion / Issue 1/2018
Print ISSN: 0971-4502
Electronic ISSN: 0974-0449
DOI
https://doi.org/10.1007/s12288-017-0811-2

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