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Indian Journal of Hematology and Blood Transfusion
Published in: Indian Journal of Hematology and Blood Transfusion 1/2017

01-03-2017 | Images

Intriguing Morphology of IgG/Lambda Secreting Myeloma Cells

Authors: Sreejesh Sreedharanunni, Narender Kumar, Neelam Varma

Published in: Indian Journal of Hematology and Blood Transfusion | Issue 1/2017

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Abstract

Myeloma cells are known to show varied morphology and various types of nuclear or cytoplasmic inclusions. There are a few reports of myeloma with presence of pseudo-Gaucher type histiocytes; however myeloma cells itself resembling storage histiocytes is distinctly uncommon. We report images of plasma cells resembling storage cells from a case of IgG/lambda plasma cell myeloma. Hematopathologist must be aware of such varied morphology of plasma cells especially while dealing with extra medullary plasmacytomas.
Literature
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Banerjee SS, Verma S, Shanks JH (2004) Morphological variants of plasma cell tumours. Histopathology 44:2–8CrossRefPubMed
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Rebeiro P, Joseph J, Dodds A, Qiu MR (2013) Plasma cell myeloma “masquerading” morphologically as a storage disorder. Pathol (Phila) 45:S96
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Jones D, Bhatia VK, Krausz T, Pinkus GS (1999) Crystal-storing histiocytosis: a disorder occurring in plasmacytic tumors expressing immunoglobulin kappa light chain. Hum Pathol 30:1441–1448CrossRefPubMed
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Shenjere P, Roy A, Eyden B, Banerjee SS (2008) Pseudo-Gaucher cells in multiple myeloma. Int J Surg Pathol 16:176–179CrossRefPubMed
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Metadata
Title
Intriguing Morphology of IgG/Lambda Secreting Myeloma Cells
Authors
Sreejesh Sreedharanunni
Narender Kumar
Neelam Varma
Publication date
01-03-2017
Publisher
Springer India
Published in
Indian Journal of Hematology and Blood Transfusion / Issue 1/2017
Print ISSN: 0971-4502
Electronic ISSN: 0974-0449
DOI
https://doi.org/10.1007/s12288-016-0724-5

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