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Breast Cancer

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01-07-2016 | Original Article

Local recurrence following treatment for breast cancer with an endoscopic nipple-sparing mastectomy

Authors: Naomi Sakamoto, Eisuke Fukuma, Ko Teraoka, Kazuei Hoshi

Published in: Breast Cancer | Issue 4/2016

Abstract

Purpose

Endoscopic nipple-sparing mastectomy (E-NSM) has been reportedly associated with smaller scars and greater patient satisfaction; however, long-term results of this procedure have not been made. The purpose of this retrospective study was to investigate the local recurrence (LR) rate and factors associated with it after E-NSM and to examine the oncologic safety of this procedure.

Methods

We reviewed the medical records of a total of 421 breasts in 404 patients who underwent E-NSM to investigate the LR rate and the factors associated with it. The clinico-pathological features and the treatment and outcomes of the patients with LRs were also examined.

Results

Eleven breasts (2.6 %) in 11 patients presented with LR as the first site of recurrence after a median follow-up time of 61 months. Among the 11 LRs, 9 patients presented with LR only, 1 patient exhibited regional lymph node recurrence, and 1 patient exhibited distant metastasis. The median time from surgery until LR was 25 months. Eight LRs developed near the original tumor site. The risk factors for LR in a multivariate analysis were a younger age of less than 40 years (p = 0.02), Stage III tumor (p = 0.01), and an inadequate surgical margin (p = 0.001). After the treatment, 6 patients had no evidence of disease, 2 patients died from metastatic disease, 2 patients experienced repeat LR, and the remaining patient who rejected excision exhibited a persistent LR.

Conclusions

E-NSM is an oncologically safe procedure and an acceptable method in selected patients requiring a mastectomy.

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Title: Local recurrence following treatment for breast cancer with an endoscopic nipple-sparing mastectomy
Authors: Naomi Sakamoto
Eisuke Fukuma
Ko Teraoka
Kazuei Hoshi
Publication date: 01-07-2016
Publisher: Springer Japan
Published in: Breast Cancer / Issue 4/2016
Print ISSN: 1340-6868
Electronic ISSN: 1880-4233
DOI: https://doi.org/10.1007/s12282-015-0600-4

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Abstract

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